| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is yciK [H]
Identifier: 238894326
GI number: 238894326
Start: 2216823
End: 2217584
Strand: Reverse
Name: yciK [H]
Synonym: KP1_2305
Alternate gene names: 238894326
Gene position: 2217584-2216823 (Counterclockwise)
Preceding gene: 238894329
Following gene: 238894325
Centisome position: 42.25
GC content: 60.24
Gene sequence:
>762_bases GTGCATTATCAACCACAACGTCACTTGCTGAAAGATCGCATCATCCTGGTCACCGGGGCCAGCGACGGGATTGGTCGTGA AGCGGCCCTGACCTACGCGCGCTATAGCGCCAGCGTTATCCTGCTGGGTCGCAACGACGACAAACTGCGCACCGTCGCCC AGGAGATTGAGCGTGAGGGTGGTATTCCCCCTCGCTGGTTTACCCTCGACCTGCTCACCTGTACGCCCCAGGCGTGCCAG CAGCTGGCGCAGCAGATCAGCATGCACTATCCCCGCCTTGACGGCGTGCTGCATAACGCTGGCCTGCTCGGCGACATCTG CCCAATGGAAGAGCAGAAGCCGGAGGTCTGGCAGCAGGTGATGCAGGTGAACGTTAATGGCACCTTTATGCTGACCCAGG CGCTTCTTCCTTTATTACTCCGTTCGGAATCGGGCTCGCTGGTCTTCACCTCATCCAGCGTCGGTCGTCAGGGCCGCGCC AACTGGGGCGCCTATGCCGTTTCCAAATTCGCCACCGAAGGGATGATGCAGGTGCTGGCCGACGAGTATCAAAGCCGCCA CCTGCGGGTAAACTGTATCAACCCCGGCGGCACTCGCACCGGAATGCGCGCCAGCGCGTTCCCGACGGAAGATCCGCTGA AACTGAAAACCCCCGCTGACATTATGCCCGTCTATCTGTGGCTGATGGGTGACGACAGTCGTCGCAAGACGGGAATGACC TTCGACGCCCAACCGGGACGTAAACCAGGAATTGCCCAATGA
Upstream 100 bases:
>100_bases CTTCGCCGATTGCAATGGCGGGCGCTTTCAGGCATAACAGCGCAAAAGTGAGATACCAAAGATGAAGCGCGATCGGGAAC CGATCGCCCAAGGAGTTGCC
Downstream 100 bases:
>100_bases GTGATGAACGCTACCGCGAACGCCAGCAGCGGCTGAAAGATAAAGTTGACGCCCGGGTGGCGGCGGCCCAGGACGAGCGC GGCATTGTGATGGTCTTTAC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 253
Protein sequence:
>253_residues MHYQPQRHLLKDRIILVTGASDGIGREAALTYARYSASVILLGRNDDKLRTVAQEIEREGGIPPRWFTLDLLTCTPQACQ QLAQQISMHYPRLDGVLHNAGLLGDICPMEEQKPEVWQQVMQVNVNGTFMLTQALLPLLLRSESGSLVFTSSSVGRQGRA NWGAYAVSKFATEGMMQVLADEYQSRHLRVNCINPGGTRTGMRASAFPTEDPLKLKTPADIMPVYLWLMGDDSRRKTGMT FDAQPGRKPGIAQ
Sequences:
>Translated_253_residues MHYQPQRHLLKDRIILVTGASDGIGREAALTYARYSASVILLGRNDDKLRTVAQEIEREGGIPPRWFTLDLLTCTPQACQ QLAQQISMHYPRLDGVLHNAGLLGDICPMEEQKPEVWQQVMQVNVNGTFMLTQALLPLLLRSESGSLVFTSSSVGRQGRA NWGAYAVSKFATEGMMQVLADEYQSRHLRVNCINPGGTRTGMRASAFPTEDPLKLKTPADIMPVYLWLMGDDSRRKTGMT FDAQPGRKPGIAQ >Mature_253_residues MHYQPQRHLLKDRIILVTGASDGIGREAALTYARYSASVILLGRNDDKLRTVAQEIEREGGIPPRWFTLDLLTCTPQACQ QLAQQISMHYPRLDGVLHNAGLLGDICPMEEQKPEVWQQVMQVNVNGTFMLTQALLPLLLRSESGSLVFTSSSVGRQGRA NWGAYAVSKFATEGMMQVLADEYQSRHLRVNCINPGGTRTGMRASAFPTEDPLKLKTPADIMPVYLWLMGDDSRRKTGMT FDAQPGRKPGIAQ
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=209, Percent_Identity=27.7511961722488, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=26.5822784810127, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=25.968992248062, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI10190704, Length=188, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=29.6747967479675, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=30.2681992337165, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI142976729, Length=214, Percent_Identity=25.7009345794392, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI5031737, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI7657478, Length=222, Percent_Identity=29.2792792792793, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=27.1276595744681, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40254992, Length=207, Percent_Identity=25.1207729468599, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI157739938, Length=201, Percent_Identity=23.3830845771144, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI126723191, Length=198, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI40548397, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI214010158, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI214010156, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI22758144, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI59889578, Length=165, Percent_Identity=29.6969696969697, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI19743808, Length=216, Percent_Identity=26.8518518518519, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787526, Length=253, Percent_Identity=83.399209486166, Blast_Score=431, Evalue=1e-122, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=27.3469387755102, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=30.8333333333333, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=28.6290322580645, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=28.1124497991968, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=31.5508021390374, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1786812, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1787905, Length=229, Percent_Identity=27.5109170305677, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=22.4066390041494, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=28.7937743190661, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560150, Length=205, Percent_Identity=29.2682926829268, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.9156626506024, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI71997402, Length=201, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17551412, Length=211, Percent_Identity=31.2796208530806, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=31.7460317460317, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17562906, Length=231, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=199, Percent_Identity=31.6582914572864, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