| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
Click here to switch to the map view.
The map label for this gene is elsA [H]
Identifier: 238893824
GI number: 238893824
Start: 1696651
End: 1697373
Strand: Reverse
Name: elsA [H]
Synonym: KP1_1754
Alternate gene names: 238893824
Gene position: 1697373-1696651 (Counterclockwise)
Preceding gene: 238893825
Following gene: 238893819
Centisome position: 32.34
GC content: 61.69
Gene sequence:
>723_bases ATGTTGAATTTACAGGCAGTAAATCACTTTTACGGCAACCAGCATTCGCTGTGGAATGTCGATCTTGTACTACGCCCGGG AGAGTGCATTGGCGTACTGGGACGCGAGGGCATGGGAAAAACCACCCTGGTTAACTGCATTGCTGGCCACCTGCCGGTGG CTAGCGGCCGGATGACCTGGCATGACATTGGCGCCCCGCCGCAGGATCTCCCCCCCCTGTCCGCTCAATCGCGCAGCGCC ATTGGTATCGGCTACGTGCCACAAGATAAACGCATTTTTTCCCAACTCAGCGTGGAAGAGAACCTGCACATCGCCCTGGC GGCCGGGAAACCCGGGGCTAACGCCAGCGGCGGCGAGATTTATGAGCATTTTCCCGAGCTCTATGCCCTACGGCAGCGCA AAGGCGCCTCGCTGAGCGACGACGATCAGTACCAGCTGGCGCTGGCCAGGGCGCTGATCGTCCAGCCGCGGCTGCTGATC CTTGATGAACCCTCGCGCGGCAGAGGGCCGCGCTGCCTGCAAAAGCTGGCGGATCTGCTGCTGCGGTTAAATCGCGATAT CGGCCTGACGGTGCTGCTCGCCGAGCAGCACCTGCCCTTTATCCGCCGGGTGGCGGATCGCTTCTGTGTCTTGCACCGGG GCCGTAACGTCGCCGAAGGCGATATTATGGCGCTGGATGAGCCGCTGCTGGCGCAGTGGATAACGCCGGATCCAGCGCCC TGA
Upstream 100 bases:
>100_bases GTATCGGCGTTTAGCGCTTTTTTCCGAGCGTTCTTTTTCCTGGCAAGAGTTTTGCAGCATCTTTCTGTCGCCCTGACGCC AGGATAAGGAGAAAACGTCC
Downstream 100 bases:
>100_bases GGTCCAGATACTGGCCGAGATCGTCGCGCTGCGCGATGTCGGCAAGCCACGGTATTTCGCCGAGGAACGGCGCGGCCAGT CGGTTTTTCAGCGTCGCCAG
Product: putative amino acid transporter
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 240; Mature: 240
Protein sequence:
>240_residues MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTWHDIGAPPQDLPPLSAQSRSA IGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEIYEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLI LDEPSRGRGPRCLQKLADLLLRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP
Sequences:
>Translated_240_residues MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTWHDIGAPPQDLPPLSAQSRSA IGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEIYEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLI LDEPSRGRGPRCLQKLADLLLRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP >Mature_240_residues MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTWHDIGAPPQDLPPLSAQSRSA IGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEIYEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLI LDEPSRGRGPRCLQKLADLLLRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI150417984, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI105990541, Length=210, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI31657092, Length=209, Percent_Identity=26.7942583732057, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI27477115, Length=209, Percent_Identity=25.3588516746411, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI45446740, Length=204, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI47078218, Length=204, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI87082268, Length=237, Percent_Identity=32.4894514767932, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI1789864, Length=237, Percent_Identity=27.8481012658228, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789672, Length=223, Percent_Identity=27.3542600896861, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=31.4159292035398, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI48995001, Length=235, Percent_Identity=31.4893617021277, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1790190, Length=208, Percent_Identity=29.3269230769231, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1790525, Length=228, Percent_Identity=27.1929824561404, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787792, Length=240, Percent_Identity=30.4166666666667, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787712, Length=212, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1788761, Length=226, Percent_Identity=27.8761061946903, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1787370, Length=222, Percent_Identity=27.4774774774775, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786872, Length=224, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788225, Length=245, Percent_Identity=28.1632653061224, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787029, Length=229, Percent_Identity=26.6375545851528, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786703, Length=203, Percent_Identity=31.5270935960591, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787089, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1786253, Length=222, Percent_Identity=28.8288288288288, Blast_Score=74, Evalue=6e-15, Organism=Escherichia coli, GI48994943, Length=220, Percent_Identity=28.6363636363636, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI87081791, Length=225, Percent_Identity=24.4444444444444, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1786398, Length=216, Percent_Identity=26.3888888888889, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789991, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1790467, Length=218, Percent_Identity=27.9816513761468, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789891, Length=235, Percent_Identity=28.5106382978723, Blast_Score=67, Evalue=7e-13, Organism=Escherichia coli, GI1788450, Length=229, Percent_Identity=26.2008733624454, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787164, Length=218, Percent_Identity=29.3577981651376, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789873, Length=224, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1790544, Length=236, Percent_Identity=26.271186440678, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1786319, Length=244, Percent_Identity=26.6393442622951, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=26.2672811059908, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1788165, Length=215, Percent_Identity=27.906976744186, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1786653, Length=225, Percent_Identity=27.5555555555556, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI87081834, Length=210, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI87081782, Length=218, Percent_Identity=27.5229357798165, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1786563, Length=225, Percent_Identity=26.2222222222222, Blast_Score=61, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17565938, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI212646699, Length=217, Percent_Identity=28.110599078341, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17565586, Length=202, Percent_Identity=27.2277227722772, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71983523, Length=207, Percent_Identity=28.9855072463768, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71983516, Length=207, Percent_Identity=28.9855072463768, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71983510, Length=207, Percent_Identity=28.9855072463768, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI115533608, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6319856, Length=227, Percent_Identity=25.9911894273128, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24582014, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24582012, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI85725262, Length=184, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26390; Mature: 26390
Theoretical pI: Translated: 7.24; Mature: 7.24
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTW CCCHHHHHHHHCCCCCEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEE HDIGAPPQDLPPLSAQSRSAIGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEI EECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHH YEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLILDEPSRGRGPRCLQKLADLL HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHH LRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHCCCCCCCC >Mature Secondary Structure MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTW CCCHHHHHHHHCCCCCEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEE HDIGAPPQDLPPLSAQSRSAIGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEI EECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHH YEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLILDEPSRGRGPRCLQKLADLL HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHH LRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]