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The map label for this gene is yicI [C]

Identifier: 238893878

GI number: 238893878

Start: 1749182

End: 1751545

Strand: Reverse

Name: yicI [C]

Synonym: KP1_1811

Alternate gene names: 238893878

Gene position: 1751545-1749182 (Counterclockwise)

Preceding gene: 238893879

Following gene: 238893876

Centisome position: 33.37

GC content: 59.98

Gene sequence:

>2364_bases
ATGAAGACGCTGAAACACTGGAGTTTGCATCAACAGCTGGAGCATCACGTTGAACTGACGGTCGATGGCCAGCACACCCT
GTGCCTGTACGTACTGGAAGAGAATTTGTTCCGCGTCCTGCTAAAACGCCAGGGCCAGCTGGCGCTGGATCGCACCTGGA
GCATCGCTCCACAGCAGGATGTGCCGTGGGAAGGCCGCGCCCGGGATGACCTCAGCGGTTTTAGTCTCCCGGCCTGGCAG
CTGACCCGGGAGGGCGATACGCTGACTATCGCCACCCGCCAGCTGCGCGTCACCGTTCACCAGCCGCTGTGGCTGGAGTG
GAGCTATCGCGACGAGGCCGGCGAATGGCAGCCGCTTGCCAATGACCGTCCGACCAGCGCCTACCTGGCGAATGCCCACG
GCGACGGCGTCGCCCATTATCTGAGCCGCCGCAAAGACGAGCGTTTCTACGGCCTGGGCGAAAAGGCCGGCGACCTGCAG
CGCACCGGTAAACGCTATGAGATGCGTAACCTCGATGCCATGGGCTACAACGCCGTCAGCACTGACCCGCTGTATAAACA
TATTCCGTTCACCATCACCCAGCGCAGCGATATCAGCTACGGCCTGTTCTATGACAACCTGAGCAGCTGCTGGCTGGATC
TGGGGAACGAGATCGACAACTACCACACCGCCTATCGCCGCTGGCAGGCGGAAGCCGGCGACATCGATTATTACCTGTTT
ACCGGTAAGCAGGTGCTGGATGTGACCAAAGCCTTCGTTCGCCTGACCGGTAAAACGCTGTTTGGACCCAAATGGAGCCT
CGGCTACAGCGGCTCCACCATGCACTATACCGACGCGCCGGATGCGCAAAATCAGCTGATGAACTTTATCCGCCTGTGCG
AGCAGCACGCGATCCCCTGCGATTCGTTCCAGCTCTCTTCCGGCTATACCTCAATCAACGGCAAGCGCTACGTCTTTAAC
TGGAACTACGACAAGGTGCCGCAGCCCAAAGTGATGAGCCAGTCGTTTCACGATGCCGGGCTGAAGCTGGCCGCCAATAT
CAAACCGTGCCTGCTGCAGGATCACCCGCGCTACGGCGAGGTGGCGGAGCGCGGTCTCTTCATTCGCGATTCGCAAACTG
ACGCTCCGGAGCGTTCCAGCTTCTGGGATGATGAAGGGTCGCATCTCGATTTCACCAATCCGCAAACCGTGGCCTGGTGG
CAGGAAGGCGTGACCACCCAGCTACTGGAGATGGGCATCGATTCGACCTGGAACGATAATAACGAATACGAAGTATGGGA
CGGCGAAGCCCGCTGCTACGGCTTTGGCCGCGAAATCGCCATCAAACATATTCGCCCGGTGATGCCGCTGTTGATGATGC
GCGCCTCGCTGGAAGCCCAGCAGCGCTTTGCGCCGCAAAAGCGCCCATATCTGATCTCCCGCTCCGGCTGCGCCGGGATG
CAGCGCTACGTCCAGACCTGGAGCGGCGACAACCGCACCAACTGGGATACGCTGCGCTATAACATCCGCATGGGCCTGGG
GATGAGCCTTTCCGGGCTGTTTAACGTCGGCCACGACGTCGGCGGTTTCTCCGGCGATAAACCCGAGCCGGAACTGTTTG
TGCGCTGGGTACAAAATGGCGTCATGCATCCGCGCTTTACCATTCACTCGTGGAATGACGACCAGACGGTAAACGAAGCA
TGGATGTATCCGGCCATCACTCCGGCGATCCGCTCAGCCATTGAGCTGCGCTACCGCCTGCTGCCCTATCTGTACACTCT
GCTATGGCAGGCGCATGCTGATGATGAGCCGATGCTCCGCCCGACCTTCCTCGATCACCAGCACGATGCGCAGACCTTCG
CCGAATGCGATGACTTCCTGCTGGGCCGCGACCTGCTGGTGGCCAGCGTGGTCGAGCCTGGCGCCCGCCAGCGTGAAGTA
TGGCTGCCAGATAATCAGGCCGGTTGGTACGATTTCTACAGCCATCAGTGGTTCGCCGGCGGCCAGTGGGTGACGCTGGA
CGCGCCGCTGGAAAAACTGCCGCTGTTGGTCCGCGCCGGCGCCGGTCTGCCGCTTAGTGAACGTATCAGCCATGTCGATG
CGCAAAAAGACGATCGTCGCGAACTGCAGCTGTTCCCGCTGAAAGGTACCGGCTCAACCCGCGGTCTGCTGTTTGAAGAC
GACGGCGAAAGCTGGGGCTATAAACAGGGGGATGCGCTATGGCTGGAGTGGGAAATGACCTGCAGCGCCAGCAGCATAAA
CCTGGATATCAACGCCCGCGGCAACTATCGCCCGGCTTGGAAAGCGCTGAAGCTGTCATTACCGGTAGGAGAAAAGCGTA
AGCTGCTGGTGAATGGCGTTGAAGGGACCGAGTGGAGACTCTGA

