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The map label for this gene is hpmB [H]

Identifier: 238893712

GI number: 238893712

Start: 1574727

End: 1576436

Strand: Reverse

Name: hpmB [H]

Synonym: KP1_1633

Alternate gene names: 238893712

Gene position: 1576436-1574727 (Counterclockwise)

Preceding gene: 238893713

Following gene: 238893711

Centisome position: 30.04

GC content: 56.96

Gene sequence:

>1710_bases
ATGCGCCACCAAACCAATGAAACAAATGGATATTGCTTCATGTTAATTCGATCTCGCACGCTCACCGGGCTGCTGTTTAT
CACGCTGGCGGGCACCTCAGCCGCCGGGGCCGCGCCATTGACCTCTTCTACTCACCAGACGGAGCAGGATAAAGCCCGCC
AGGAGGCGCTGGCGCCGCAGCAACAGGATTTTCAGTCTTCACAACAGCGCGTGGCGCCGCAGGGTATCCCTTTTCCTGAG
GAAACGCATTGCAAATTGATCAACCGGGTCGATATCGACTCCGATAACCAGGCGCTCACCCGGAAATTACTGGCGAAAAC
CGCGCGGCAGGCGCAGGGACGCTGCCTGGGCAGCGAAGGCATTCGCCTGCTGGCCTATACCTTGCAAAATGAGCTGATCG
CGCAAGGCTACATCACCTCGCTGATTGATGTGCCCTCCCAGTCGCTGGAGCACGGCATACTCAGGTTCACGCTGCACTAT
GGCAAAGTGGGCGCTATCGACTATGCCGACGGCTCGGACACCACCCGCCTGTGGAATTCCCTGCCCACCTCTTCCGGTAC
TATCCTGCGCTTAAGCGACCTTGAGCAAGGGATGGCCAACCTGCAGCGTCTGCCCGGCGCCACCGCGCACATGAAACTGC
TGCCGGGCCAACACGAGGGAGAAAGCGATATCCAGATCGCCCGCAGCCTGGCGAAAAAATGGCAGCTTGGCGCCTGGCTT
GACGACGCCGGCAGCAAAGCCAGCGGACGCTACCAGGCCGGCGGGGCCCTCTATCTCTATGACCTGACCACCCTCAACGA
TATCCTGTACCTTTCCGGCGGGGGCGATATTGAATTCAATCAGCATAACGACGGCAACCACAACGGCAGCCTGTATTACT
CCATTCCCTTTGGCTACTGGACACTAAGCGCCTACGGGGCATACAGCCAGTATCGTCAGCAGTTTAACGGCAACTGGTCG
ACGATGGATTATAAGAGTAAAAATCGCTACTACAGCGCCACGCTGAGTCGTCTGCTCTCCCACACCCGGCAGCAAAAAAC
CACCGCCGACCTGCGGATCGCCAAGAGTACCTCGCATTATTACTTCGGCGGCAGTGAGCTACTGGTGATGCGCAAGCAGA
ACCCCTCATGGGAATTCACCCTCAACCACCAGCACTACTTTAACAAAAAGATTGTTGATGCCAGCATCGGCATCCAGCGC
AGCCTGCCGTGGCTCAGCTCGACAGCAACGCCGGAAGAGCAGGCCGGGCTGTATAGCCCGCTGTCGCGGATTGTGCATGG
TAATCTGCAGGCAATGATGAAATTTGACGCCACCGGCGACAAATTTACCTGGGCTCCCCGCCTCAGCGCCCAGTTCAGCC
CGGACAAACTCGCTTCCGATAACAAATTCAATATTGGCAGCCGCTGGAGCGTGCGCGGTTTTGACGGTGAAAACAGCCTG
TCCGGCAATCAGGGATGGTACTGGCGCAACGATTTTATCTGGGATCTGGCCACCCACGAGCGGCAATTCTATTTGGGCGC
GGATATAGGCCGCCTTATCGGCGCCGATCTATATCAAAAAGGCAAAGTGCTCTCCGGCGCCGTCAGCGGGCTGCGCGGTC
AGCTATGGTCAACGCAGTACGATCTGTTTATTAGTACCCCGCTGAGTAAACCGGATAAGTTTCATAGCGACGCCCTGAAT
ATGGGCTTTTCATTACAGTGGAGGTATTAA

