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The map label for this gene is shlA [H]

Identifier: 238893711

GI number: 238893711

Start: 1572868

End: 1574661

Strand: Reverse

Name: shlA [H]

Synonym: KP1_1632

Alternate gene names: 238893711

Gene position: 1574661-1572868 (Counterclockwise)

Preceding gene: 238893712

Following gene: 238893709

Centisome position: 30.0

GC content: 52.56

Gene sequence:

>1794_bases
ATGTTTAAGTTTAAGGCTTCTTATGTCGCACTGGCGGCAGTATTAACCTCGTCGGTAGTTTATGCCGACCCCACAAGCTA
TACGCACTCTTCCGGCGCCACGGTTATCGATATTGAAAAGCCGAACGCCGCCGGTGTCTCCCATAACCTGTACCGCGACT
TCAACGTCGGCGCCAATGGCACCATCCTCAATAACAGCGGCGATGATGTCAGCCACAGCACATTTGGCAATATCGCCCGC
AACAATAATCTGACCGCCGGCAGCGCTTCGGTGATTTTGAACGAGGTGACCTCCAAAAACGCCAGTAGCCTGAAGGGCTT
TATCGAAGTCAACGGTCAGAAAGCGGATGTGGTAATCGCCAACCCGAACGGCATCACCTGTTCCGGCTGTAGCTTTGTTA
ATACCAACAAGGCTATCCTGACCACCGGCAAGGTTAATATGACCGACGATGGCGCTATCGGCAGCTATACCGTAACGGGC
GGCACCCTCACCATCGGCGAAAATGGCATGAACGCCGCCAACGGCTATGCGGTTCTGCTCGCCGACGCGATCAATATCAA
CGGTAAAGTGCAGGCCAACAACGCCCTGGTCAGCGCGGGCAACTTCACCATGGATAACAGCTCTGGCTCGGTGACCTCCG
CTGGTAAAAAGGCCACCCTGATCCAGATGACGGTTAACCCGCAGTACAGCATCGACGTCAGCAGCCTTGGCGGCATTGAG
GCCAACAGCATCAGCATGGTCGGCAATAACATCGGCTTTGGCGTACGTAATAAAGGCTCTATCGTCGCGAATAGTTCGCT
GCAGCTCACCAGCAACGGTAATCTGCTGAACAAAGGCACGATCAAAAGCAACGGTCTGCTGAGTCAGGTCGCCACCGCCT
CGGGCATCACCAATGACGGTAGCATCGCCGGCGCCTATTATTTAATGCTCTCCAGTGGCGATTATATCGTTAACACCGGT
TCTCTCTCCGGCGGCCAGCTGATTGCCACCGCTAACGGCAACATCACCAACGGCGACTCAGGCACGATGACCGGCACCAG
TGGATTAAGCCTGACCAGCGGCGGGAAAATCCGCAACGAAGAAAAAGCCTCCCTGCTGTCAAATAACCAGATTGCCGCCA
CGGCAATCGGTGATTTCCTCAATGAAGGCAAAATCAGCGCCAAACACACCAGCCTGACGTTTGTCGGCGACAGCTTTAAA
AACACTGGCAATATTAACTCTACTGGCCAAACCACCATTCAGTCGCTTAAACAGGACGGCAGCGCCAATACGGGCGAGAT
CTATAACCTCGGCAATATCACCGGCGAAAATATCAATCTGCAGACCAATGGCACGCTGGCGCAAAGCAGCAGTGGTCGTA
TTGAGGCAACCAACGCCATTACCGCCCACAGCTACTGGCTGAACCAAAATGGTTATATGAATGCCGCCGATATCACCACC
GATCACGGCGTAGTGAATAATTATGGCAATATTACTGCCAAAAATATTTCAATCACGACCTACTCAGATATCACCAACGA
AGGGCAGATCAGCAGCACCGGCGACCTGACCTTAAATACCAAAAATAAAGGCGCGATCTACAATTATTCAACCCTCAGCG
CGGGCGGCAACATGACGTTAACCGCCACCAAAGTGGTCAATGGTGGTAAAAGTTGCGGCATACTGGGCCTGGCGAAATGC
GGCGTCGGGACGTTAACTGCTGACAAGCTGGTACTGAACTCATCGCAGAAATATGTTAGCGACATGGGTGGAAAACAGTA
TTTCAAGAGCACCGAAGTCAACACGGTGAAATAA

Upstream 100 bases:

>100_bases
TGAATATGGGCTTTTCATTACAGTGGAGGTATTAATTCGCACATTATTGACTCGTCATATTTACATTATTTATTAATCAT
TATTTAAAGGAATAAAGAAA

Downstream 100 bases:

