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The map label for this gene is btuR [H]

Identifier: 238894325

GI number: 238894325

Start: 2216236

End: 2216826

Strand: Reverse

Name: btuR [H]

Synonym: KP1_2304

Alternate gene names: 238894325

Gene position: 2216826-2216236 (Counterclockwise)

Preceding gene: 238894326

Following gene: 238894322

Centisome position: 42.24

GC content: 61.42

Gene sequence:

>591_bases
ATGAGTGATGAACGCTACCGCGAACGCCAGCAGCGGCTGAAAGATAAAGTTGACGCCCGGGTGGCGGCGGCCCAGGACGA
GCGCGGCATTGTGATGGTCTTTACCGGCAACGGCAAAGGCAAAACCACCGCCGCCTTTGGCACCGCGACCCGCGCCGTCG
GCCATGGCAAAAAAGTCGGCGTGATCCAGTTTATCAAGGGGACCTGGCCTAACGGCGAGCGTAATCTGCTGGAGCCTCAC
GGCGTCGAATTTCAGGTGATGGCCACCGGCTTCACCTGGAACACCCAGGATCGCGACAGCGACACCGCCGCCTGCCTGGC
GGTCTGGGAGCATGCCCGCCGTATGCTCGCTGACGACCAGCTCGATCTGGTGCTGCTGGACGAGCTGACCTACATGGTGG
CGTATGATTACCTGCCGCTGGAGTCGGTGCTGAGCGCCCTGCGTGAGCGCCCTGCCCATCAGTCGGTGATCATCACCGGC
CGCGGCTGTCATCGCGATATTATTGAACTGGCCGATACCGTCAGCGAACTGCGTCCGGTCAAGCATGCATTTGATGCCGG
GATTAAAGCGCAGATGGGGATAGACTACTGA

Upstream 100 bases:

>100_bases
ACATTATGCCCGTCTATCTGTGGCTGATGGGTGACGACAGTCGTCGCAAGACGGGAATGACCTTCGACGCCCAACCGGGA
CGTAAACCAGGAATTGCCCA

Downstream 100 bases:

>100_bases
GGGCCTGATAGCGCGGAAGGAAGTAAGCGTTCCGGCGGCAAGTCACCGGAACGCATAACATTAACCGTTAGTCTTATTGC
GAGTACTGGAACGACGGTTG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSDERYRERQQRLKDKVDARVAAAQDERGIVMVFTGNGKGKTTAAFGTATRAVGHGKKVGVIQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWNTQDRDSDTAACLAVWEHARRMLADDQLDLVLLDELTYMVAYDYLPLESVLSALRERPAHQSVIITG
RGCHRDIIELADTVSELRPVKHAFDAGIKAQMGIDY

Sequences:

>Translated_196_residues
MSDERYRERQQRLKDKVDARVAAAQDERGIVMVFTGNGKGKTTAAFGTATRAVGHGKKVGVIQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWNTQDRDSDTAACLAVWEHARRMLADDQLDLVLLDELTYMVAYDYLPLESVLSALRERPAHQSVIITG
RGCHRDIIELADTVSELRPVKHAFDAGIKAQMGIDY
>Mature_195_residues
SDERYRERQQRLKDKVDARVAAAQDERGIVMVFTGNGKGKTTAAFGTATRAVGHGKKVGVIQFIKGTWPNGERNLLEPHG
VEFQVMATGFTWNTQDRDSDTAACLAVWEHARRMLADDQLDLVLLDELTYMVAYDYLPLESVLSALRERPAHQSVIITGR
GCHRDIIELADTVSELRPVKHAFDAGIKAQMGIDY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=85.7142857142857, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21888; Mature: 21757

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDERYRERQQRLKDKVDARVAAAQDERGIVMVFTGNGKGKTTAAFGTATRAVGHGKKVG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCC
VIQFIKGTWPNGERNLLEPHGVEFQVMATGFTWNTQDRDSDTAACLAVWEHARRMLADDQ
CEEEEECCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
LDLVLLDELTYMVAYDYLPLESVLSALRERPAHQSVIITGRGCHRDIIELADTVSELRPV
CCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
KHAFDAGIKAQMGIDY
HHHHHCCCEEECCCCC
>Mature Secondary Structure 
SDERYRERQQRLKDKVDARVAAAQDERGIVMVFTGNGKGKTTAAFGTATRAVGHGKKVG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCC
VIQFIKGTWPNGERNLLEPHGVEFQVMATGFTWNTQDRDSDTAACLAVWEHARRMLADDQ
CEEEEECCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
LDLVLLDELTYMVAYDYLPLESVLSALRERPAHQSVIITGRGCHRDIIELADTVSELRPV
CCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
KHAFDAGIKAQMGIDY
HHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]