560220, Length=241, Percent_Identity=26.1410788381743, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17570069, Length=204, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17568967, Length=246, Percent_Identity=26.0162601626016, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=29.4416243654822, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17562990, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536651, Length=188, Percent_Identity=27.1276595744681, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17544670, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193204405, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560676, Length=210, Percent_Identity=27.6190476190476, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17536025, Length=188, Percent_Identity=28.7234042553192, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17562904, Length=197, Percent_Identity=24.8730964467005, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=25.0980392156863, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=26.1044176706827, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193203115, Length=216, Percent_Identity=25.462962962963, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17508895, Length=217, Percent_Identity=24.4239631336406, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17564282, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI193203117, Length=227, Percent_Identity=25.1101321585903, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17560176, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25152911, Length=203, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562910, Length=211, Percent_Identity=24.6445497630332, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=27.2251308900524, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561402, Length=242, Percent_Identity=23.1404958677686, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI115534660, Length=240, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=30.9644670050761, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI72000259, Length=189, Percent_Identity=24.8677248677249, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538480, Length=213, Percent_Identity=24.8826291079812, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559104, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17563726, Length=203, Percent_Identity=23.6453201970443, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=234, Percent_Identity=26.0683760683761, Blast_Score=83, Evalue=4e-17, Organism=Saccharomyces cerevisiae, GI6322227, Length=208, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=227, Percent_Identity=27.3127753303965, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.0395256916996, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=28.5140562248996, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=28.968253968254, Blast_Score=98, Evalue=4e-21, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=31.5508021390374, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI21358495, Length=209, Percent_Identity=29.1866028708134, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24640492, Length=217, Percent_Identity=28.110599078341, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=28.4584980237154, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=31.219512195122, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24584748, Length=195, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI161076933, Length=195, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI45553409, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24647948, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24647946, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=29.4416243654822, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24581726, Length=218, Percent_Identity=25.6880733944954, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24647931, Length=258, Percent_Identity=27.5193798449612, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28116; Mature: 28116
Theoretical pI: Translated: 8.61; Mature: 8.61
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 5.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHYQPQRHLLKDRIILVTGASDGIGREAALTYARYSASVILLGRNDDKLRTVAQEIEREG CCCCCHHHHHHCCEEEEECCCCCCCCHHHHHHEECCEEEEEEECCCHHHHHHHHHHHHHC GIPPRWFTLDLLTCTPQACQQLAQQISMHYPRLDGVLHNAGLLGDICPMEEQKPEVWQQV CCCCCEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH MQVNVNGTFMLTQALLPLLLRSESGSLVFTSSSVGRQGRANWGAYAVSKFATEGMMQVLA HHCCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEYQSRHLRVNCINPGGTRTGMRASAFPTEDPLKLKTPADIMPVYLWLMGDDSRRKTGMT HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHEEEEEEEECCCCCCCCCCE FDAQPGRKPGIAQ ECCCCCCCCCCCC >Mature Secondary Structure MHYQPQRHLLKDRIILVTGASDGIGREAALTYARYSASVILLGRNDDKLRTVAQEIEREG CCCCCHHHHHHCCEEEEECCCCCCCCHHHHHHEECCEEEEEEECCCHHHHHHHHHHHHHC GIPPRWFTLDLLTCTPQACQQLAQQISMHYPRLDGVLHNAGLLGDICPMEEQKPEVWQQV CCCCCEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH MQVNVNGTFMLTQALLPLLLRSESGSLVFTSSSVGRQGRANWGAYAVSKFATEGMMQVLA HHCCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEYQSRHLRVNCINPGGTRTGMRASAFPTEDPLKLKTPADIMPVYLWLMGDDSRRKTGMT HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHEEEEEEEECCCCCCCCCCE FDAQPGRKPGIAQ ECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9097039; 9278503; 1885549 [H]