>100_bases
GACAAACCACGATGCGCGAAGCCTCGCGCATCGTTTTTCGCACGCTTAGGGCTCGAAGGGCCGACGCTGGAACTGATCGT
GGCCACATTTTGGACAGCGC

Product: putative Filamentous haemagglutinin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MFKFKASYVALAAVLTSSVVYADPTSYTHSSGATVIDIEKPNAAGVSHNLYRDFNVGANGTILNNSGDDVSHSTFGNIAR
NNNLTAGSASVILNEVTSKNASSLKGFIEVNGQKADVVIANPNGITCSGCSFVNTNKAILTTGKVNMTDDGAIGSYTVTG
GTLTIGENGMNAANGYAVLLADAININGKVQANNALVSAGNFTMDNSSGSVTSAGKKATLIQMTVNPQYSIDVSSLGGIE
ANSISMVGNNIGFGVRNKGSIVANSSLQLTSNGNLLNKGTIKSNGLLSQVATASGITNDGSIAGAYYLMLSSGDYIVNTG
SLSGGQLIATANGNITNGDSGTMTGTSGLSLTSGGKIRNEEKASLLSNNQIAATAIGDFLNEGKISAKHTSLTFVGDSFK
NTGNINSTGQTTIQSLKQDGSANTGEIYNLGNITGENINLQTNGTLAQSSSGRIEATNAITAHSYWLNQNGYMNAADITT
DHGVVNNYGNITAKNISITTYSDITNEGQISSTGDLTLNTKNKGAIYNYSTLSAGGNMTLTATKVVNGGKSCGILGLAKC
GVGTLTADKLVLNSSQKYVSDMGGKQYFKSTEVNTVK

Sequences:

>Translated_597_residues
MFKFKASYVALAAVLTSSVVYADPTSYTHSSGATVIDIEKPNAAGVSHNLYRDFNVGANGTILNNSGDDVSHSTFGNIAR
NNNLTAGSASVILNEVTSKNASSLKGFIEVNGQKADVVIANPNGITCSGCSFVNTNKAILTTGKVNMTDDGAIGSYTVTG
GTLTIGENGMNAANGYAVLLADAININGKVQANNALVSAGNFTMDNSSGSVTSAGKKATLIQMTVNPQYSIDVSSLGGIE
ANSISMVGNNIGFGVRNKGSIVANSSLQLTSNGNLLNKGTIKSNGLLSQVATASGITNDGSIAGAYYLMLSSGDYIVNTG
SLSGGQLIATANGNITNGDSGTMTGTSGLSLTSGGKIRNEEKASLLSNNQIAATAIGDFLNEGKISAKHTSLTFVGDSFK
NTGNINSTGQTTIQSLKQDGSANTGEIYNLGNITGENINLQTNGTLAQSSSGRIEATNAITAHSYWLNQNGYMNAADITT
DHGVVNNYGNITAKNISITTYSDITNEGQISSTGDLTLNTKNKGAIYNYSTLSAGGNMTLTATKVVNGGKSCGILGLAKC
GVGTLTADKLVLNSSQKYVSDMGGKQYFKSTEVNTVK
>Mature_597_residues
MFKFKASYVALAAVLTSSVVYADPTSYTHSSGATVIDIEKPNAAGVSHNLYRDFNVGANGTILNNSGDDVSHSTFGNIAR
NNNLTAGSASVILNEVTSKNASSLKGFIEVNGQKADVVIANPNGITCSGCSFVNTNKAILTTGKVNMTDDGAIGSYTVTG
GTLTIGENGMNAANGYAVLLADAININGKVQANNALVSAGNFTMDNSSGSVTSAGKKATLIQMTVNPQYSIDVSSLGGIE
ANSISMVGNNIGFGVRNKGSIVANSSLQLTSNGNLLNKGTIKSNGLLSQVATASGITNDGSIAGAYYLMLSSGDYIVNTG
SLSGGQLIATANGNITNGDSGTMTGTSGLSLTSGGKIRNEEKASLLSNNQIAATAIGDFLNEGKISAKHTSLTFVGDSFK
NTGNINSTGQTTIQSLKQDGSANTGEIYNLGNITGENINLQTNGTLAQSSSGRIEATNAITAHSYWLNQNGYMNAADITT
DHGVVNNYGNITAKNISITTYSDITNEGQISSTGDLTLNTKNKGAIYNYSTLSAGGNMTLTATKVVNGGKSCGILGLAKC
GVGTLTADKLVLNSSQKYVSDMGGKQYFKSTEVNTVK

Specific function: Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane. ShlA requires shlB function [H]

COG id: COG3210

COG function: function code U; Large exoproteins involved in heme utilization or adhesion

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010069
- InterPro:   IPR008638
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011102 [H]

Pfam domain/function: PF05860 Haemagg_act [H]

EC number: NA

Molecular weight: Translated: 61158; Mature: 61158

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFKASYVALAAVLTSSVVYADPTSYTHSSGATVIDIEKPNAAGVSHNLYRDFNVGANG
CEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCC
TILNNSGDDVSHSTFGNIARNNNLTAGSASVILNEVTSKNASSLKGFIEVNGQKADVVIA
EEECCCCCCCCCCCCCCHHCCCCCCCCCHHEEEEHHHCCCHHHCEEEEEECCCEEEEEEE
NPNGITCSGCSFVNTNKAILTTGKVNMTDDGAIGSYTVTGGTLTIGENGMNAANGYAVLL
CCCCEEECCCEEECCCEEEEEECEEEECCCCCCCEEEEECCEEEECCCCCCCCCCEEEEE
ADAININGKVQANNALVSAGNFTMDNSSGSVTSAGKKATLIQMTVNPQYSIDVSSLGGIE
EEEECCCCEEEECCEEEECCCEEEECCCCCEECCCCEEEEEEEEECCCEEEEHHHCCCCC
ANSISMVGNNIGFGVRNKGSIVANSSLQLTSNGNLLNKGTIKSNGLLSQVATASGITNDG
CCEEEEECCCCCCCCCCCCCEEECCEEEEECCCCEEECCCCCCCCHHHHHHHHCCCCCCC
SIAGAYYLMLSSGDYIVNTGSLSGGQLIATANGNITNGDSGTMTGTSGLSLTSGGKIRNE
CEEEEEEEEEECCCEEEEECCCCCCEEEEECCCCEECCCCCCEECCCCCEECCCCCCCCC
EKASLLSNNQIAATAIGDFLNEGKISAKHTSLTFVGDSFKNTGNINSTGQTTIQSLKQDG
HHHHHHCCCCEEEEEHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCC
SANTGEIYNLGNITGENINLQTNGTLAQSSSGRIEATNAITAHSYWLNQNGYMNAADITT
CCCCCCEEECCCCCCCEEEEEECCCEEECCCCCEEEECEEEEEEEEECCCCEEEECCCCC
DHGVVNNYGNITAKNISITTYSDITNEGQISSTGDLTLNTKNKGAIYNYSTLSAGGNMTL
CCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCEEE
TATKVVNGGKSCGILGLAKCGVGTLTADKLVLNSSQKYVSDMGGKQYFKSTEVNTVK
EEEEEECCCCCCCEEEECCCCCCCEEECEEEECCCHHHHHHCCCHHHCCCCCCEECC
>Mature Secondary Structure
MFKFKASYVALAAVLTSSVVYADPTSYTHSSGATVIDIEKPNAAGVSHNLYRDFNVGANG
CEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCC
TILNNSGDDVSHSTFGNIARNNNLTAGSASVILNEVTSKNASSLKGFIEVNGQKADVVIA
EEECCCCCCCCCCCCCCHHCCCCCCCCCHHEEEEHHHCCCHHHCEEEEEECCCEEEEEEE
NPNGITCSGCSFVNTNKAILTTGKVNMTDDGAIGSYTVTGGTLTIGENGMNAANGYAVLL
CCCCEEECCCEEECCCEEEEEECEEEECCCCCCCEEEEECCEEEECCCCCCCCCCEEEEE
ADAININGKVQANNALVSAGNFTMDNSSGSVTSAGKKATLIQMTVNPQYSIDVSSLGGIE
EEEECCCCEEEECCEEEECCCEEEECCCCCEECCCCEEEEEEEEECCCEEEEHHHCCCCC
ANSISMVGNNIGFGVRNKGSIVANSSLQLTSNGNLLNKGTIKSNGLLSQVATASGITNDG
CCEEEEECCCCCCCCCCCCCEEECCEEEEECCCCEEECCCCCCCCHHHHHHHHCCCCCCC
SIAGAYYLMLSSGDYIVNTGSLSGGQLIATANGNITNGDSGTMTGTSGLSLTSGGKIRNE
CEEEEEEEEEECCCEEEEECCCCCCEEEEECCCCEECCCCCCEECCCCCEECCCCCCCCC
EKASLLSNNQIAATAIGDFLNEGKISAKHTSLTFVGDSFKNTGNINSTGQTTIQSLKQDG
HHHHHHCCCCEEEEEHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCC
SANTGEIYNLGNITGENINLQTNGTLAQSSSGRIEATNAITAHSYWLNQNGYMNAADITT
CCCCCCEEECCCCCCCEEEEEECCCEEECCCCCEEEECEEEEEEEEECCCCEEEECCCCC
DHGVVNNYGNITAKNISITTYSDITNEGQISSTGDLTLNTKNKGAIYNYSTLSAGGNMTL
CCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCEEE
TATKVVNGGKSCGILGLAKCGVGTLTADKLVLNSSQKYVSDMGGKQYFKSTEVNTVK
EEEEEECCCCCCCEEEECCCCCCCEEECEEEECCCHHHHHHCCCHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]