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The map label for this gene is bioC [H]

Identifier: 238893822

GI number: 238893822

Start: 1695203

End: 1695994

Strand: Direct

Name: bioC [H]

Synonym: KP1_1752

Alternate gene names: 238893822

Gene position: 1695203-1695994 (Clockwise)

Preceding gene: 238893821

Following gene: 238893823

Centisome position: 32.3

GC content: 66.41

Gene sequence:

>792_bases
ATGCTGAAGACATTAACCGTTTACTGGAGGTGCTGCATGGCCACAGTGAATAAGCAGGCGGTGGCCGCGGCGTTTGGCCG
GGCGGCCAGCGGCTATACGCAACATGATGAACTGCAGCGGCGCTGCGCCGATCTATTGCTGCGCCAGCTGGCGCGCCGCG
ATTTTGCGCAGGTGCTGGATGCCGGCTGCGGCCCCGGCAGTATGAGTCGCTATTGGCGTGAGGCGGGCAGCGTGGTGACC
GCGCTGGATCTCTCCGCCGGGATGCTCGCCCAGGCGCAGCGTAACGACGCCGCGCAGCATTATCTGCTGGGGGATATTGA
GGCGCTGCCGCTGCCGGACGCCTGCGTCGATCTGGCGTGGAGCAATCTGGCGGTGCAGTGGTGCGACGATCTACGGGCGG
CAATTGGCGAGCTGTACCGGGTGGCGCGTCCCGGCGGCAGAGTGGCGTTTAGCACGCTGCTCGCCGACTCGCTGCCGGAG
CTCAATCAGGCGTGGCAGGCCATCGACGACCGGCCGCATGCCAACCGTTTCCTTAGCGAAGCGGCGGTGCGCGCGGCGCT
TCGCGGCCTGCGCGCGACCGGCGAGGTTCATCAGATTAGCCTGCCGTTCGCCGATGCGCTGAGCGCTATGCGCTCGCTGA
AGGGCATCGGCGCCACCCATTTGCACCAGGGACGGACAGCCGCCCCGCTTGGCCGCGGCAAACTGCGCGAGCTGCAGCTG
GCCTGGCCGCAGCGGCAGGGCATCTGCCCGCTGACGTATTCTCTTTTTACAGGAGTCATTGAGCGTGACTAA

Upstream 100 bases:

>100_bases
TGCCGTCTACGCGACGCGGGCTGCTGGGCAACGGCGATCCGTCCGCCGACGGTGCCGGTCGGCAGCGCGCGTTTGCGCCT
GACCCTGACAGCCGCCCATC

Downstream 100 bases:

>100_bases
ACGTTTTTTTGTCACCGGGACCGATACTGAAGTCGGTAAAACCATCGCCAGCAGCGCCCTGCTGCAGGCGGCTAATCTGC
TGGGTTTTCACACTGCCGGC

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLKTLTVYWRCCMATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVT
ALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPE
LNQAWQAIDDRPHANRFLSEAAVRAALRGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQL
AWPQRQGICPLTYSLFTGVIERD

Sequences:

>Translated_263_residues
MLKTLTVYWRCCMATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVT
ALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPE
LNQAWQAIDDRPHANRFLSEAAVRAALRGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQL
AWPQRQGICPLTYSLFTGVIERD
>Mature_263_residues
MLKTLTVYWRCCMATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVT
ALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPE
LNQAWQAIDDRPHANRFLSEAAVRAALRGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQL
AWPQRQGICPLTYSLFTGVIERD

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=251, Percent_Identity=64.1434262948207, Blast_Score=300, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28736; Mature: 28736

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTLTVYWRCCMATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGCGPGSMSRYWREAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAW
CCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
AAVRAALRGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQL
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHH
AWPQRQGICPLTYSLFTGVIERD
CCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKTLTVYWRCCMATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGCGPGSMSRYWREAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAW
CCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
AAVRAALRGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQL
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHH
AWPQRQGICPLTYSLFTGVIERD
CCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]