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The map label for this gene is lyx [H]

Identifier: 238893668

GI number: 238893668

Start: 1529960

End: 1531456

Strand: Direct

Name: lyx [H]

Synonym: KP1_1586

Alternate gene names: 238893668

Gene position: 1529960-1531456 (Clockwise)

Preceding gene: 238893667

Following gene: 238893669

Centisome position: 29.15

GC content: 67.2

Gene sequence:

>1497_bases
ATGGATTTTTATCTTGGGATCGATATCGGCACCTCGCGGGTGAAAGCGGTGCTGTTTGATCAGCATTTCACCGCCTGCGC
CAGCGCCGCGGAAAACACCTCACCCCGCCTGTCGGCCAATGGCTACGCGGAACAGGATATGACCCAGCTGTGGCATTCGG
TGCTGGCTATTCTGCGCCAGATTGCCCGCCACCCGGCGCTCCAGGCGGGGCGGCTGCGGGCTATCGGCCTCGCCGGGCAA
GGGGAGGGGGTCTGGCTCAGCGATGAGCAGGGCGAACCGGTGGGCCCGGGGATCCTGTGGAGCGATACCCGTAGCCACGA
GCTGATGAGCGACCTGCTGCGCCGACCCGGCTTCGACCGCCGCTATTTCGCCGATACCGGCACCCACCTGCAGCCCTGCA
ATACCAGCCTGCAGCTGTACTGGCTGAAACAGTATCAGCCGGCGCGGCTGGCGGCCGCGCGCTATCTGTTTTTCGCCAAG
GACTGGATCCGCTTTCGCCTGACCGGCGTGGCGGCGCTGGAGCTGACGGACGCCAGCAGCTCGTTACTCAATCAGCAGAC
CGGCAGCTGGTCCTCGGTGGTGATGAACGAGATGGGGCTGAACGAACTGCTGCCGCTGTTTCCCCCGCTGCTGGCCCCGG
ATGCCCTGGCCGGCACGCTGAGCGACGCGGTGGCGGCGCTGACCGGGCTGCCCGCCGCGACGCCGGTGGCCGCCGGGGCG
CTGGATGTCTGTAGCGCCGCGCTGGGCTGCGGCGCGGTCAACGAAGGGGATATCTACACGATCCTCGGCACCACCTGCTG
CACCGGGATCGTCTGCCGCGGCCCGCAGACGGTGAACGAGGCGACGCGCTTTGTCACCCATACCGAAGCCGGACAGGTGA
TCTCCCTGTTTCCGATGCAGGCCGGTACGCCAAACATTGACTGGCTGCAGCAGCATATTTCGCTAGACGCCGATCTGGGG
CGCCTGGAGCAGGCGATCGCGGCGGTGGAGCCAGGCAGCGGCGGCGTCTTCTGGCAGCCGTACCTCAATGGCGAACGTGC
GCCGTTTTACAGCCCGGACGCGCGGGCCGGCTTTTTCGGCATTAGCCCGCACACCACCCGCGCCGAACTGCAGCGCGCGG
TGTTTGAAGGCCTGGCCTTCGCCATTGTCGATGCGCTGCAGGGTTATCCGCAGGGCGGCGAGCTGTATCTGACCGGCGGC
GGCGCAGCCTCGGCGACCTGGCTGCAGATTATCGCCGACTGTACCGGACGCACGGTGGTCTCCAGCGCCTTTAACGAACT
GAGCGCGCGCGGCGCGGCGATCCTGGCGGCCCGTAGCGTCGCGGCGCTGGCCGAGACGCCTCCGCTGGCGCAGACCCGCT
ATCAGCCGCGCCCTCAGGCGCATGCCCGCTACGCGGCGCTGTATCCCGTTTACCGCCTGCTGCGCGAGCAGATGCTGCCG
GTATGGCAGGCCAGACAGGCCGCCCTTCAACCTCTTTCTCAGGACCTACAACCATGA

Upstream 100 bases:

