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The map label for this gene is glpR [H]

Identifier: 238894458

GI number: 238894458

Start: 2350008

End: 2350757

Strand: Reverse

Name: glpR [H]

Synonym: KP1_2448

Alternate gene names: 238894458

Gene position: 2350757-2350008 (Counterclockwise)

Preceding gene: 238894461

Following gene: 238894457

Centisome position: 44.79

GC content: 62.4

Gene sequence:

>750_bases
ATGGCCATGCATAAGCTCGCCAGGCAAAAACATATTCTCGACAGGCTTAGCGAAACCGGTCAGCTGAGCATCAGCGAACT
GGTTGCAGAGTTGCAGGTGTCGGCCGATACCATTCGCCGCGATCTGAGCGACCTGGAACAACAGGGCGTGCTGCAGAAAA
GCCACGGCGGGGCCATCGCCCTTAACGTCCCGGCCATGACGCGCCAGGGCAGAAACGCTCTTCTCACCCAGACCAAGCAG
CGCCTGGGTCAGCAGGTCGCCGCGCGCATTCCCTCTGGCTCGACGCTGTTTCTCGACGCCGGAAGCACGCTGCTGGCGGT
GGCAGCCCAGCTGAAAGGGCCGTTGACCGTGATCACGGCTTCTCTGGATATCGCTCAGCTGTTCAGCGACCGTGCCGATA
TCCAGCTGATCCTGCTTGGCGGCCAGTGGGATAGTAAACAACGGCTGTTCGCCGGCAGCGCCACCCTGTCGCTGGTCACC
CGCTACCGGGCCGATATCGCCATTCTCGGTGCCTGCGCGCTCCATGCCGGGCTGGGGCTGAGCGCCAGCCAGGAAGCTGA
TGCCGACGTTAAACGCGCCATGCTGGCCGCCAGCGCCGAGCACTGGCTGGTGGCGGACCATACCAAACTCAACCGCTGCG
AACCGTGGCGGGTGGCCGGGCTCAGCGACATTCACCATCTTTTTCTTGATCGTCCCTGGGCTGAGCTGGGGGATGATCCC
GTCCTCTCTGTACATATTGCTGACGCTTAA

Upstream 100 bases:

>100_bases
CAAGTTCTTCACGATTCAACACATACAGAGCGACGTTTTGCCGTTTATTTTGCAACTTCTTGCTGTATTATGCTGTTTAT
TGCGTTAATTTGCGGAGTCA

Downstream 100 bases:

>100_bases
CAACGTGGAGAACCTGATGAGTAACAACACGATAAATATCGCCCTGATTGGCTACGGATTCGTCGGTAAGACCTTCCACG
CGCCGCTTATCCGTTCGGTG

Product: putative DeoR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MAMHKLARQKHILDRLSETGQLSISELVAELQVSADTIRRDLSDLEQQGVLQKSHGGAIALNVPAMTRQGRNALLTQTKQ
RLGQQVAARIPSGSTLFLDAGSTLLAVAAQLKGPLTVITASLDIAQLFSDRADIQLILLGGQWDSKQRLFAGSATLSLVT
RYRADIAILGACALHAGLGLSASQEADADVKRAMLAASAEHWLVADHTKLNRCEPWRVAGLSDIHHLFLDRPWAELGDDP
VLSVHIADA

Sequences:

>Translated_249_residues
MAMHKLARQKHILDRLSETGQLSISELVAELQVSADTIRRDLSDLEQQGVLQKSHGGAIALNVPAMTRQGRNALLTQTKQ
RLGQQVAARIPSGSTLFLDAGSTLLAVAAQLKGPLTVITASLDIAQLFSDRADIQLILLGGQWDSKQRLFAGSATLSLVT
RYRADIAILGACALHAGLGLSASQEADADVKRAMLAASAEHWLVADHTKLNRCEPWRVAGLSDIHHLFLDRPWAELGDDP
VLSVHIADA
>Mature_248_residues
AMHKLARQKHILDRLSETGQLSISELVAELQVSADTIRRDLSDLEQQGVLQKSHGGAIALNVPAMTRQGRNALLTQTKQR
LGQQVAARIPSGSTLFLDAGSTLLAVAAQLKGPLTVITASLDIAQLFSDRADIQLILLGGQWDSKQRLFAGSATLSLVTR
YRADIAILGACALHAGLGLSASQEADADVKRAMLAASAEHWLVADHTKLNRCEPWRVAGLSDIHHLFLDRPWAELGDDPV
LSVHIADA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=33.0508474576271, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082344, Length=233, Percent_Identity=31.3304721030043, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI226510968, Length=232, Percent_Identity=33.1896551724138, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788069, Length=222, Percent_Identity=28.3783783783784, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=26.2008733624454, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789059, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787540, Length=228, Percent_Identity=28.5087719298246, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789170, Length=236, Percent_Identity=29.6610169491525, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790635, Length=215, Percent_Identity=25.1162790697674, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26782; Mature: 26651

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMHKLARQKHILDRLSETGQLSISELVAELQVSADTIRRDLSDLEQQGVLQKSHGGAIA
CCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEE
LNVPAMTRQGRNALLTQTKQRLGQQVAARIPSGSTLFLDAGSTLLAVAAQLKGPLTVITA
EECCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEEEE
SLDIAQLFSDRADIQLILLGGQWDSKQRLFAGSATLSLVTRYRADIAILGACALHAGLGL
HHHHHHHHCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SASQEADADVKRAMLAASAEHWLVADHTKLNRCEPWRVAGLSDIHHLFLDRPWAELGDDP
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCHHHHHHHHHCCCHHHHCCCC
VLSVHIADA
EEEEEECCC
>Mature Secondary Structure 
AMHKLARQKHILDRLSETGQLSISELVAELQVSADTIRRDLSDLEQQGVLQKSHGGAIA
CHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEE
LNVPAMTRQGRNALLTQTKQRLGQQVAARIPSGSTLFLDAGSTLLAVAAQLKGPLTVITA
EECCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEEEE
SLDIAQLFSDRADIQLILLGGQWDSKQRLFAGSATLSLVTRYRADIAILGACALHAGLGL
HHHHHHHHCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SASQEADADVKRAMLAASAEHWLVADHTKLNRCEPWRVAGLSDIHHLFLDRPWAELGDDP
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCHHHHHHHHHCCCHHHHCCCC
VLSVHIADA
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]