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The map label for this gene is ydjQ [H]

Identifier: 238894282

GI number: 238894282

Start: 2172744

End: 2173607

Strand: Reverse

Name: ydjQ [H]

Synonym: KP1_2259

Alternate gene names: 238894282

Gene position: 2173607-2172744 (Counterclockwise)

Preceding gene: 238894283

Following gene: 238894275

Centisome position: 41.41

GC content: 63.77

Gene sequence:

>864_bases
GTGGCCAGAAAGCAATCAGCCCCGCGTCTCGAGTTTGAGGCGGCGGCGATCTATGAATATCCCGAACATCTTCGCCCGTG
GCTGGAGGCGCTGCCGAAGCTGCCGGGCGTCTATCAGTTTTACGGCGACAGCGACACGATGCCGCTCTATATCGGTAAGA
GCGTCAACCTCCGCAGCCGGGTGTTATCCCACCTGCGCACCCCTGAAGAGGCCGCGATGCTGCGTCAGTCGCGGCGTATC
ACCTGGCAGCGCACCGCTGGCGAGCTGGGAGCGCTGCTGCTGGAGGCGCGGTTGATTAAAGAGCAGCAGCCGCTGTTTAA
CAAGCGGCTACGGCGTAACAAGCAGCTCTGCGCCTGGCTACTTGCGGACGACCGGCCGCAGATTGTCTATGCCCGTGAGG
TTGATTTCTCGCACCAGCAGCATCTCTATGGCCTGTTCGCCAACCGGCGAGCGGCGCTGCAGATGCTGCAGAGCCTCGCT
GACGAACAGCGCCTCTGTTATGGCCTGCTTGGTCTGGAACCACTCAGCCGCGGCCGCGCCTGCTTTCGCTCCGCGCTGGG
CCGCTGCGCCGGGGCCTGCTGTGGAAAGGAGAGCGTGGAGGCGCACAGAGAGCGCCTGCTGGCGCAGATGAGCAGACTGC
AGCTGGTGTGCTGGCCGTGGGCGGGGCCCGTGGCGCTGGAGGAGCGCGGCTCGGACATGACGCAGTATCACGTCATTCAT
AACTGGCTGTGGCTGGGCGCCGTTGAATCGCTCGACCAGGCGGCGGAGTTGACCCGTCTGCCCGCCGGATTTGACCAGGA
TGGTTACAAGATCCTCTGTAAGCCTTTGCTCAGCGGAGACTATCCGCTGCATCCGCTTGGCTGA

Upstream 100 bases:

>100_bases
TCTCTCCCCCCGCCCCGGCCTGCGCCGGGGTTATTTTTTGTCCTTTTCGCCGCAAAAATGGCCTGCTATACTGGATAGAT
AGACAGTACCAGGAGTTATT

Downstream 100 bases:

>100_bases
GAAGCCACCAATAAAAAACCGCCGGCCCTGCCCAACGCCTGATGGCATTATTGGGCAAGACCGGCGGTCTTGATTCAGTG
CGCTACATTATTCAGCAGGT

Product: nucleotide excision repair endonuclease

Products: NA

Alternate protein names: Endonuclease cho; UvrC homolog protein [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MARKQSAPRLEFEAAAIYEYPEHLRPWLEALPKLPGVYQFYGDSDTMPLYIGKSVNLRSRVLSHLRTPEEAAMLRQSRRI
TWQRTAGELGALLLEARLIKEQQPLFNKRLRRNKQLCAWLLADDRPQIVYAREVDFSHQQHLYGLFANRRAALQMLQSLA
DEQRLCYGLLGLEPLSRGRACFRSALGRCAGACCGKESVEAHRERLLAQMSRLQLVCWPWAGPVALEERGSDMTQYHVIH
NWLWLGAVESLDQAAELTRLPAGFDQDGYKILCKPLLSGDYPLHPLG

Sequences:

>Translated_287_residues
MARKQSAPRLEFEAAAIYEYPEHLRPWLEALPKLPGVYQFYGDSDTMPLYIGKSVNLRSRVLSHLRTPEEAAMLRQSRRI
TWQRTAGELGALLLEARLIKEQQPLFNKRLRRNKQLCAWLLADDRPQIVYAREVDFSHQQHLYGLFANRRAALQMLQSLA
DEQRLCYGLLGLEPLSRGRACFRSALGRCAGACCGKESVEAHRERLLAQMSRLQLVCWPWAGPVALEERGSDMTQYHVIH
NWLWLGAVESLDQAAELTRLPAGFDQDGYKILCKPLLSGDYPLHPLG
>Mature_286_residues
ARKQSAPRLEFEAAAIYEYPEHLRPWLEALPKLPGVYQFYGDSDTMPLYIGKSVNLRSRVLSHLRTPEEAAMLRQSRRIT
WQRTAGELGALLLEARLIKEQQPLFNKRLRRNKQLCAWLLADDRPQIVYAREVDFSHQQHLYGLFANRRAALQMLQSLAD
EQRLCYGLLGLEPLSRGRACFRSALGRCAGACCGKESVEAHRERLLAQMSRLQLVCWPWAGPVALEERGSDMTQYHVIHN
WLWLGAVESLDQAAELTRLPAGFDQDGYKILCKPLLSGDYPLHPLG

Specific function: Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5' site of a lesion. When a lesion remains because uvrC is not able to induce the 3' incision, cho

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrC C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788037, Length=286, Percent_Identity=74.4755244755245, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI87081999, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG [H]

EC number: NA

Molecular weight: Translated: 32780; Mature: 32649

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50164 UVRC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKQSAPRLEFEAAAIYEYPEHLRPWLEALPKLPGVYQFYGDSDTMPLYIGKSVNLRSR
CCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHH
VLSHLRTPEEAAMLRQSRRITWQRTAGELGALLLEARLIKEQQPLFNKRLRRNKQLCAWL
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
LADDRPQIVYAREVDFSHQQHLYGLFANRRAALQMLQSLADEQRLCYGLLGLEPLSRGRA
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CFRSALGRCAGACCGKESVEAHRERLLAQMSRLQLVCWPWAGPVALEERGSDMTQYHVIH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEECCCCCEEHHHCCCCHHHHHHHH
NWLWLGAVESLDQAAELTRLPAGFDQDGYKILCKPLLSGDYPLHPLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARKQSAPRLEFEAAAIYEYPEHLRPWLEALPKLPGVYQFYGDSDTMPLYIGKSVNLRSR
CCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHH
VLSHLRTPEEAAMLRQSRRITWQRTAGELGALLLEARLIKEQQPLFNKRLRRNKQLCAWL
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
LADDRPQIVYAREVDFSHQQHLYGLFANRRAALQMLQSLADEQRLCYGLLGLEPLSRGRA
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CFRSALGRCAGACCGKESVEAHRERLLAQMSRLQLVCWPWAGPVALEERGSDMTQYHVIH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEECCCCCEEHHHCCCCHHHHHHHH
NWLWLGAVESLDQAAELTRLPAGFDQDGYKILCKPLLSGDYPLHPLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]