Upstream 100 bases:

>100_bases
TCGCACGATTATTTTATTAATTGAATATAATATTCTTGCCTGACCCCGCCTGCGCCGAAATAAAGGTCATCAATATTCTC
TGCCGCTCGCAGAATAATGG

Downstream 100 bases:

>100_bases
TTCGCACATTATTGACTCGTCATATTTACATTATTTATTAATCATTATTTAAAGGAATAAAGAAAATGTTTAAGTTTAAG
GCTTCTTATGTCGCACTGGC

Product: putative hemolysin activator HlyB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MRHQTNETNGYCFMLIRSRTLTGLLFITLAGTSAAGAAPLTSSTHQTEQDKARQEALAPQQQDFQSSQQRVAPQGIPFPE
ETHCKLINRVDIDSDNQALTRKLLAKTARQAQGRCLGSEGIRLLAYTLQNELIAQGYITSLIDVPSQSLEHGILRFTLHY
GKVGAIDYADGSDTTRLWNSLPTSSGTILRLSDLEQGMANLQRLPGATAHMKLLPGQHEGESDIQIARSLAKKWQLGAWL
DDAGSKASGRYQAGGALYLYDLTTLNDILYLSGGGDIEFNQHNDGNHNGSLYYSIPFGYWTLSAYGAYSQYRQQFNGNWS
TMDYKSKNRYYSATLSRLLSHTRQQKTTADLRIAKSTSHYYFGGSELLVMRKQNPSWEFTLNHQHYFNKKIVDASIGIQR
SLPWLSSTATPEEQAGLYSPLSRIVHGNLQAMMKFDATGDKFTWAPRLSAQFSPDKLASDNKFNIGSRWSVRGFDGENSL
SGNQGWYWRNDFIWDLATHERQFYLGADIGRLIGADLYQKGKVLSGAVSGLRGQLWSTQYDLFISTPLSKPDKFHSDALN
MGFSLQWRY

Sequences:

>Translated_569_residues
MRHQTNETNGYCFMLIRSRTLTGLLFITLAGTSAAGAAPLTSSTHQTEQDKARQEALAPQQQDFQSSQQRVAPQGIPFPE
ETHCKLINRVDIDSDNQALTRKLLAKTARQAQGRCLGSEGIRLLAYTLQNELIAQGYITSLIDVPSQSLEHGILRFTLHY
GKVGAIDYADGSDTTRLWNSLPTSSGTILRLSDLEQGMANLQRLPGATAHMKLLPGQHEGESDIQIARSLAKKWQLGAWL
DDAGSKASGRYQAGGALYLYDLTTLNDILYLSGGGDIEFNQHNDGNHNGSLYYSIPFGYWTLSAYGAYSQYRQQFNGNWS
TMDYKSKNRYYSATLSRLLSHTRQQKTTADLRIAKSTSHYYFGGSELLVMRKQNPSWEFTLNHQHYFNKKIVDASIGIQR
SLPWLSSTATPEEQAGLYSPLSRIVHGNLQAMMKFDATGDKFTWAPRLSAQFSPDKLASDNKFNIGSRWSVRGFDGENSL
SGNQGWYWRNDFIWDLATHERQFYLGADIGRLIGADLYQKGKVLSGAVSGLRGQLWSTQYDLFISTPLSKPDKFHSDALN
MGFSLQWRY
>Mature_569_residues
MRHQTNETNGYCFMLIRSRTLTGLLFITLAGTSAAGAAPLTSSTHQTEQDKARQEALAPQQQDFQSSQQRVAPQGIPFPE
ETHCKLINRVDIDSDNQALTRKLLAKTARQAQGRCLGSEGIRLLAYTLQNELIAQGYITSLIDVPSQSLEHGILRFTLHY
GKVGAIDYADGSDTTRLWNSLPTSSGTILRLSDLEQGMANLQRLPGATAHMKLLPGQHEGESDIQIARSLAKKWQLGAWL
DDAGSKASGRYQAGGALYLYDLTTLNDILYLSGGGDIEFNQHNDGNHNGSLYYSIPFGYWTLSAYGAYSQYRQQFNGNWS
TMDYKSKNRYYSATLSRLLSHTRQQKTTADLRIAKSTSHYYFGGSELLVMRKQNPSWEFTLNHQHYFNKKIVDASIGIQR
SLPWLSSTATPEEQAGLYSPLSRIVHGNLQAMMKFDATGDKFTWAPRLSAQFSPDKLASDNKFNIGSRWSVRGFDGENSL
SGNQGWYWRNDFIWDLATHERQFYLGADIGRLIGADLYQKGKVLSGAVSGLRGQLWSTQYDLFISTPLSKPDKFHSDALN
MGFSLQWRY

