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The map label for this gene is ompA [H]

Identifier: 238894012

GI number: 238894012

Start: 1911461

End: 1912531

Strand: Reverse

Name: ompA [H]

Synonym: KP1_1958

Alternate gene names: 238894012

Gene position: 1912531-1911461 (Counterclockwise)

Preceding gene: 238894014

Following gene: 238894010

Centisome position: 36.44

GC content: 55.84

Gene sequence:

>1071_bases
ATGAAAAAGACAGCTATCGCGATTGCAGTGGCACTGGCTGGCTTCGCTACCGTAGCGCAGGCCGCTCCGAAAGATAACAC
CTGGTATGCAGGTGGTAAACTGGGTTGGTCCCAGTATCACGACACCGGTTTCTACGGTAACGGTTTCCAGAACAACAACG
GTCCGACCCGTAACGATCAGCTTGGTGCTGGTGCGTTCGGTGGTTACCAGGTTAACCCGTACCTCGGTTTCGAAATGGGT
TATGACTGGCTGGGCCGTATGGCATATAAAGGCAGCGTTGACAACGGTGCTTTCAAAGCTCAGGGCGTTCAGCTGACCGC
TAAACTGGGTTACCCGATCACTGACGATCTGGACATCTACACCCGTCTGGGCGGCATGGTTTGGCGCGCTGACTCCAAAG
GCAACTACGCTTCTACCGGCGTTTCCCGTAGCGAACACGACACTGGCGTTTCCCCAGTATTTGCTGGCGGCGTAGAGTGG
GCTGTTACTCGTGACATCGCTACCCGTCTGGAATACCAGTGGGTTAACAACATCGGCGACGCGGGCACTGTGGGTACCCG
TCCTGATAACGGCATGCTGAGCCTGGGCGTTTCCTACCGCTTCGGTCAGGAAGATGCTGCACCGGTTGTTGCTCCGGCTC
CGGCTCCGGCTCCGGAAGTGGCTACCAAGCACTTCACCCTGAAGTCTGACGTTCTGTTCAACTTCAACAAAGCTACCCTG
AAACCGGAAGGTCAGCAGGCTCTGGATCAGCTGTACACTCAGCTGAGCAACATGGATCCGAAAGACGGTTCCGCTGTTGT
TCTGGGCTACACCGACCGCATCGGTTCCGAAGCTTACAACCAGCAGCTGTCTGAGAAACGTGCTCAGTCCGTTGTTGACT
ACCTGGTTGCTAAAGGCATCCCGGCTGGCAAAATCTCCGCTCGCGGCATGGGTGAATCCAACCCGGTTACTGGCAACACC
TGCGACAACGTGAAAGCTCGCGCTGCCCTGATCGATTGCCTGGCTCCGGATCGTCGTGTAGAGATCGAAGTTAAAGGCTA
CAAAGAAGTTGTAACTCAGCCGGCGGCTTAA

Upstream 100 bases:

>100_bases
TCAGCATAGTTAACAACAAGTCACGCCCCCGGTGAAGGATTTAACCGTGAGGTCTTTTGTAACTTCATGGCGAATTTTGG
ATGATAATGAGGCGCAAAAA

Downstream 100 bases:

>100_bases
GTTATAACCGATAAAAAAACCCGCTTCGGCGGGTTTTTTTTATGCCCTCTCGCCCACTTCAGCGGCTGAGAGCTGTGAAG
CAGTCCCCGGCCAGGGCAAC

Product: outer membrane protein A

Products: NA

Alternate protein names: Outer membrane protein II [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQYHDTGFYGNGFQNNNGPTRNDQLGAGAFGGYQVNPYLGFEMG
YDWLGRMAYKGSVDNGAFKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADSKGNYASTGVSRSEHDTGVSPVFAGGVEW
AVTRDIATRLEYQWVNNIGDAGTVGTRPDNGMLSLGVSYRFGQEDAAPVVAPAPAPAPEVATKHFTLKSDVLFNFNKATL
KPEGQQALDQLYTQLSNMDPKDGSAVVLGYTDRIGSEAYNQQLSEKRAQSVVDYLVAKGIPAGKISARGMGESNPVTGNT
CDNVKARAALIDCLAPDRRVEIEVKGYKEVVTQPAA

