| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is ptsA [H]
Identifier: 238894046
GI number: 238894046
Start: 1943928
End: 1946429
Strand: Direct
Name: ptsA [H]
Synonym: KP1_1993
Alternate gene names: 238894046
Gene position: 1943928-1946429 (Clockwise)
Preceding gene: 238894040
Following gene: 238894052
Centisome position: 37.04
GC content: 60.39
Gene sequence:
>2502_bases ATGGCTCTGGTCATTGAATTTACATGTGATTTGCCCAACGGCGTGCATGCGCGTCCGGCCAGTCTGGTCGAAACGCTGTG TAATCGTTTTTCATCAGCGATTGAGTGGCGGAACTTGCGCCGCGGGACCGGCGGAAATGCCAAAAGCGCGCTGGCGATTA TCGGCAGCAATACCCTGAAGGGCGACGCCTGCCAGCTGCTTATCAGCGGCGAAGATGAAGCTGAGGCATTCGCCGCGATA ACGGCCTTTATGCGCGATGAGTTTCCTCACTGTGACGCGCCGCTGCCCGCTGCGCCAACGCTGGATGTCCAGCCGGTGCC AGAGTCGCTTTCGCGGCTGAACCCGACGCTGTTTCATGCCCACCCGGTGTGCGCCGGCAGCGCGGGAGGGACGCTGGTTC ATCTCAAATCACGCGATCTGCACGAGCTGGGCGAACTGCCCGTCGCCGTCAGTCCCGAACAGGAGCAGGCGGCGCTGGAT AATGGCCTGCGCCTGCTGGTGAAAGATATCGAGCTGCGGCTGCTGGACAATGACGGCACCGCCAGCGCGATCCTGGAAGC TCACCGTTCGCTGGCGACGGATGCCTCGCTGCGCCAGCACCTGCTTGGTGGCATCCTCACCGGCCTCAGTTGCGCCCAGG CGATTGTCGCCACCGGCGACCACTTCTGCGCCCAGTTCCGCGACTCCGGCAACAGCTATCTGCAGGAGCGGGTACTGGAT GTACGCGACGTTTGCTTCCAGCTGTTACAGCATATCTACGGCGAAGCTCGTTTCCCGGCGCCGGGCCAGCTGCGGGAAGC GGCCATTTGCCTTGCCGACGAGCTGACCCCCAGCCAGTTTCTGGAACTGGATAAAACGCATCTCAAAGGACTGCTGCTGC GCAGCGGCGGCACCACCTCGCATACCGTGATTCTGGCACGCTCATTCAATATCCCTACTCTGGTGGGCGTGGATTTAGCC GCGCTGCTGCCGTGGGTAGATACGCAGGTGCAGATTGACGGCAACGCCGGGCTGTTGGTGGTGGATCCGAGTCCGGCGGT AGCGCGCTACTATCAGCAGGAGGCCTGGCTACAGGCGCAAATCCGGCAACAGCAGCAGGTATGGCTGGATAAAGCCGGGC AGACGCAAGACGGTATCCGCGTGGAAATCGCCGCCAATATCGCCCATTCGGTGGAAGCGGTGGCGGCATTCAACCAGGGC GCGCAGTCGGTAGGGTTGTTCCGCACTGAAATGCTGTATATGGATCGCCCGAGCGCGCCGTCGGAAGATGAGCTGTACAA CATCTTCTGCCAGGCGCTGGAACCCGCTGCCGGGCGCAGCATTATCGTGCGGACTATGGATATCGGCGGCGATAAGCCGG TGGCCTATCTCAACATCCCTGCGGAAAACAATCCGTTCCTCGGCTACCGCGCGGTGCGCATTTATGAAGAGTATCAGGCG CTGTTTCACACTCAGCTACGGGCGATTTTACGCGCCTCGGCACACGGCTCGCTGAAGATTATGATCCCCATGATTTCATC AATGGAAGAGATCCTGTGGGTGAAAGAGCGACTGGCGGAGGCCAAACAGTCGCTGCGCGTCGAGCAGATCCCGTTTGATG AAAAGATCCCGCTCGGCATCATGCTGGAAGTGCCGTCGGTGATGTTTATCATCGATCAGTGCTGTGAAGAGGTGGATTTC TTTAGCATCGGCAGCAACGACTTAACGCAGTATCTGCTGGCGGTGGATCGCGATAACGCGAAAGTGACGCGCCACTACAA CAGCCTGAATCCGGCCTTCCTGCGCGCGCTGGACTATGCCGTGCAGGCGGTGCATCGGCAGGGGAAATGGATTGGTCTGT GCGGCGAACTGGGGGCCAAAGGATCGGTGCTACCGCTGCTGGTAGGCCTCGGTTTAGATGAATTGAGCATGAGCGCACCG GCGATCCCGGCAACCAAATCGCGCCTGGCCCAGCTGGACAGCCGCGCCTGCCGCCAACTGCTGAATCAGGCCATGCAGTG CCGTACCTCACTGGAAGTGGAGCATCTGCTGGCCCAGTTCCGCATGCGTCAGCAGGATGTCCCGCTGGTGAGCGCCGAGT GCATTACGCTGAATAGCGACTGGCGCAGTAAGGAGGAGGTGCTGAAAGGGATGACGGATAATCTGCTATTGGCCGGCCGC TGTCGCTATCCGCGTAAGCTGGAGGCCGACCTGTGGGCTCGCGAGGCGGTGTTCTCCACTGGTCTGGGCTTTAGCTTCGC CATTCCGCACAGTAAATCCGAGCATATTGAGCAGTCGACTATCAGCGTCGCGCGGCTGGCGCAGCCGGTGATATGGGGCG ATGAAGAGGCGCAGTTTGTGATTATGCTGACGCTGAATAAGCACTCGGCGGGCGATCAGCATATGCGTATCTTCTCGCGG CTGGCGCGGCGCATTATGCACGCGGAGTTCCGTCAATCTCTGGTATCCGCGGAGAGCAGCGAGGATATTGCCGACCTGCT GCGCCGCGAGCTGGAACTGTAA
