Click here to switch to the map view.

The map label for this gene is entC [H]

Identifier: 238893643

GI number: 238893643

Start: 1502322

End: 1503509

Strand: Direct

Name: entC [H]

Synonym: KP1_1557

Alternate gene names: 238893643

Gene position: 1502322-1503509 (Clockwise)

Preceding gene: 238893641

Following gene: 238893644

Centisome position: 28.62

GC content: 64.9

Gene sequence:

>1188_bases
TTGGAGGATGATATGGAAACGTCACTGGCTGAGGATGTAAAGAAACCGACCCGGACCCTGTCGCCGGACAGCTTCTTCTT
TATGTCGCCGTACCGCAGTTTTACCACTTCAGGCCGCTTCCGTCGCTTCTCACAGCCCGCCGTTGGCGGCGATGCGCTGG
ACGGCGAGTTCCAGCAGCAGATGGCGGCCGCCTTTGCCGAGGCCCGGACGGCGGGGATCCGCAAGCCGGTGATGGTCGGG
GCTATCCCGTTCGACACCTGTCAGCCTTCCGAGCTCTATATCCCCGAGCGCTGGGAAGCGTTCTCTCGCCCGGAAAAGCA
GCGTTCCGCCCGCTATGCCGCGCCGCTGGAGGCGATGGAGGTGGTGGAGCGTCGGGAGATCCCGGAGCAGGACGCGTTTT
TAGCCATGGTGGAACGCGCCGCCGCGCTGACCGCCACCCCGGAAGTCGACAAAGTGGTGCTATCAAGGCTTATCGATATT
ACCACCCGCGACCGCGTCGACAGCGGCGCGCTGATGGAGCGACTGATCGCCCAGAACCCCGCCAGCTTTAACTTCCACGT
GCCGCTCTCCGACGGCGGCGTGCTGCTGGGCGCCAGCCCGGAGCTGCTGCTGCGTAAAGAAGGACAGCACTTCAGCTCTC
TGCCGCTGGCCGGCTCCGCCCGTCGCCAGCCGGACGATGTGCTGGATCGGGAAGCAGGCAACAGGCTGTTGGCCTCCGGC
AAAGATCGCCACGAGCACGAGCTGGTGACCCAGGCGATGAAGAGCGTGCTGGGCCCGCGCAGCAGTCAGCTGTCGCTACC
GGAGTCGCCGCAGCTGATTACCACCCCGACGCTCTGGCATCTGGCGACGCCGATCGCAGGCACCGCGCTGGCGGAAGAAA
ACGCCATGTCGCTGGCCTGTCTGCTGCACCCGACGCCGGCGCTGAGCGGTTTCCCGCATCAGGCGGCGAAGCGCCTGATT
GCTGAACTGGAACCCTTCGATCGCCAGCTGTTCGGTGGCATCGTCGGCTGGTGCGATGACGAAGGCAACGGCGAGTGGGT
GGTGACTATCCGCTGCGCGCGTCTGCAGCAGCGTACGCTGCGCCTGTTTGCCGGCGCGGGCATTGTTCCGGCCTCCTCGC
CGCTGGGCGAATGGCGCGAAACCGGCGTCAAACTGACCACCATGCTTAACGTATTTGGCTTGAACTAA

Upstream 100 bases:

>100_bases
GGCGGCGCCATGACGTAACGCGGTTGACATGGCGGGCAATACCTTTTAGGTTAGCCAACCAAAATATAAATGATAATTAT
TCTTAATATCTTTATCGTTT

Downstream 100 bases:

>100_bases
GAGGCAAGGATGATTGCATTTACCCGTTGGCCGGAAGAGTTTGCGGCCCGCTATCGTCAAAAAGGCTACTGGCAGGATCT
GCCGTTAACCAATCTGATCA

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MEDDMETSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGRFRRFSQPAVGGDALDGEFQQQMAAAFAEARTAGIRKPVMVG
AIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDI
TTRDRVDSGALMERLIAQNPASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASG
KDRHEHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHPTPALSGFPHQAAKRLI
AELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN

Sequences:

>Translated_395_residues
MEDDMETSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGRFRRFSQPAVGGDALDGEFQQQMAAAFAEARTAGIRKPVMVG
AIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDI
TTRDRVDSGALMERLIAQNPASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASG
KDRHEHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHPTPALSGFPHQAAKRLI
AELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN
>Mature_395_residues
MEDDMETSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGRFRRFSQPAVGGDALDGEFQQQMAAAFAEARTAGIRKPVMVG
AIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDI
TTRDRVDSGALMERLIAQNPASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASG
KDRHEHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHPTPALSGFPHQAAKRLI
AELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=391, Percent_Identity=75.4475703324808, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI87082077, Length=283, Percent_Identity=31.095406360424, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788114, Length=214, Percent_Identity=27.5700934579439, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787518, Length=229, Percent_Identity=28.3842794759825, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 43394; Mature: 43394

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDMETSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGRFRRFSQPAVGGDALDGEFQQQ
CCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCHHHCCCCCCCCCCCCCHHHHHH
MAAAFAEARTAGIRKPVMVGAIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAME
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCHHHHH
VVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRDRVDSGALMERLIAQNP
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
ASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASG
CCEEEEEECCCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCC
KDRHEHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLAC
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHCCHHHHHHHCCCCCEEEE
LLHPTPALSGFPHQAAKRLIAELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTL
EECCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCEEEEEEHHHHHHHHH
RLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN
HHHHCCCCCCCCCCHHHHHHCCEEHHHHHHHHCCC
>Mature Secondary Structure
MEDDMETSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGRFRRFSQPAVGGDALDGEFQQQ
CCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCHHHCCCCCCCCCCCCCHHHHHH
MAAAFAEARTAGIRKPVMVGAIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAME
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCHHHHH
VVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRDRVDSGALMERLIAQNP
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
ASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASG
CCEEEEEECCCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCC
KDRHEHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLAC
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHCCHHHHHHHCCCCCEEEE
LLHPTPALSGFPHQAAKRLIAELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTL
EECCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCEEEEEEHHHHHHHHH
RLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN
HHHHCCCCCCCCCCHHHHHHCCEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]