Sequences:

>Translated_356_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQYHDTGFYGNGFQNNNGPTRNDQLGAGAFGGYQVNPYLGFEMG
YDWLGRMAYKGSVDNGAFKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADSKGNYASTGVSRSEHDTGVSPVFAGGVEW
AVTRDIATRLEYQWVNNIGDAGTVGTRPDNGMLSLGVSYRFGQEDAAPVVAPAPAPAPEVATKHFTLKSDVLFNFNKATL
KPEGQQALDQLYTQLSNMDPKDGSAVVLGYTDRIGSEAYNQQLSEKRAQSVVDYLVAKGIPAGKISARGMGESNPVTGNT
CDNVKARAALIDCLAPDRRVEIEVKGYKEVVTQPAA
>Mature_356_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQYHDTGFYGNGFQNNNGPTRNDQLGAGAFGGYQVNPYLGFEMG
YDWLGRMAYKGSVDNGAFKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADSKGNYASTGVSRSEHDTGVSPVFAGGVEW
AVTRDIATRLEYQWVNNIGDAGTVGTRPDNGMLSLGVSYRFGQEDAAPVVAPAPAPAPEVATKHFTLKSDVLFNFNKATL
KPEGQQALDQLYTQLSNMDPKDGSAVVLGYTDRIGSEAYNQQLSEKRAQSVVDYLVAKGIPAGKISARGMGESNPVTGNT
CDNVKARAALIDCLAPDRRVEIEVKGYKEVVTQPAA

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=356, Percent_Identity=85.9550561797753, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI48994946, Length=121, Percent_Identity=35.5371900826446, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 38045; Mature: 38045

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQYHDTGFYGNGFQNNNGPTRNDQ
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
LGAGAFGGYQVNPYLGFEMGYDWLGRMAYKGSVDNGAFKAQGVQLTAKLGYPITDDLDIY
CCCCCCCCEEECCEEEHHCCHHHHHHHHCCCCCCCCCEEECCEEEEEEECCCCCCCHHHH
TRLGGMVWRADSKGNYASTGVSRSEHDTGVSPVFAGGVEWAVTRDIATRLEYQWVNNIGD
HHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHHHHHHCCCC
AGTVGTRPDNGMLSLGVSYRFGQEDAAPVVAPAPAPAPEVATKHFTLKSDVLFNFNKATL
CCCCCCCCCCCEEEEEEEEEECCCCCCCEEECCCCCCCCHHHEEEEEECCEEEECCCCCC
KPEGQQALDQLYTQLSNMDPKDGSAVVLGYTDRIGSEAYNQQLSEKRAQSVVDYLVAKGI
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
PAGKISARGMGESNPVTGNTCDNVKARAALIDCLAPDRRVEIEVKGYKEVVTQPAA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCC
>Mature Secondary Structure
MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQYHDTGFYGNGFQNNNGPTRNDQ
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
LGAGAFGGYQVNPYLGFEMGYDWLGRMAYKGSVDNGAFKAQGVQLTAKLGYPITDDLDIY
CCCCCCCCEEECCEEEHHCCHHHHHHHHCCCCCCCCCEEECCEEEEEEECCCCCCCHHHH
TRLGGMVWRADSKGNYASTGVSRSEHDTGVSPVFAGGVEWAVTRDIATRLEYQWVNNIGD
HHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHHHHHHCCCC
AGTVGTRPDNGMLSLGVSYRFGQEDAAPVVAPAPAPAPEVATKHFTLKSDVLFNFNKATL
CCCCCCCCCCCEEEEEEEEEECCCCCCCEEECCCCCCCCHHHEEEEEECCEEEECCCCCC
KPEGQQALDQLYTQLSNMDPKDGSAVVLGYTDRIGSEAYNQQLSEKRAQSVVDYLVAKGI
CCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
PAGKISARGMGESNPVTGNTCDNVKARAALIDCLAPDRRVEIEVKGYKEVVTQPAA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9524233; 1955870 [H]