Upstream 100 bases:

>100_bases
ATTTATCGCCATGGGTTTCTTTGACCTGATTGGCGCCGTTTTCCTGGTGGCATTTATTGCTGAACGTCGCGCCAAGCGCG
CCTGAGAGTGGATGTAAGAT

Downstream 100 bases:

>100_bases
CCATAGGCCGGCTGAAATGCCGGTATTGGTGGTCTAGAAATCCCCGGTGGCGCTATCGCTTACCGGGGCTACAGCACTAT
GCGGTTTGGTAGCCCGGGTA

Product: putative alpha-xylosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MKTLKHWSLHQQLEHHVELTVDGQHTLCLYVLEENLFRVLLKRQGQLALDRTWSIAPQQDVPWEGRARDDLSGFSLPAWQ
LTREGDTLTIATRQLRVTVHQPLWLEWSYRDEAGEWQPLANDRPTSAYLANAHGDGVAHYLSRRKDERFYGLGEKAGDLQ
RTGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITQRSDISYGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDIDYYLF
TGKQVLDVTKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEQHAIPCDSFQLSSGYTSINGKRYVFN
WNYDKVPQPKVMSQSFHDAGLKLAANIKPCLLQDHPRYGEVAERGLFIRDSQTDAPERSSFWDDEGSHLDFTNPQTVAWW
QEGVTTQLLEMGIDSTWNDNNEYEVWDGEARCYGFGREIAIKHIRPVMPLLMMRASLEAQQRFAPQKRPYLISRSGCAGM
QRYVQTWSGDNRTNWDTLRYNIRMGLGMSLSGLFNVGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDQTVNEA
WMYPAITPAIRSAIELRYRLLPYLYTLLWQAHADDEPMLRPTFLDHQHDAQTFAECDDFLLGRDLLVASVVEPGARQREV
WLPDNQAGWYDFYSHQWFAGGQWVTLDAPLEKLPLLVRAGAGLPLSERISHVDAQKDDRRELQLFPLKGTGSTRGLLFED
DGESWGYKQGDALWLEWEMTCSASSINLDINARGNYRPAWKALKLSLPVGEKRKLLVNGVEGTEWRL

Sequences:

