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The map label for this gene is asnC [H]

Identifier: 238893987

GI number: 238893987

Start: 1881124

End: 1882524

Strand: Reverse

Name: asnC [H]

Synonym: KP1_1931

Alternate gene names: 238893987

Gene position: 1882524-1881124 (Counterclockwise)

Preceding gene: 238893988

Following gene: 238893985

Centisome position: 35.87

GC content: 58.6

Gene sequence:

>1401_bases
ATGAGCGTTGTGCCTGTAGCCGACGTACTCCAGGGCCGCGTTGCCGTTGACAGCGAAGTCACGGTCCGCGGATGGGTGCG
TACCCGCCGAGATTCTAAAGCTGGCTTTTCTTTCCTCGCCGTCTATGACGGTTCCTGCTTTGATCCTGTACAGGCCGTTA
TTAATAATTCTCTGCCCAATTACAATCAGGAAGTGCTGCGTCTGACCACCGGCTGCTCGGTGATTGTCACCGGTAAAGTC
GTAGCTTCTCAGGGTCAAGGTCAAAGCTTTGAGATCCAGGCGACCAGCGTGGAAGTGACCGGCTGGGTGGAAGACCCGGA
CACCTACCCGATGGCGGCCAAGCGCCACAGCATCGAGTATCTGCGTGAAGTAGCGCACCTGCGTCCGCGCACCAACCTGA
TTGGCGCGGTAGCCCGCGTGCGTCACACCCTGGCGCAGGCGCTGCACCGCTTCTTCAACGAACAGGGCTTCTTCTGGGTT
TCCACCCCGCTGATCACCGCCTCCGATACCGAAGGCGCCGGCGAAATGTTCCGCGTGTCGACGCTGGATCTGGAAAACCT
GCCGCGTAACGATCAGGGCAAAGTCGATTTCGACAAAGACTTCTTCGGTAAAGAGTCGTTCCTGACCGTTTCCGGCCAGC
TGAACGGCGAGACCTACGCCTGTGCGCTGTCGAAGATTTATACCTTCGGCCCGACCTTCCGCGCCGAGAACTCCAACACC
AGCCGCCACCTGGCGGAATTCTGGATGCTGGAGCCGGAAGTGGCCTTCGCCAACCTGAACGACGTTGCCGGCCTGGCGGA
AGCGATGCTCAAGTACGTCTTCAAAGCGGTACTGGAAGAGCGTGCGGACGACATGCAGTTCTTCGCCGAGCGCGTGGATA
AAGACGCTATCGACCGTCTGCAGCGCTTTATCACCGCTGATTTTGCCCAGGTGGATTACACCGACGCCGTCACCATTCTG
GAAAACTGCGGCAAACAGTTCGAGAACCCGGTGTACTGGGGCGTGGATCTCTCCTCTGAGCACGAACGTTACCTGGCCGA
AGAGCACTTCAAAGCGCCGGTGGTGGTGAAAAACTACCCGAAAGACATTAAAGCGTTCTATATGCGCCTTAACGAAGACG
GTAAAACCGTCGCGGCAATGGACGTTCTGGCGCCGGGCATCGGCGAGATTATCGGCGGTTCCCAGCGTGAAGAGCGTCTC
GACGTGCTTGACGCGCGTATGGCAGAGATGGGGCTTAACAAAGAAGACTACTGGTGGTATCGCGACCTGCGTCGCTACGG
CACCGTGCCGCATTCCGGCTTCGGTCTGGGCTTCGAACGCCTCATCGCTTACGTCACCGGCGTGCAGAACGTCCGCGATG
TTATTCCGTTCCCGCGGACGCCGCGCAACGCGACATTCTAA

Upstream 100 bases:

>100_bases
TGCGAAATCTACTTGTCTGATGGAAGATGACAGGTAACATAGATATCCCCCCGCTGTTGGGGGAAGAGACTTTTTTATTG
GACTACATAGAGAGATTATT

Downstream 100 bases:

>100_bases
ATTTTTCTGACATCAATCTGAAAGGCCAGCGCAAGCTGGCCTTTTTTTATGTCAATTACTGTTAGTAAAATTCAACAACC
TTAAACATCAAGACCTGGAA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGFSFLAVYDGSCFDPVQAVINNSLPNYNQEVLRLTTGCSVIVTGKV
VASQGQGQSFEIQATSVEVTGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMLEPEVAFANLNDVAGLAEAMLKYVFKAVLEERADDMQFFAERVDKDAIDRLQRFITADFAQVDYTDAVTIL
ENCGKQFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF

Sequences:

>Translated_466_residues
MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGFSFLAVYDGSCFDPVQAVINNSLPNYNQEVLRLTTGCSVIVTGKV
VASQGQGQSFEIQATSVEVTGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMLEPEVAFANLNDVAGLAEAMLKYVFKAVLEERADDMQFFAERVDKDAIDRLQRFITADFAQVDYTDAVTIL
ENCGKQFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
>Mature_465_residues
SVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGFSFLAVYDGSCFDPVQAVINNSLPNYNQEVLRLTTGCSVIVTGKVV
ASQGQGQSFEIQATSVEVTGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVS
TPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTS
RHLAEFWMLEPEVAFANLNDVAGLAEAMLKYVFKAVLEERADDMQFFAERVDKDAIDRLQRFITADFAQVDYTDAVTILE
NCGKQFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=41.2526997840173, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI4758762, Length=452, Percent_Identity=27.212389380531, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI45439306, Length=352, Percent_Identity=28.6931818181818, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=95.9227467811159, Blast_Score=934, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=474, Percent_Identity=22.3628691983122, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788173, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=467, Percent_Identity=28.2655246252677, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=30.4651162790698, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=345, Percent_Identity=26.9565217391304, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=466, Percent_Identity=35.6223175965665, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=456, Percent_Identity=30.0438596491228, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=485, Percent_Identity=23.9175257731959, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI19922416, Length=463, Percent_Identity=35.85313174946, Blast_Score=278, Evalue=8e-75,
Organism=Drosophila melanogaster, GI19921528, Length=465, Percent_Identity=27.741935483871, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI17136276, Length=493, Percent_Identity=26.7748478701826, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52496; Mature: 52365

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGFSFLAVYDGSCFDPVQAVINNSLPN
CCCCCHHHHHCCCEECCCCEEEHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
YNQEVLRLTTGCSVIVTGKVVASQGQGQSFEIQATSVEVTGWVEDPDTYPMAAKRHSIEY
CCHHHHHHHCCCEEEEEEEEEECCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
EECHHHCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMLEPEVAFANLNDVAGLAEAMLKYVFKAVLEERADDMQFFAERVDKDAIDRL
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QRFITADFAQVDYTDAVTILENCGKQFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGFSFLAVYDGSCFDPVQAVINNSLPN
CCCCHHHHHCCCEECCCCEEEHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
YNQEVLRLTTGCSVIVTGKVVASQGQGQSFEIQATSVEVTGWVEDPDTYPMAAKRHSIEY
CCHHHHHHHCCCEEEEEEEEEECCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
EECHHHCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMLEPEVAFANLNDVAGLAEAMLKYVFKAVLEERADDMQFFAERVDKDAIDRL
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QRFITADFAQVDYTDAVTILENCGKQFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA