| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is fabG [H]
Identifier: 238893622
GI number: 238893622
Start: 1477099
End: 1478037
Strand: Reverse
Name: fabG [H]
Synonym: KP1_1536
Alternate gene names: 238893622
Gene position: 1478037-1477099 (Counterclockwise)
Preceding gene: 238893623
Following gene: 238893620
Centisome position: 28.16
GC content: 61.77
Gene sequence:
>939_bases TTGGCGCCACCACGCCGGGACGTCCCCCGGTGGCGCTTCGCTTACCGGGGCTACGTAACACCGCCGAAAGGTTGCCCGGA TAAGGCGCGGCGCGCCGCCATTCGGGAAACAGGGCTCCCGACGTTCGACACTATATTGAAGAGAGTAAACATTATGATCG GTAAAGACTTTGCACAGCAGCTGTTTAACCTGCGGGATCGCGTCGCTTTCGTCACCGGCGCCGGCAGTGGCATCGGCCAG ACCATCGCCTGCAGCCTCGCCAGCGCGGGTGCACGGGTAGTCTGTTTTGATCTTCGCGACGACGGCGGGCTGGCGGAAAC GGTCAGCCATATTGAATCCATCGGCGGTCAGGCTTGTTCTTTTACCGGCGATGTCCGCCAGATTGCCGACCTGCGCGCCG CCGTTGCGCTGGCCAAAAACCGCTTTGGCCGCCTCGACATCGCCGTCAACGCCGCCGGGATCGCCAACGCCAATCCGGCG CTGGAGATGGAGAGCGAGCAATGGCAGCGGGTGATCGATATCAATCTCACCGGCGTATGGAACTCCTGCAAAGCGGAAGC GGAACTGATGCTGGAGTCCGGCGGCGGGTCGATTATCAATATCGCCTCGATGTCGGGGATTATTGTTAACCGCGGCCTCG ACCAGGCGCATTACAACTGCTCCAAAGCCGGCGTGATCCATCTGTCGAAAAGCCTGGCGATGGAGTGGGTGGGCAAAGGG ATCCGCGTCAATTCCATTAGCCCGGGATATACCGCCACGCCGATGAATACCCGTCCGGAGATGGTGCACCAGACCCGCGA GTTTGAAAGCCAGACGCCGATGCAGCGAATGGCGAAGGTGGAAGAGATAGCCGGCCCGGCGCTGTTCCTCGCCAGCGACG CCGCCTCGTTCTGCACCGGCGTAGACCTGGTGGTCGACGGCGGGTTTGTCTGCTGGTGA
Upstream 100 bases:
>100_bases GCTATCTCACCGGGCAGACCATCAATATCGATGGCGGTTTGATTATGTCGTAATCCCCCGCGGGTTAGCGGGCCCCATAG CCCGAATAAGGCGTCCCGCA
Downstream 100 bases:
>100_bases TCCTCTCCTGCTTCAGGGCGCCACGCTGCGGCGCCCCTCTCCACCCCTGCCGTTAACCCAGCGGATACTGTTGAAACGCC GGCAGCGCCTCCCCCTTCTC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 312; Mature: 311
Protein sequence:
>312_residues MAPPRRDVPRWRFAYRGYVTPPKGCPDKARRAAIRETGLPTFDTILKRVNIMIGKDFAQQLFNLRDRVAFVTGAGSGIGQ TIACSLASAGARVVCFDLRDDGGLAETVSHIESIGGQACSFTGDVRQIADLRAAVALAKNRFGRLDIAVNAAGIANANPA LEMESEQWQRVIDINLTGVWNSCKAEAELMLESGGGSIINIASMSGIIVNRGLDQAHYNCSKAGVIHLSKSLAMEWVGKG IRVNSISPGYTATPMNTRPEMVHQTREFESQTPMQRMAKVEEIAGPALFLASDAASFCTGVDLVVDGGFVCW
Sequences:
>Translated_312_residues MAPPRRDVPRWRFAYRGYVTPPKGCPDKARRAAIRETGLPTFDTILKRVNIMIGKDFAQQLFNLRDRVAFVTGAGSGIGQ TIACSLASAGARVVCFDLRDDGGLAETVSHIESIGGQACSFTGDVRQIADLRAAVALAKNRFGRLDIAVNAAGIANANPA LEMESEQWQRVIDINLTGVWNSCKAEAELMLESGGGSIINIASMSGIIVNRGLDQAHYNCSKAGVIHLSKSLAMEWVGKG IRVNSISPGYTATPMNTRPEMVHQTREFESQTPMQRMAKVEEIAGPALFLASDAASFCTGVDLVVDGGFVCW >Mature_311_residues APPRRDVPRWRFAYRGYVTPPKGCPDKARRAAIRETGLPTFDTILKRVNIMIGKDFAQQLFNLRDRVAFVTGAGSGIGQT IACSLASAGARVVCFDLRDDGGLAETVSHIESIGGQACSFTGDVRQIADLRAAVALAKNRFGRLDIAVNAAGIANANPAL EMESEQWQRVIDINLTGVWNSCKAEAELMLESGGGSIINIASMSGIIVNRGLDQAHYNCSKAGVIHLSKSLAMEWVGKGI RVNSISPGYTATPMNTRPEMVHQTREFESQTPMQRMAKVEEIAGPALFLASDAASFCTGVDLVVDGGFVCW
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=36.7424242424242, Blast_Score=130, Evalue=2e-30, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=35.2, Blast_Score=120, Evalue=2e-27, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.5573770491803, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI4758504, Length=226, Percent_Identity=36.7256637168142, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=31.8897637795276, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=35.4978354978355, Blast_Score=103, Evalue=3e-22, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=32.4110671936759, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI66933014, Length=178, Percent_Identity=32.0224719101124, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=31.25, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI83715985, Length=192, Percent_Identity=35.4166666666667, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=35.2631578947368, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=30.9803921568627, Blast_Score=87, Evalue=3e-17, Organism=Homo