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 63751; Mature: 63751

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHQTNETNGYCFMLIRSRTLTGLLFITLAGTSAAGAAPLTSSTHQTEQDKARQEALAPQ
CCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
QQDFQSSQQRVAPQGIPFPEETHCKLINRVDIDSDNQALTRKLLAKTARQAQGRCLGSEG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
IRLLAYTLQNELIAQGYITSLIDVPSQSLEHGILRFTLHYGKVGAIDYADGSDTTRLWNS
CEEEEEHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCEEEEECCCCCCHHHHHHC
LPTSSGTILRLSDLEQGMANLQRLPGATAHMKLLPGQHEGESDIQIARSLAKKWQLGAWL
CCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEE
DDAGSKASGRYQAGGALYLYDLTTLNDILYLSGGGDIEFNQHNDGNHNGSLYYSIPFGYW
CCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCEEEEEECCCEE
TLSAYGAYSQYRQQFNGNWSTMDYKSKNRYYSATLSRLLSHTRQQKTTADLRIAKSTSHY
EHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCEE
YFGGSELLVMRKQNPSWEFTLNHQHYFNKKIVDASIGIQRSLPWLSSTATPEEQAGLYSP
EECCCEEEEEEECCCCEEEEECCHHHCCCEEEEHHCCCHHCCCCCCCCCCCHHHCCHHHH
LSRIVHGNLQAMMKFDATGDKFTWAPRLSAQFSPDKLASDNKFNIGSRWSVRGFDGENSL
HHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCC
SGNQGWYWRNDFIWDLATHERQFYLGADIGRLIGADLYQKGKVLSGAVSGLRGQLWSTQY
CCCCCEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEE
DLFISTPLSKPDKFHSDALNMGFSLQWRY
EEEEECCCCCCCHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MRHQTNETNGYCFMLIRSRTLTGLLFITLAGTSAAGAAPLTSSTHQTEQDKARQEALAPQ
CCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
QQDFQSSQQRVAPQGIPFPEETHCKLINRVDIDSDNQALTRKLLAKTARQAQGRCLGSEG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
IRLLAYTLQNELIAQGYITSLIDVPSQSLEHGILRFTLHYGKVGAIDYADGSDTTRLWNS
CEEEEEHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCEEEEECCCCCCHHHHHHC
LPTSSGTILRLSDLEQGMANLQRLPGATAHMKLLPGQHEGESDIQIARSLAKKWQLGAWL
CCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEE
DDAGSKASGRYQAGGALYLYDLTTLNDILYLSGGGDIEFNQHNDGNHNGSLYYSIPFGYW
CCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCEEEEEECCCEE
TLSAYGAYSQYRQQFNGNWSTMDYKSKNRYYSATLSRLLSHTRQQKTTADLRIAKSTSHY
EHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCEE
YFGGSELLVMRKQNPSWEFTLNHQHYFNKKIVDASIGIQRSLPWLSSTATPEEQAGLYSP
EECCCEEEEEEECCCCEEEEECCHHHCCCEEEEHHCCCHHCCCCCCCCCCCHHHCCHHHH
LSRIVHGNLQAMMKFDATGDKFTWAPRLSAQFSPDKLASDNKFNIGSRWSVRGFDGENSL
HHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCHHCCCCCCCCCCCEEEEECCCCCCCC
SGNQGWYWRNDFIWDLATHERQFYLGADIGRLIGADLYQKGKVLSGAVSGLRGQLWSTQY
CCCCCEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEE
DLFISTPLSKPDKFHSDALNMGFSLQWRY
EEEEECCCCCCCHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]