>Translated_787_residues
MKTLKHWSLHQQLEHHVELTVDGQHTLCLYVLEENLFRVLLKRQGQLALDRTWSIAPQQDVPWEGRARDDLSGFSLPAWQ
LTREGDTLTIATRQLRVTVHQPLWLEWSYRDEAGEWQPLANDRPTSAYLANAHGDGVAHYLSRRKDERFYGLGEKAGDLQ
RTGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITQRSDISYGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDIDYYLF
TGKQVLDVTKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEQHAIPCDSFQLSSGYTSINGKRYVFN
WNYDKVPQPKVMSQSFHDAGLKLAANIKPCLLQDHPRYGEVAERGLFIRDSQTDAPERSSFWDDEGSHLDFTNPQTVAWW
QEGVTTQLLEMGIDSTWNDNNEYEVWDGEARCYGFGREIAIKHIRPVMPLLMMRASLEAQQRFAPQKRPYLISRSGCAGM
QRYVQTWSGDNRTNWDTLRYNIRMGLGMSLSGLFNVGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDQTVNEA
WMYPAITPAIRSAIELRYRLLPYLYTLLWQAHADDEPMLRPTFLDHQHDAQTFAECDDFLLGRDLLVASVVEPGARQREV
WLPDNQAGWYDFYSHQWFAGGQWVTLDAPLEKLPLLVRAGAGLPLSERISHVDAQKDDRRELQLFPLKGTGSTRGLLFED
DGESWGYKQGDALWLEWEMTCSASSINLDINARGNYRPAWKALKLSLPVGEKRKLLVNGVEGTEWRL
>Mature_787_residues
MKTLKHWSLHQQLEHHVELTVDGQHTLCLYVLEENLFRVLLKRQGQLALDRTWSIAPQQDVPWEGRARDDLSGFSLPAWQ
LTREGDTLTIATRQLRVTVHQPLWLEWSYRDEAGEWQPLANDRPTSAYLANAHGDGVAHYLSRRKDERFYGLGEKAGDLQ
RTGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITQRSDISYGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDIDYYLF
TGKQVLDVTKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEQHAIPCDSFQLSSGYTSINGKRYVFN
WNYDKVPQPKVMSQSFHDAGLKLAANIKPCLLQDHPRYGEVAERGLFIRDSQTDAPERSSFWDDEGSHLDFTNPQTVAWW
QEGVTTQLLEMGIDSTWNDNNEYEVWDGEARCYGFGREIAIKHIRPVMPLLMMRASLEAQQRFAPQKRPYLISRSGCAGM
QRYVQTWSGDNRTNWDTLRYNIRMGLGMSLSGLFNVGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDQTVNEA
WMYPAITPAIRSAIELRYRLLPYLYTLLWQAHADDEPMLRPTFLDHQHDAQTFAECDDFLLGRDLLVASVVEPGARQREV
WLPDNQAGWYDFYSHQWFAGGQWVTLDAPLEKLPLLVRAGAGLPLSERISHVDAQKDDRRELQLFPLKGTGSTRGLLFED
DGESWGYKQGDALWLEWEMTCSASSINLDINARGNYRPAWKALKLSLPVGEKRKLLVNGVEGTEWRL

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=675, Percent_Identity=30.2222222222222, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI38202257, Length=675, Percent_Identity=30.2222222222222, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI66346737, Length=661, Percent_Identity=29.1981845688351, Blast_Score=270, Evalue=4e-72,
Organism=Homo sapiens, GI119393895, Length=550, Percent_Identity=27.8181818181818, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI119393893, Length=550, Percent_Identity=27.8181818181818, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI119393891, Length=550, Percent_Identity=27.8181818181818, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI221316699, Length=653, Percent_Identity=24.1960183767228, Blast_Score=156, Evalue=9e-38,
Organism=Homo sapiens, GI157364974, Length=673, Percent_Identity=25.55720653789, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI310115361, Length=270, Percent_Identity=34.0740740740741, Blast_Score=124, Evalue=4e-28,
Organism=Escherichia coli, GI2367256, Length=579, Percent_Identity=24.3523316062176, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI2367323, Length=378, Percent_Identity=26.984126984127, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71991189, Length=631, Percent_Identity=28.6846275752773, Blast_Score=245, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17560800, Length=617, Percent_Identity=27.5526742301459, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17560798, Length=617, Percent_Identity=27.5526742301459, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI32563849, Length=316, Percent_Identity=29.4303797468354, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71985706, Length=673, Percent_Identity=23.3283803863299, Blast_Score=106, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319706, Length=618, Percent_Identity=27.9935275080906, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24643749, Length=606, Percent_Identity=26.4026402640264, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643753, Length=606, Percent_Identity=26.4026402640264, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643751, Length=606, Percent_Identity=26.4026402640264, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643746, Length=606, Percent_Identity=26.4026402640264, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI21357605, Length=606, Percent_Identity=26.4026402640264, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24650054, Length=377, Percent_Identity=25.7294429708223, Blast_Score=84, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 90560; Mature: 90560

