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The map label for this gene is artM [H]

Identifier: 238893922

GI number: 238893922

Start: 1798812

End: 1799480

Strand: Reverse

Name: artM [H]

Synonym: KP1_1859

Alternate gene names: 238893922

Gene position: 1799480-1798812 (Counterclockwise)

Preceding gene: 238893923

Following gene: 238893921

Centisome position: 34.29

GC content: 57.7

Gene sequence:

>669_bases
ATGCTCGACTATTTACCCGAACTGCTGAAAGGACTGCATACCAGCCTGACGCTGACCGTGGCGTCGATTATCGTGGCGCT
GATCCTGTCGCTGATCCTCACCATTATCCTGACCCTGAAGACGCCGGGGCTGGTATGGATAGTGCGCGGCTATATCACCT
TGTTTACCGGTACGCCGCTGCTGGTGCAGATATTCCTGATCTACTACGGCCCGGGACAGTTCCCTTCGCTGCAGGAGTAT
CCGTGGCTGTGGCATCTTATCTCCGAGCCGTGGCTGTGCGCCCTGATCGCTCTGTCGCTCAACAGCGCCGCCTACACCAC
TCAGCTGTTTTATGGCGCCATCCGGGCGATCCCCGACGGGCAATGGCAGTCCTGTAGCGCGCTGGGAATGAGTAAAAAGG
ATACCCTAGCGATCCTGCTGCCGTACGCCTTTAAGCGTGCGCTATCGTCCTATTCCAACGAAGTGGTGCTGGTTTTCAAG
AGTACCTCTCTGGCCTACACCATCACGCTGATGGAAGTGATGGGCCACGGCCAGCTGCTGTATGGACGCACCTACGACGT
GATGGTGTTCGGCGCCGCCGGGATTATCTATCTCATCGTTAATGGACTGCTGACGCTGCTGATGCGCCTGGTGGAACGCA
AAGCGCTGGCCTTCGAGCGACGTAGCTAG

Upstream 100 bases:

>100_bases
TCATTGCGGCGGCAATCTATCTCGTCATCACCCTGTTGAGTCAATACATCCTTAAGCGGATTGACCAGCGTGCGACGCGC
TTCGAACGGAGACCAGGCTG

Downstream 100 bases:

>100_bases
CACCTGAGCATATTGCATAAAAAGCAAACAGCAAGGCGGACAAGTCAAACACCTGTCCGTCTTTTTTTATGACGATAGAA
ATACTTAATCATTTTTATTG

Product: arginine transporter permease subunit ArtM

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MLDYLPELLKGLHTSLTLTVASIIVALILSLILTIILTLKTPGLVWIVRGYITLFTGTPLLVQIFLIYYGPGQFPSLQEY
PWLWHLISEPWLCALIALSLNSAAYTTQLFYGAIRAIPDGQWQSCSALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
STSLAYTITLMEVMGHGQLLYGRTYDVMVFGAAGIIYLIVNGLLTLLMRLVERKALAFERRS

Sequences:

>Translated_222_residues
MLDYLPELLKGLHTSLTLTVASIIVALILSLILTIILTLKTPGLVWIVRGYITLFTGTPLLVQIFLIYYGPGQFPSLQEY
PWLWHLISEPWLCALIALSLNSAAYTTQLFYGAIRAIPDGQWQSCSALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
STSLAYTITLMEVMGHGQLLYGRTYDVMVFGAAGIIYLIVNGLLTLLMRLVERKALAFERRS
>Mature_222_residues
MLDYLPELLKGLHTSLTLTVASIIVALILSLILTIILTLKTPGLVWIVRGYITLFTGTPLLVQIFLIYYGPGQFPSLQEY
PWLWHLISEPWLCALIALSLNSAAYTTQLFYGAIRAIPDGQWQSCSALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
STSLAYTITLMEVMGHGQLLYGRTYDVMVFGAAGIIYLIVNGLLTLLMRLVERKALAFERRS

Specific function: Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787086, Length=222, Percent_Identity=91.4414414414414, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788226, Length=223, Percent_Identity=35.4260089686099, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1788645, Length=214, Percent_Identity=32.7102803738318, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787087, Length=237, Percent_Identity=27.4261603375527, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787030, Length=217, Percent_Identity=27.1889400921659, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=29.3838862559242, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786874, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786873, Length=216, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24758; Mature: 24758

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYLPELLKGLHTSLTLTVASIIVALILSLILTIILTLKTPGLVWIVRGYITLFTGTPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPSLQEYPWLWHLISEPWLCALIALSLNSAAYTTQLFYGAIRAIPDG
HHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
QWQSCSALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMEVMGHGQLL
CCCCHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEE
YGRTYDVMVFGAAGIIYLIVNGLLTLLMRLVERKALAFERRS
ECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDYLPELLKGLHTSLTLTVASIIVALILSLILTIILTLKTPGLVWIVRGYITLFTGTPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPSLQEYPWLWHLISEPWLCALIALSLNSAAYTTQLFYGAIRAIPDG
HHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
QWQSCSALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMEVMGHGQLL
CCCCHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEE
YGRTYDVMVFGAAGIIYLIVNGLLTLLMRLVERKALAFERRS
ECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]