Upstream 100 bases:
>100_bases TGTGTACAATAGTCCAGTAATTGCCAGTTTTATCACCTAGTGCCCGGGGCTGTCTTTTATTACTTTTTGAGGAAATAATG GATTGCTCTGGAGGAAGGCG
Downstream 100 bases:
>100_bases TTGTCTCTCCGGCCAGCGCCGCTGGCCGGAGAGCGAGCTATAAATCCAGCACTAACCGGCCGCCTTTAGCGCGTGAGCAG CAGATCAGCATACTCTGCTG
Product: phosphoenolpyruvate-protein phosphotransferase
Products: NA
Alternate protein names: MTP 2; Phosphoenolpyruvate-protein phosphotransferase; Enzyme I-Ani; Phosphotransferase system enzyme I; Phosphocarrier protein HPr; Protein H; Fructose-like phosphotransferase enzyme IIA component; PTS system fructose-like EIIA component [H]
Number of amino acids: Translated: 833; Mature: 832
Protein sequence:
>833_residues MALVIEFTCDLPNGVHARPASLVETLCNRFSSAIEWRNLRRGTGGNAKSALAIIGSNTLKGDACQLLISGEDEAEAFAAI TAFMRDEFPHCDAPLPAAPTLDVQPVPESLSRLNPTLFHAHPVCAGSAGGTLVHLKSRDLHELGELPVAVSPEQEQAALD NGLRLLVKDIELRLLDNDGTASAILEAHRSLATDASLRQHLLGGILTGLSCAQAIVATGDHFCAQFRDSGNSYLQERVLD VRDVCFQLLQHIYGEARFPAPGQLREAAICLADELTPSQFLELDKTHLKGLLLRSGGTTSHTVILARSFNIPTLVGVDLA ALLPWVDTQVQIDGNAGLLVVDPSPAVARYYQQEAWLQAQIRQQQQVWLDKAGQTQDGIRVEIAANIAHSVEAVAAFNQG AQSVGLFRTEMLYMDRPSAPSEDELYNIFCQALEPAAGRSIIVRTMDIGGDKPVAYLNIPAENNPFLGYRAVRIYEEYQA LFHTQLRAILRASAHGSLKIMIPMISSMEEILWVKERLAEAKQSLRVEQIPFDEKIPLGIMLEVPSVMFIIDQCCEEVDF FSIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAP AIPATKSRLAQLDSRACRQLLNQAMQCRTSLEVEHLLAQFRMRQQDVPLVSAECITLNSDWRSKEEVLKGMTDNLLLAGR CRYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLAQPVIWGDEEAQFVIMLTLNKHSAGDQHMRIFSR LARRIMHAEFRQSLVSAESSEDIADLLRRELEL
Sequences:
>Translated_833_residues MALVIEFTCDLPNGVHARPASLVETLCNRFSSAIEWRNLRRGTGGNAKSALAIIGSNTLKGDACQLLISGEDEAEAFAAI TAFMRDEFPHCDAPLPAAPTLDVQPVPESLSRLNPTLFHAHPVCAGSAGGTLVHLKSRDLHELGELPVAVSPEQEQAALD NGLRLLVKDIELRLLDNDGTASAILEAHRSLATDASLRQHLLGGILTGLSCAQAIVATGDHFCAQFRDSGNSYLQERVLD VRDVCFQLLQHIYGEARFPAPGQLREAAICLADELTPSQFLELDKTHLKGLLLRSGGTTSHTVILARSFNIPTLVGVDLA ALLPWVDTQVQIDGNAGLLVVDPSPAVARYYQQEAWLQAQIRQQQQVWLDKAGQTQDGIRVEIAANIAHSVEAVAAFNQG AQSVGLFRTEMLYMDRPSAPSEDELYNIFCQALEPAAGRSIIVRTMDIGGDKPVAYLNIPAENNPFLGYRAVRIYEEYQA LFHTQLRAILRASAHGSLKIMIPMISSMEEILWVKERLAEAKQSLRVEQIPFDEKIPLGIMLEVPSVMFIIDQCCEEVDF FSIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAP AIPATKSRLAQLDSRACRQLLNQAMQCRTSLEVEHLLAQFRMRQQDVPLVSAECITLNSDWRSKEEVLKGMTDNLLLAGR CRYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLAQPVIWGDEEAQFVIMLTLNKHSAGDQHMRIFSR LARRIMHAEFRQSLVSAESSEDIADLLRRELEL >Mature_832_residues ALVIEFTCDLPNGVHARPASLVETLCNRFSSAIEWRNLRRGTGGNAKSALAIIGSNTLKGDACQLLISGEDEAEAFAAIT AFMRDEFPHCDAPLPAAPTLDVQPVPESLSRLNPTLFHAHPVCAGSAGGTLVHLKSRDLHELGELPVAVSPEQEQAALDN GLRLLVKDIELRLLDNDGTASAILEAHRSLATDASLRQHLLGGILTGLSCAQAIVATGDHFCAQFRDSGNSYLQERVLDV RDVCFQLLQHIYGEARFPAPGQLREAAICLADELTPSQFLELDKTHLKGLLLRSGGTTSHTVILARSFNIPTLVGVDLAA LLPWVDTQVQIDGNAGLLVVDPSPAVARYYQQEAWLQAQIRQQQQVWLDKAGQTQDGIRVEIAANIAHSVEAVAAFNQGA QSVGLFRTEMLYMDRPSAPSEDELYNIFCQALEPAAGRSIIVRTMDIGGDKPVAYLNIPAENNPFLGYRAVRIYEEYQAL FHTQLRAILRASAHGSLKIMIPMISSMEEILWVKERLAEAKQSLRVEQIPFDEKIPLGIMLEVPSVMFIIDQCCEEVDFF SIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAPA IPATKSRLAQLDSRACRQLLNQAMQCRTSLEVEHLLAQFRMRQQDVPLVSAECITLNSDWRSKEEVLKGMTDNLLLAGRC RYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLAQPVIWGDEEAQFVIMLTLNKHSAGDQHMRIFSRL ARRIMHAEFRQSLVSAESSEDIADLLRRELEL
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]
COG id: COG1080
COG function: function code G; Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIA type-2 domain [H]
Homologues:
Organism=Escherichia coli, GI48994992, Length=833, Percent_Identity=78.7515006002401, Blast_Score=1337, Evalue=0.0, Organism=Escherichia coli, GI1788726, Length=834, Percent_Identity=45.4436450839329, Blast_Score=689, Evalue=0.0, Organism=Escherichia coli, GI1788756, Length=459, Percent_Identity=39.8692810457516, Blast_Score=326, Evalue=4e-90, Organism=Escherichia coli, GI1789193, Length=505, Percent_Identity=32.4752475247525, Blast_Score=270, Evalue=3e-73, Organism=Escherichia coli, GI1787994, Length=227, Percent_Identity=30.8370044052863, Blast_Score=95, Evalue=2e-20, Organism=Escherichia coli, GI1786951, Length=149, Percent_Identity=26.1744966442953, Blast_Score=75, Evalue=1e-14, Organism=Escherichia coli, GI226510935, Length=312, Percent_Identity=26.6025641025641, Blast_Score=64, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008279 - InterPro: IPR006318 - InterPro: IPR018274 - InterPro: IPR023151 - InterPro: IPR000121 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR001020 - InterPro: IPR005698 - InterPro: IPR000032 - InterPro: IPR008731 - InterPro: IPR015813 [H]
Pfam domain/function: PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF00381 PTS-HPr; PF00359 PTS_EIIA_2 [H]
EC number: =2.7.3.9 [H]
Molecular weight: Translated: 91816; Mature: 91685
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: PS00369 PTS_HPR_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALVIEFTCDLPNGVHARPASLVETLCNRFSSAIEWRNLRRGTGGNAKSALAIIGSNTLK CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC GDACQLLISGEDEAEAFAAITAFMRDEFPHCDAPLPAAPTLDVQPVPESLSRLNPTLFHA CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEC HPVCAGSAGGTLVHLKSRDLHELGELPVAVSPEQEQAALDNGLRLLVKDIELRLLDNDGT CCCCCCCCCCEEEEECCCCHHHHHCCCEEECCCHHHHHHHHHHHEEEEEEEEEEECCCCH ASAILEAHRSLATDASLRQHLLGGILTGLSCAQAIVATGDHFCAQFRDSGNSYLQERVLD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHH VRDVCFQLLQHIYGEARFPAPGQLREAAICLADELTPSQFLELDKTHLKGLLLRSGGTTS HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECCCCCC HTVILARSFNIPTLVGVDLAALLPWVDTQVQIDGNAGLLVVDPSPAVARYYQQEAWLQAQ EEEEEEECCCCCEEHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHH IRQQQQVWLDKAGQTQDGIRVEIAANIAHSVEAVAAFNQGAQSVGLFRTEMLYMDRPSAP HHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCC SEDELYNIFCQALEPAAGRSIIVRTMDIGGDKPVAYLNIPAENNPFLGYRAVRIYEEYQA CHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH LFHTQLRAILRASAHGSLKIMIPMISSMEEILWVKERLAEAKQSLRVEQIPFDEKIPLGI HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCEEE MLEVPSVMFIIDQCCEEVDFFSIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYA EECCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCEEEHHCCCCCHHHHHHHHHH VQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAPAIPATKSRLAQLDSRACRQL HHHHHHCCCEEEEECCCCCCCCHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH LNQAMQCRTSLEVEHLLAQFRMRQQDVPLVSAECITLNSDWRSKEEVLKGMTDNLLLAGR HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHCCCCCCEEEECC CRYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLAQPVIWGDEEAQFV CCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCEECCCCCCEE IMLTLNKHSAGDQHMRIFSRLARRIMHAEFRQSLVSAESSEDIADLLRRELEL EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC >Mature Secondary Structure ALVIEFTCDLPNGVHARPASLVETLCNRFSSAIEWRNLRRGTGGNAKSALAIIGSNTLK EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC GDACQLLISGEDEAEAFAAITAFMRDEFPHCDAPLPAAPTLDVQPVPESLSRLNPTLFHA CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEC HPVCAGSAGGTLVHLKSRDLHELGELPVAVSPEQEQAALDNGLRLLVKDIELRLLDNDGT CCCCCCCCCCEEEEECCCCHHHHHCCCEEECCCHHHHHHHHHHHEEEEEEEEEEECCCCH ASAILEAHRSLATDASLRQHLLGGILTGLSCAQAIVATGDHFCAQFRDSGNSYLQERVLD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHH VRDVCFQLLQHIYGEARFPAPGQLREAAICLADELTPSQFLELDKTHLKGLLLRSGGTTS HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECCCCCC HTVILARSFNIPTLVGVDLAALLPWVDTQVQIDGNAGLLVVDPSPAVARYYQQEAWLQAQ EEEEEEECCCCCEEHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHH IRQQQQVWLDKAGQTQDGIRVEIAANIAHSVEAVAAFNQGAQSVGLFRTEMLYMDRPSAP HHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCC SEDELYNIFCQALEPAAGRSIIVRTMDIGGDKPVAYLNIPAENNPFLGYRAVRIYEEYQA CHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH LFHTQLRAILRASAHGSLKIMIPMISSMEEILWVKERLAEAKQSLRVEQIPFDEKIPLGI HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCEEE MLEVPSVMFIIDQCCEEVDFFSIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYA EECCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCEEEHHCCCCCHHHHHHHHHH VQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAPAIPATKSRLAQLDSRACRQL HHHHHHCCCEEEEECCCCCCCCHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH LNQAMQCRTSLEVEHLLAQFRMRQQDVPLVSAECITLNSDWRSKEEVLKGMTDNLLLAGR HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHCCCCCCEEEECC CRYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLAQPVIWGDEEAQFV CCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCEECCCCCCEE IMLTLNKHSAGDQHMRIFSRLARRIMHAEFRQSLVSAESSEDIADLLRRELEL EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8265357; 9278503; 7773398 [H]