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The map label for this gene is dsdC [H]

Identifier: 238894366

GI number: 238894366

Start: 2257645

End: 2258544

Strand: Reverse

Name: dsdC [H]

Synonym: KP1_2348

Alternate gene names: 238894366

Gene position: 2258544-2257645 (Counterclockwise)

Preceding gene: 238894370

Following gene: 238894359

Centisome position: 43.03

GC content: 60.0

Gene sequence:

>900_bases
GTGCTTGAGCAACAAAGCATCCTTGCGCTGCTGCAGACCTTTGAGGTGACCGCCCGTCACCTGAGCTTTACCCTTGCCGC
GCATGAAATGAACCTAACCCAGGGAGCGGTCAGCCATCGGATCCGCAGGCTGGAGATGCACATCGGGTTTCGCCTGTTTA
TCCGCATGACGCGTAAACTGGCGCTGACAGAGGAAGGTAAGCGGCTGCTGGCGACGTTAAGCCATTCGCTGCGGGCGATT
AACGATGAAATTGAGGATATTCGCGATCAGGATCTGCGCGGCACGCTGCATATTGGTATTGCGCCGACGCTGGCCCATCT
GTGGCTAATGCCGCGTCTGCCGCGCTTTCAGACGCAATGGCCGGGACTGAATCTGCAGTTTCGCGTGCGCGCCGGGGTGA
TGGATTTTAACGAGGAGCGGGTGGATCTGGCAATTTACTACGGCGCCACGCGCTATCCCGATCTTTATCAACAGCGGCTG
ATGGCGGAAAGTTTGCTCCCGGTCTGCTCCCCGCGTTATCGCCAGCAGTATCGTCCGCTGAGCGGCGGCGACCCGGCGGC
GCTCGTCTGGATCCATGCGTGCGAATCCACCGACGTACAGGATCAATTTGCGGAATGGCGCCTGTGGTGCCAGCACAGCG
GACAGGCGTTACCTTTTGACGGCCGGTATTACGCGGTGAATAACCACTCGCTGGCCATCGAGATGGCGCTCAATGGACTC
GGCGTGGTGATGGGGCGTAAAACGCTGATCCAGCCGCTGCTCGACGCAGGCAGGCTGGTGGCCTTGTCTGAAAATGAAGC
GCCCTCGCCCTTTGGCTATGACCTGATTTGTCCGCAGGAGAACCGTTCCCGCCCGCGCTTTCGCGCCTTCAGCGAGTGGC
TGGCGGCGGAATGCGCCTAA

Upstream 100 bases:

>100_bases
TTAGTTACGATATAACTATTTAAAACCGGCAAAACTGGCCTAACAAACGAATTAAATCGGCCTATGCATGAACTCAGTTA
ATGCATAAGGGAGACAATCT

Downstream 100 bases:

>100_bases
TCGAATATTGCCAGGGTGCGCGTGCCAGAGCTTGACGTCGAAGGCCGGGCAAGGCGAAGCCGCCGCCCGGCAATGTCTCT
GAGCGGAGGTTACTTCTCCG

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLEQQSILALLQTFEVTARHLSFTLAAHEMNLTQGAVSHRIRRLEMHIGFRLFIRMTRKLALTEEGKRLLATLSHSLRAI
NDEIEDIRDQDLRGTLHIGIAPTLAHLWLMPRLPRFQTQWPGLNLQFRVRAGVMDFNEERVDLAIYYGATRYPDLYQQRL
MAESLLPVCSPRYRQQYRPLSGGDPAALVWIHACESTDVQDQFAEWRLWCQHSGQALPFDGRYYAVNNHSLAIEMALNGL
GVVMGRKTLIQPLLDAGRLVALSENEAPSPFGYDLICPQENRSRPRFRAFSEWLAAECA

Sequences:

>Translated_299_residues
MLEQQSILALLQTFEVTARHLSFTLAAHEMNLTQGAVSHRIRRLEMHIGFRLFIRMTRKLALTEEGKRLLATLSHSLRAI
NDEIEDIRDQDLRGTLHIGIAPTLAHLWLMPRLPRFQTQWPGLNLQFRVRAGVMDFNEERVDLAIYYGATRYPDLYQQRL
MAESLLPVCSPRYRQQYRPLSGGDPAALVWIHACESTDVQDQFAEWRLWCQHSGQALPFDGRYYAVNNHSLAIEMALNGL
GVVMGRKTLIQPLLDAGRLVALSENEAPSPFGYDLICPQENRSRPRFRAFSEWLAAECA
>Mature_299_residues
MLEQQSILALLQTFEVTARHLSFTLAAHEMNLTQGAVSHRIRRLEMHIGFRLFIRMTRKLALTEEGKRLLATLSHSLRAI
NDEIEDIRDQDLRGTLHIGIAPTLAHLWLMPRLPRFQTQWPGLNLQFRVRAGVMDFNEERVDLAIYYGATRYPDLYQQRL
MAESLLPVCSPRYRQQYRPLSGGDPAALVWIHACESTDVQDQFAEWRLWCQHSGQALPFDGRYYAVNNHSLAIEMALNGL
GVVMGRKTLIQPLLDAGRLVALSENEAPSPFGYDLICPQENRSRPRFRAFSEWLAAECA

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=37.6237623762376, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=31.3131313131313, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786448, Length=293, Percent_Identity=31.740614334471, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=26.9360269360269, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=25.3424657534247, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=214, Percent_Identity=28.9719626168224, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=25.6140350877193, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87081978, Length=260, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=124, Percent_Identity=31.4516129032258, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789639, Length=192, Percent_Identity=25, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788748, Length=167, Percent_Identity=27.5449101796407, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34270; Mature: 34270

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQQSILALLQTFEVTARHLSFTLAAHEMNLTQGAVSHRIRRLEMHIGFRLFIRMTRKL
CCCHHHHHHHHHHHHHHHHHHEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTEEGKRLLATLSHSLRAINDEIEDIRDQDLRGTLHIGIAPTLAHLWLMPRLPRFQTQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCC
PGLNLQFRVRAGVMDFNEERVDLAIYYGATRYPDLYQQRLMAESLLPVCSPRYRQQYRPL
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCC
SGGDPAALVWIHACESTDVQDQFAEWRLWCQHSGQALPFDGRYYAVNNHSLAIEMALNGL
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEECCCH
GVVMGRKTLIQPLLDAGRLVALSENEAPSPFGYDLICPQENRSRPRFRAFSEWLAAECA
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEQQSILALLQTFEVTARHLSFTLAAHEMNLTQGAVSHRIRRLEMHIGFRLFIRMTRKL
CCCHHHHHHHHHHHHHHHHHHEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTEEGKRLLATLSHSLRAINDEIEDIRDQDLRGTLHIGIAPTLAHLWLMPRLPRFQTQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCC
PGLNLQFRVRAGVMDFNEERVDLAIYYGATRYPDLYQQRLMAESLLPVCSPRYRQQYRPL
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCC
SGGDPAALVWIHACESTDVQDQFAEWRLWCQHSGQALPFDGRYYAVNNHSLAIEMALNGL
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEECCCH
GVVMGRKTLIQPLLDAGRLVALSENEAPSPFGYDLICPQENRSRPRFRAFSEWLAAECA
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]