>100_bases
GAAAGATATTCAGGAGGCCCGCCGTCAACTGGAGGGGCTGGAGTTCCTGTTCGAGTGCGAGCTGATGCGCCGCCGCTACG
AGCCCTGAGCCGGAGCAGGT

Downstream 100 bases:

>100_bases
AAATCGTTTTTACCGCCGAGCATGCTGGCGACCTTAGCGCCTTCCACCAGCTGGGCGAGCTGCTGGTGGAGGGGTGGGCG
CTGGGCAAACCGAAACTCAG

Product: putative carbohydrate kinase

Products: NA

Alternate protein names: L-xylulokinase [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQIARHPALQAGRLRAIGLAGQ
GEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDRRYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAK
DWIRFRLTGVAALELTDASSSLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDALAGTLSDAVAALTGLPAATPVAAGA
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQAGTPNIDWLQQHISLDADLG
RLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFGISPHTTRAELQRAVFEGLAFAIVDALQGYPQGGELYLTGG
GAASATWLQIIADCTGRTVVSSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
VWQARQAALQPLSQDLQP

Sequences:

>Translated_498_residues
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQIARHPALQAGRLRAIGLAGQ
GEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDRRYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAK
DWIRFRLTGVAALELTDASSSLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDALAGTLSDAVAALTGLPAATPVAAGA
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQAGTPNIDWLQQHISLDADLG
RLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFGISPHTTRAELQRAVFEGLAFAIVDALQGYPQGGELYLTGG
GAASATWLQIIADCTGRTVVSSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
VWQARQAALQPLSQDLQP
>Mature_498_residues
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQIARHPALQAGRLRAIGLAGQ
GEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDRRYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAK
DWIRFRLTGVAALELTDASSSLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDALAGTLSDAVAALTGLPAATPVAAGA
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQAGTPNIDWLQQHISLDADLG
RLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFGISPHTTRAELQRAVFEGLAFAIVDALQGYPQGGELYLTGG
GAASATWLQIIADCTGRTVVSSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
VWQARQAALQPLSQDLQP

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=515, Percent_Identity=22.5242718446602, Blast_Score=103, Evalue=5e-22,
Organism=Escherichia coli, GI1790005, Length=497, Percent_Identity=29.7786720321932, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1789987, Length=495, Percent_Identity=29.4949494949495, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1789168, Length=493, Percent_Identity=27.5862068965517, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790361, Length=490, Percent_Identity=23.6734693877551, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787789, Length=500, Percent_Identity=25.4, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790338, Length=503, Percent_Identity=22.6640159045726, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=500, Percent_Identity=24, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17864214, Length=470, Percent_Identity=23.8297872340426, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24654573, Length=393, Percent_Identity=24.6819338422392, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.53 [H]

Molecular weight: Translated: 53583; Mature: 53583

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQ
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IARHPALQAGRLRAIGLAGQGEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDR
HHHCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCC
RYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAKDWIRFRLTGVAALELTDASS
EEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCHH
SLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDALAGTLSDAVAALTGLPAATPVAAGA
HHHHHCCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQ
HHHHHHHHCCCCCCCCCEEEEEHHHHHCCEEECCCCHHHHHHHHHEECCCCCEEEEEECC
AGTPNIDWLQQHISLDADLGRLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEC
ISPHTTRAELQRAVFEGLAFAIVDALQGYPQGGELYLTGGGAASATWLQIIADCTGRTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHH
SSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
VWQARQAALQPLSQDLQP
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQ
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IARHPALQAGRLRAIGLAGQGEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDR
HHHCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCC
RYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAKDWIRFRLTGVAALELTDASS
EEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCHH
SLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDALAGTLSDAVAALTGLPAATPVAAGA
HHHHHCCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQ
HHHHHHHHCCCCCCCCCEEEEEHHHHHCCEEECCCCHHHHHHHHHEECCCCCEEEEEECC
AGTPNIDWLQQHISLDADLGRLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEC
ISPHTTRAELQRAVFEGLAFAIVDALQGYPQGGELYLTGGGAASATWLQIIADCTGRTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHH
SSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
VWQARQAALQPLSQDLQP
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]