sapiens, GI31542939, Length=230, Percent_Identity=30, Blast_Score=86, Evalue=6e-17, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.5719844357977, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI4503301, Length=259, Percent_Identity=30.1158301158301, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI109715829, Length=255, Percent_Identity=27.843137254902, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=23.9795918367347, Blast_Score=69, Evalue=8e-12, Organism=Homo sapiens, GI310128830, Length=179, Percent_Identity=25.1396648044693, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI310115468, Length=179, Percent_Identity=25.1396648044693, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI150247226, Length=216, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=26.3959390862944, Blast_Score=66, Evalue=5e-11, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.4568527918782, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=36.3636363636364, Blast_Score=143, Evalue=2e-35, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=37.0967741935484, Blast_Score=143, Evalue=2e-35, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=35.1778656126482, Blast_Score=142, Evalue=2e-35, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=32.1705426356589, Blast_Score=122, Evalue=4e-29, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=33.8582677165354, Blast_Score=120, Evalue=2e-28, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=32.6612903225806, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=32.295719844358, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=32.9365079365079, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.2040816326531, Blast_Score=96, Evalue=4e-21, Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=32.9166666666667, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=29.277566539924, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI2367365, Length=178, Percent_Identity=31.4606741573034, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=29.718875502008, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=30.6010928961749, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=40.5622489959839, Blast_Score=144, Evalue=5e-35, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=36.9477911646586, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=31.6602316602317, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=32.6771653543307, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=31.2820512820513, Blast_Score=99, Evalue=4e-21, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=30.4568527918782, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=29.7619047619048, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.8804780876494, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=31.25, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538182, Length=209, Percent_Identity=34.9282296650718, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=35.2631578947368, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=31.9230769230769, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.1338582677165, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=31.3953488372093, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=30.5019305019305, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=29.2307692307692, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=26.4925373134328, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=27.2373540856031, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17567345, Length=214, Percent_Identity=28.0373831775701, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=28.2945736434109, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.7992277992278, Blast_Score=77, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=29.7709923664122, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.9693486590038, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17508895, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=25, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=25.390625, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=30.1526717557252, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=27.4809160305344, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17507613, Length=283, Percent_Identity=26.5017667844523, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI32563809, Length=283, Percent_Identity=26.8551236749117, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=27.6381909547739, Blast_Score=65, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=3e-21, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=30.46875, Blast_Score=85, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6320089, Length=217, Percent_Identity=27.6497695852535, Blast_Score=63, Evalue=7e-11, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=33.984375, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=36.4, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=33.201581027668, Blast_Score=119, Evalue=3e-27, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=35.1778656126482, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI17737361, Length=236, Percent_Identity=34.3220338983051, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI21355319, Length=278, Percent_Identity=29.4964028776978, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=29.5019157088123, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=34.2105263157895, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24644337, Length=216, Percent_Identity=30.0925925925926, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI281364892, Length=200, Percent_Identity=29, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24665243, Length=238, Percent_Identity=29.8319327731092, Blast_Score=76, Evalue=4e-14, Organism=Drosophila melanogaster, GI221331218, Length=233, Percent_Identity=30.0429184549356, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24665247, Length=239, Percent_Identity=29.7071129707113, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331216, Length=234, Percent_Identity=29.9145299145299, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI24640492, Length=156, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007234, Length=197, Percent_Identity=35.0253807106599, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI21357673, Length=217, Percent_Identity=26.7281105990783, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 33565; Mature: 33434
Theoretical pI: Translated: 7.99; Mature: 7.99
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.6 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 5.8 %Cys+Met (Translated Protein) 2.6 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAPPRRDVPRWRFAYRGYVTPPKGCPDKARRAAIRETGLPTFDTILKRVNIMIGKDFAQQ CCCCCCCCCCHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH LFNLRDRVAFVTGAGSGIGQTIACSLASAGARVVCFDLRDDGGLAETVSHIESIGGQACS HHHHHHHEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEE FTGDVRQIADLRAAVALAKNRFGRLDIAVNAAGIANANPALEMESEQWQRVIDINLTGVW CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEECHHHCCEEEEEEEECCC NSCKAEAELMLESGGGSIINIASMSGIIVNRGLDQAHYNCSKAGVIHLSKSLAMEWVGKG CCCCCCEEEEEECCCCCEEEEECCCCEEEECCCCHHHCCCCCCCEEEHHHHHHHHHHCCC IRVNSISPGYTATPMNTRPEMVHQTREFESQTPMQRMAKVEEIAGPALFLASDAASFCTG EEEECCCCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCHHHHHCC VDLVVDGGFVCW CEEEECCCEECC >Mature Secondary Structure APPRRDVPRWRFAYRGYVTPPKGCPDKARRAAIRETGLPTFDTILKRVNIMIGKDFAQQ CCCCCCCCCHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH LFNLRDRVAFVTGAGSGIGQTIACSLASAGARVVCFDLRDDGGLAETVSHIESIGGQACS HHHHHHHEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEE FTGDVRQIADLRAAVALAKNRFGRLDIAVNAAGIANANPALEMESEQWQRVIDINLTGVW CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEECHHHCCEEEEEEEECCC NSCKAEAELMLESGGGSIINIASMSGIIVNRGLDQAHYNCSKAGVIHLSKSLAMEWVGKG CCCCCCEEEEEECCCCCEEEEECCCCEEEECCCCHHHCCCCCCCEEEHHHHHHHHHHCCC IRVNSISPGYTATPMNTRPEMVHQTREFESQTPMQRMAKVEEIAGPALFLASDAASFCTG EEEECCCCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCHHHHHCC VDLVVDGGFVCW CEEEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]