| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is entA [H]
Identifier: 238893646
GI number: 238893646
Start: 1505961
End: 1506746
Strand: Direct
Name: entA [H]
Synonym: KP1_1560
Alternate gene names: 238893646
Gene position: 1505961-1506746 (Clockwise)
Preceding gene: 238893645
Following gene: 238893647
Centisome position: 28.69
GC content: 65.27
Gene sequence:
>786_bases GTGGGCGCTGCTCACCCGCGAGGTGCAATAATGGCGGCGCTGGATTTTCACGGCCAGACCGTGTGGGTGACCGGCGCAGG TAAAGGGATTGGCTATGCCACCGCGCTGGCTTTCGTCGAGGCCGGGGCCAACGTCACCGGGTTCGACCTCGCCTTTGACG GCGAAAGCTACCCGTTTGCCACCGAAACGCTGGACGTTGCCGATGCCGACCAGGTACGCGAGGCATGCAGCCGGCTGTTG GCGAACACCGAGCGTTTAGATGTGCTGGTGAACGCCGCCGGGATCCTGCGCATGGGCGCTACCGACCAGCTGAGCGCGGA AGACTGGCAGCAGACCTTCGCGGTCAACGTCGGCGGCGCGTTTAATCTGTTTCAGCAGACGATGGCCCAGTTCCGTCGCC AGCGGGGCGGGGCGATCGTCACCGTCGCCTCCGATGCCGCGCACACGCCGCGCATCGGCATGAGCGCCTATGGCGCCTCG AAGGCGGCGCTGAAAAGCCTGGCGCTGACCGTCGGCCTTGAGCTGGCGGGCTGCGGGGTGCGCTGTAATCTGGTGTCGCC GGGCTCCACCGATACCGATATGCAGCGCACCCTGTGGGTCAGCGACGATGCAGAGCAGCAGCGGATCCGCGGCTTCGGCG AGCAGTTTAAGCTCGGCATCCCGCTGGGTAAAATCGCCCGCCCGCAGGAGATCGCCAATACCATTCTGTTCCTCGCCTCT TCTCACGCCAGCCATATCACCCTGCAGGATATCGTGGTTGATGGCGGCTCGACGCTGGGGGCGTAA
Upstream 100 bases:
>100_bases TGGATTCGGTGCGGATGATGGCCCTGGCCGCCCGCTGGCGCAAAGTGCACGGCGATATCGACTTCGTGATGCTGGCGAAA AACCCGACCATCGACGCCTG
Downstream 100 bases:
>100_bases ATGGCCTGGAAGCGAGAGCTTACGCTGGCGGCGCTGAACGCCAGCAGCGAAAATACCCTGGTGGCGCATCTTGGCATCAT CTACACCCGACTGGAAGAGG
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 261; Mature: 260
Protein sequence:
>261_residues MGAAHPRGAIMAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGESYPFATETLDVADADQVREACSRLL ANTERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGAS KAALKSLALTVGLELAGCGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS SHASHITLQDIVVDGGSTLGA
Sequences:
>Translated_261_residues MGAAHPRGAIMAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGESYPFATETLDVADADQVREACSRLL ANTERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGAS KAALKSLALTVGLELAGCGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS SHASHITLQDIVVDGGSTLGA >Mature_260_residues GAAHPRGAIMAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGESYPFATETLDVADADQVREACSRLLA NTERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASK AALKSLALTVGLELAGCGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASS HASHITLQDIVVDGGSTLGA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=31.2, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=30.078125, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.9595141700405, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=30.6772908366534, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=31.1023622047244, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=31.8725099601594, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4504505, Length=210, Percent_Identity=31.9047619047619, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=24.5283018867925, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723750, Length=155, Percent_Identity=28.3870967741935, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=30.2884615384615, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=26.8199233716475, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=23.4615384615385, Blast_Score=68, Evalue=7e-12, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=89.5161290322581, Blast_Score=450, Evalue=1e-128, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=33.2, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=29.6875, Blast_Score=110, Evalue=8e-26, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=27.34375, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.0395256916996, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=29.6153846153846, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=28.740157480315, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=25.8964143426295, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=30.5555555555556, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=28.7449392712551, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=28.6821705426357, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=32.2834645669291, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=33.7078651685393, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=32.962962962963, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=33.969465648855, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=28.8537549407115, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=31.5985130111524, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=27.5735294117647, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=31.2267657992565, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=31.6793893129771, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=32.9588014981273, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.5660377358491, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=31.7343173431734, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508651, Length=195, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=28.3582089552239, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=28.4615384615385, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=28.4584980237154, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=29.3877551020408, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=28.3400809716599, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=28.8321167883212, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538182, Length=232, Percent_Identity=29.7413793103448, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=28.6885245901639, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=28.4671532846715, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17568967, Length=206, Percent_Identity=30.0970873786408, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.9245283018868, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI193210355, Length=225, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508895, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17564282, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=25.5725190839695, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=266, Percent_Identity=28.1954887218045, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=23.3463035019455, Blast_Score=67, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=26.9035532994924, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=32.421875, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=30.6772908366534, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.156862745098, Blast_Score=98, Evalue=7e-21, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.4347826086957, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=27.3809523809524, Blast_Score=85, Evalue=6e-17, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=31.9230769230769, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=33.1578947368421, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI21356301, Length=205, Percent_Identity=28.2926829268293, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI45554248, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24640117, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI17737361, Length=236, Percent_Identity=29.2372881355932, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 27374; Mature: 27243
Theoretical pI: Translated: 5.04; Mature: 5.04
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGAAHPRGAIMAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGESYPFA CCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCC TETLDVADADQVREACSRLLANTERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGA CCEECCCCHHHHHHHHHHHHCCCHHHEEEEECCCEEEECCCCCCCHHHHHHEEEEECCCH FNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGCGV HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHCEEEECCCE RCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS EEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHCC SHASHITLQDIVVDGGSTLGA CCCCEEEEEEEEEECCCCCCC >Mature Secondary Structure GAAHPRGAIMAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGESYPFA CCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCC TETLDVADADQVREACSRLLANTERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGA CCEECCCCHHHHHHHHHHHHCCCHHHEEEEECCCEEEECCCCCCCHHHHHHEEEEECCCH FNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGCGV HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHCEEEECCCE RCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS EEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHCC SHASHITLQDIVVDGGSTLGA CCCCEEEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]