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The map label for this gene is phpB [H]

Identifier: 238893705

GI number: 238893705

Start: 1566550

End: 1567179

Strand: Reverse

Name: phpB [H]

Synonym: KP1_1625

Alternate gene names: 238893705

Gene position: 1567179-1566550 (Counterclockwise)

Preceding gene: 238893706

Following gene: 238893704

Centisome position: 29.86

GC content: 62.06

Gene sequence:

>630_bases
ATGAAATTGTGGTTAGTTCGCCATGGCGAAACCGAAGCCAACGTTGCCGGGTTATACAGCGGCCATGCCCCAACGCCCCT
GACGCCGCGCGGCGTCGCTCAGGCGCGCGCGCTCGGCGAACGACTGCGCCTGGCGCCTTTCGATAAAGTATTCTGTAGCG
AGCTGGCGCGGACCGGGACAACGGCCGATCTGCTGCTTGGCGACCGCGCTATTCCGCGTGAGCGCCATCCCGCGCTCAAT
GAGATGTTTTTCGGCGACTGGGAGATGCGTCATCATCGCGACCTCCAGCGAGAAGATGCGGAAAACTATGCCGCCTGGTG
TGCCGACTGGCAGCATGCGGCCCCCACCAACGGCGAAAGCTTTCAGAATTTTGCCCGCCGCGTCAGCGAGTTTATCCCAA
CGCTGACCGACTGCCGCCATCTTGACCATCTGCTGATCGTCGGCCATCAGGGCGTCCTGAGCCTGCTGACCGCCCTGCTG
TTGCAGATGCCTCCGGCGGCGATGTGGCACTTTCCCATTGCCCATGGCGCCTGGAGCCTCCTCGAAATCCGCGACGATTT
CACCACCCTGCGGGTATTAAATAGCCAGGCCGTCTGGCGGCCGCAAGAAGAATTCCCGCCAGACCATTGA

Upstream 100 bases:

>100_bases
CATCCGCGAGCAGGGACTCTATTGCTGACCCCAGGCTGGGCCTGGCGCGAAAAAAGCGCTATCGTAACGCCATCTCTTCA
TCGCCTGTCAGAGCCTGTTC

Downstream 100 bases:

>100_bases
CAGGCCAGAGCAGGCTGTTATTCTCCGCTGCCAGGCAGCATCCGCCAAAGCCGGTTTGCAGAAATTGTTTTACAAAAATG
GCGATGCAATCCGCGGCGAG

Product: alpha ribazole-5'-P phosphatase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKLWLVRHGETEANVAGLYSGHAPTPLTPRGVAQARALGERLRLAPFDKVFCSELARTGTTADLLLGDRAIPRERHPALN
EMFFGDWEMRHHRDLQREDAENYAAWCADWQHAAPTNGESFQNFARRVSEFIPTLTDCRHLDHLLIVGHQGVLSLLTALL
LQMPPAAMWHFPIAHGAWSLLEIRDDFTTLRVLNSQAVWRPQEEFPPDH

Sequences:

>Translated_209_residues
MKLWLVRHGETEANVAGLYSGHAPTPLTPRGVAQARALGERLRLAPFDKVFCSELARTGTTADLLLGDRAIPRERHPALN
EMFFGDWEMRHHRDLQREDAENYAAWCADWQHAAPTNGESFQNFARRVSEFIPTLTDCRHLDHLLIVGHQGVLSLLTALL
LQMPPAAMWHFPIAHGAWSLLEIRDDFTTLRVLNSQAVWRPQEEFPPDH
>Mature_209_residues
MKLWLVRHGETEANVAGLYSGHAPTPLTPRGVAQARALGERLRLAPFDKVFCSELARTGTTADLLLGDRAIPRERHPALN
EMFFGDWEMRHHRDLQREDAENYAAWCADWQHAAPTNGESFQNFARRVSEFIPTLTDCRHLDHLLIVGHQGVLSLLTALL
LQMPPAAMWHFPIAHGAWSLLEIRDDFTTLRVLNSQAVWRPQEEFPPDH

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=198, Percent_Identity=61.6161616161616, Blast_Score=261, Evalue=3e-71,
Organism=Escherichia coli, GI1790856, Length=165, Percent_Identity=27.8787878787879, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324857, Length=172, Percent_Identity=30.8139534883721, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 23783; Mature: 23783

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWLVRHGETEANVAGLYSGHAPTPLTPRGVAQARALGERLRLAPFDKVFCSELARTGT
CEEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
TADLLLGDRAIPRERHPALNEMFFGDWEMRHHRDLQREDAENYAAWCADWQHAAPTNGES
CHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
FQNFARRVSEFIPTLTDCRHLDHLLIVGHQGVLSLLTALLLQMPPAAMWHFPIAHGAWSL
HHHHHHHHHHHCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCHHHHHCCHHHCCHHH
LEIRDDFTTLRVLNSQAVWRPQEEFPPDH
HHHHHHHHHHHHHCCCCCCCCHHCCCCCC
>Mature Secondary Structure
MKLWLVRHGETEANVAGLYSGHAPTPLTPRGVAQARALGERLRLAPFDKVFCSELARTGT
CEEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
TADLLLGDRAIPRERHPALNEMFFGDWEMRHHRDLQREDAENYAAWCADWQHAAPTNGES
CHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
FQNFARRVSEFIPTLTDCRHLDHLLIVGHQGVLSLLTALLLQMPPAAMWHFPIAHGAWSL
HHHHHHHHHHHCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCHHHHHCCHHHCCHHH
LEIRDDFTTLRVLNSQAVWRPQEEFPPDH
HHHHHHHHHHHHHCCCCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]