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The map label for this gene is opdE [H]

Identifier: 238894390

GI number: 238894390

Start: 2275363

End: 2276586

Strand: Direct

Name: opdE [H]

Synonym: KP1_2373

Alternate gene names: 238894390

Gene position: 2275363-2276586 (Clockwise)

Preceding gene: 238894389

Following gene: 238894391

Centisome position: 43.35

GC content: 59.23

Gene sequence:

>1224_bases
TTGTCTTGTCGGAGAGAAATAATGTCTGCATTAGGTCACACCCGGGCACACTGGAGCGGCGTCCTGGCGATGACGCTCTG
CGTATTTGTGCTCATTGCCTCAGAATTTATGCCGGTCAGTCTGTTGACACCCATCGCGGGTGATTTACACATTACCGAGG
GATTAGCCGGTCAGGGCATTGCGCTTTCTGGCGCGCTGGCGGTACTGACCAGCCTGACGATATCCCGTCTTACCGGATCG
CTGGACCGTAAATGGCTGCTGCTGGGGCTCACGGCGTTGATGGCAGCCTCTGGGGTGATTATTGCCCTGGCGTCCAGTTT
CCCGGTTTATATGCTGGGCAGAGCGCTCATTGGGATCGTCATCGGCGGCTTCTGGTCGATGTCGGCGGCAACGGCCATTC
GGCTGGTGCCGCAACGCCAGGTCCCCCGCGCACTGGCCATCTTTAACGGCGGCAACGCGCTGGCCACCGTTGTGGCAGCG
CCGCTGGGCAGCTACCTGGGGGCCACCGTCGGCTGGCGCGGCGCCTTTTTATGTCTTGTCCCGCTGGCGGTGCTGGCCTT
CGTCTGGCAATGCATTAGCCTGCCGTCGATGAAAAGTCCGCGCGCACCACAGCGGCAGGGATCGGTGCTGCGTCTGTTCC
GTCTTTCTACGCTATCCCTGGGATTGCTGGCCTGCGGACTGTTCTTTATGGGACAGTTTACCTTATTTACCTATGTGCGA
CCGTTTCTGGAGACGGTGACCCAGGTCAGTCCTTCTGGTCTGTCCCTGATATTGCTGACAATGGGTATCGCCGGTTTTAT
CGGCACGCTGCTTATTACGACCGTTCTGAATGCCCGATTTTATCCGACGCTGGTGGCTATCCCGTTGTTAATGGCCGCAA
TTGCCGGAACGCTTCTGCTGGCCGGACACCACACGGGATCGGTCGCCGTACTGTTAAGCCTGTGGGGGCTGCTGGCGACG
GCGGCGCCCACCGGCTGGTGGACATGGATTGCGCGGACGCTGCCCGAGGATGCGGAGACGGGCGGCGGGCTGATGGTCGC
CGTGATCCAGCTATCGATAGCCCTCGGGTCAACGGTAGGCGGCCTGGTGTTTGATAGTCTGGGATGGCACAGCACTTTTG
CACTGAGCGGTCTGTTACTGCTGGGCGCGGCAGGGGTGACTTTTCTGCTCTCTGTCAAAATCAGATCATCTCAGCGCACT
GCGATTAATGAATTGAATGCATAA

Upstream 100 bases:

>100_bases
AATTCCCTTTGCGACGTTCGCGCAATTTTTTAAAACCAACCTGAAATAGATCTCCTGTGCCGGAGACATCCCCAAAGCCG
CCACGCGCCTGCGGGCGGCT

Downstream 100 bases:

>100_bases
GTCAAATCAGGAATGACAGGCTAATCGTGACCGCGTTCCTGTCTTACCATGGTGTTTTAACATGAGGGGAGCTTCACCGT
GGAATATTCAGTATTAAGTA

Product: putative MFS-family transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSCRREIMSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITEGLAGQGIALSGALAVLTSLTISRLTGS
LDRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVPRALAIFNGGNALATVVAA
PLGSYLGATVGWRGAFLCLVPLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVR
PFLETVTQVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGSVAVLLSLWGLLAT
AAPTGWWTWIARTLPEDAETGGGLMVAVIQLSIALGSTVGGLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRT
AINELNA

Sequences:

>Translated_407_residues
MSCRREIMSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITEGLAGQGIALSGALAVLTSLTISRLTGS
LDRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVPRALAIFNGGNALATVVAA
PLGSYLGATVGWRGAFLCLVPLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVR
PFLETVTQVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGSVAVLLSLWGLLAT
AAPTGWWTWIARTLPEDAETGGGLMVAVIQLSIALGSTVGGLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRT
AINELNA
>Mature_406_residues
SCRREIMSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITEGLAGQGIALSGALAVLTSLTISRLTGSL
DRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVPRALAIFNGGNALATVVAAP
LGSYLGATVGWRGAFLCLVPLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVRP
FLETVTQVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGSVAVLLSLWGLLATA
APTGWWTWIARTLPEDAETGGGLMVAVIQLSIALGSTVGGLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTA
INELNA

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=385, Percent_Identity=39.2207792207792, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1787808, Length=238, Percent_Identity=27.7310924369748, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787947, Length=295, Percent_Identity=27.1186440677966, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786595, Length=353, Percent_Identity=25.2124645892351, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42597; Mature: 42466

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCRREIMSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITEGLAGQGI
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCC
ALSGALAVLTSLTISRLTGSLDRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHH
IGGFWSMSAATAIRLVPQRQVPRALAIFNGGNALATVVAAPLGSYLGATVGWRGAFLCLV
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
PLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLETVTQVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
AGHHTGSVAVLLSLWGLLATAAPTGWWTWIARTLPEDAETGGGLMVAVIQLSIALGSTVG
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHH
GLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCC
>Mature Secondary Structure 
SCRREIMSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITEGLAGQGI
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCC
ALSGALAVLTSLTISRLTGSLDRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHH
IGGFWSMSAATAIRLVPQRQVPRALAIFNGGNALATVVAAPLGSYLGATVGWRGAFLCLV
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
PLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLETVTQVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
AGHHTGSVAVLLSLWGLLATAAPTGWWTWIARTLPEDAETGGGLMVAVIQLSIALGSTVG
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHH
GLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]