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00066 HMG_COA_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLKHWSLHQQLEHHVELTVDGQHTLCLYVLEENLFRVLLKRQGQLALDRTWSIAPQQD
CCCCHHHHHHHHHHCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCCEEECCEECCCCCCC
VPWEGRARDDLSGFSLPAWQLTREGDTLTIATRQLRVTVHQPLWLEWSYRDEAGEWQPLA
CCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEEECCEEEEEECCCCCCCCCCCC
NDRPTSAYLANAHGDGVAHYLSRRKDERFYGLGEKAGDLQRTGKRYEMRNLDAMGYNAVS
CCCCCCEEEECCCCCHHHHHHHHCCCCCEECCCCCCCHHHHCCCHHHHCCCCCCCCCCCC
TDPLYKHIPFTITQRSDISYGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDIDYYLF
CCCCHHCCCEEEEECCCCEEEEEHHCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEE
TGKQVLDVTKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEQHAIPC
CCCHHHHHHHHHHHHCCCEECCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCC
DSFQLSSGYTSINGKRYVFNWNYDKVPQPKVMSQSFHDAGLKLAANIKPCLLQDHPRYGE
CCEEECCCCEECCCCEEEEECCCCCCCCCHHHHCCHHHCCEEEECCCCCEEECCCCCHHH
VAERGLFIRDSQTDAPERSSFWDDEGSHLDFTNPQTVAWWQEGVTTQLLEMGIDSTWNDN
HHHCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCEEEHHHCCHHHHHHHHCCCCCCCCC
NEYEVWDGEARCYGFGREIAIKHIRPVMPLLMMRASLEAQQRFAPQKRPYLISRSGCAGM
CCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHH
QRYVQTWSGDNRTNWDTLRYNIRMGLGMSLSGLFNVGHDVGGFSGDKPEPELFVRWVQNG
HHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
VMHPRFTIHSWNDDQTVNEAWMYPAITPAIRSAIELRYRLLPYLYTLLWQAHADDEPMLR
CCCCEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTFLDHQHDAQTFAECDDFLLGRDLLVASVVEPGARQREVWLPDNQAGWYDFYSHQWFAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEECCCCCEECC
GQWVTLDAPLEKLPLLVRAGAGLPLSERISHVDAQKDDRRELQLFPLKGTGSTRGLLFED
CEEEEECCCHHHCCEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEC
DGESWGYKQGDALWLEWEMTCSASSINLDINARGNYRPAWKALKLSLPVGEKRKLLVNGV
CCCCCCCCCCCEEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEECC
EGTEWRL
CCCCCCC
>Mature Secondary Structure
MKTLKHWSLHQQLEHHVELTVDGQHTLCLYVLEENLFRVLLKRQGQLALDRTWSIAPQQD
CCCCHHHHHHHHHHCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCCEEECCEECCCCCCC
VPWEGRARDDLSGFSLPAWQLTREGDTLTIATRQLRVTVHQPLWLEWSYRDEAGEWQPLA
CCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEEECCEEEEEECCCCCCCCCCCC
NDRPTSAYLANAHGDGVAHYLSRRKDERFYGLGEKAGDLQRTGKRYEMRNLDAMGYNAVS
CCCCCCEEEECCCCCHHHHHHHHCCCCCEECCCCCCCHHHHCCCHHHHCCCCCCCCCCCC
TDPLYKHIPFTITQRSDISYGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDIDYYLF
CCCCHHCCCEEEEECCCCEEEEEHHCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEE
TGKQVLDVTKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEQHAIPC
CCCHHHHHHHHHHHHCCCEECCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCC
DSFQLSSGYTSINGKRYVFNWNYDKVPQPKVMSQSFHDAGLKLAANIKPCLLQDHPRYGE
CCEEECCCCEECCCCEEEEECCCCCCCCCHHHHCCHHHCCEEEECCCCCEEECCCCCHHH
VAERGLFIRDSQTDAPERSSFWDDEGSHLDFTNPQTVAWWQEGVTTQLLEMGIDSTWNDN
HHHCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCEEEHHHCCHHHHHHHHCCCCCCCCC
NEYEVWDGEARCYGFGREIAIKHIRPVMPLLMMRASLEAQQRFAPQKRPYLISRSGCAGM
CCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHH
QRYVQTWSGDNRTNWDTLRYNIRMGLGMSLSGLFNVGHDVGGFSGDKPEPELFVRWVQNG
HHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
VMHPRFTIHSWNDDQTVNEAWMYPAITPAIRSAIELRYRLLPYLYTLLWQAHADDEPMLR
CCCCEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTFLDHQHDAQTFAECDDFLLGRDLLVASVVEPGARQREVWLPDNQAGWYDFYSHQWFAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEECCCCCEECC
GQWVTLDAPLEKLPLLVRAGAGLPLSERISHVDAQKDDRRELQLFPLKGTGSTRGLLFED
CEEEEECCCHHHCCEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEC
DGESWGYKQGDALWLEWEMTCSASSINLDINARGNYRPAWKALKLSLPVGEKRKLLVNGV
CCCCCCCCCCCEEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEECC
EGTEWRL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]