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The map label for this gene is ylbC [H]

Identifier: 238893478

GI number: 238893478

Start: 1325586

End: 1326635

Strand: Reverse

Name: ylbC [H]

Synonym: KP1_1373

Alternate gene names: 238893478

Gene position: 1326635-1325586 (Counterclockwise)

Preceding gene: 238893483

Following gene: 238893477

Centisome position: 25.28

GC content: 52.86

Gene sequence:

>1050_bases
ATGAAAGTCAGTCGGGAAACACTTCATCAGCTTATTGCTAATAAGCTGAACGCAGCAGGACTCACTCATAATCACGCGGA
TATTATTGCCGATGTGTTGGTTTATGCCGATGCCAGAGGCATTCATTCGCACGGCGCGGTTCGTGTTGAATATTATGCTG
AACGAATTTCAAAAGGCGGCACCAATCGTCATCCCACCTTTAGCTTTGAAAAAACCGGTCCCTGCAGCGGCATTTTGCAT
GCCGATAACGCCGCCGGCCAGGTCGCCGCCAAAATGGGCATGGAACATGCCATTGAGATCGCCCGGCAAAATGGCATAGC
CGTAGTGGGTATCCGGCGCATGGGACACAGCGGGGCCATCTCGTACTTCACGCAGCAGGCGGCTCGCGCCGGGCTGATTG
GCCTCTCGCTGTGTCAGTCAGACCCGATGGTCGTCCCTTTTGGCGGAGCGGAGATCTACTACGGCACCAACCCGCTGGCC
TTCGCCGCTCCCGGCGAGGGCGACGATATCATCACCTTCGATATGGCCACCACCGTCCAGGCGTGGGGAAAGATCCTTGA
TGCTCGTTCTCGCCATGAAAGCATTCCCGATAGCTGGGCGGTGGACAAAAACGGCGCCCCAACCACGGATCCTTTTGCCG
TCCATGCTCTGCTTCCTGCCGCCGGTCCCAAAGGTTACGGGCTGATGATGATGATTGACGTCCTATCCGGCATTTTGCTC
AACCTTCCGTTTGGTCGCCAGGTCAGCTCGATGTACGACAACCTTAGCCAGGGACGTGAGTTAGGACAATTGCATATAGT
GATTAATCCTGACTTTTTCTCCTCCAGCGCTTTATTTCGCCAGCACATTAGCGACACCATGCGCGAATTAAGCGCCATTA
CGCCAGCACCTGGATTTAGTCAGGTTTATTACCCGGGGCAGAATCTGGATATCAATGAGAAAAACAGCGCTGTCAACGGG
ATCGAAATCGTTGATGAGATTTATGACTATCTGGTTTCAGACGCTTTATATAACCGCTCTTATGAAACCAATTCCCCTTT
TGCTCAATAA

Upstream 100 bases:

>100_bases
CTAACACTGGTCATTTAACTATACAGATCACAATTTCAGTTTCTTTTCCCCGTATTTTAGTCAGCAGTCAGGCTCTACAC
CGTCGTTAAAAGGAAGACAG

Downstream 100 bases:

>100_bases
AATAAGTAACAGGAGTTATGTATGACTCATTCTTTTCGACAGGCAATTGAAGAGACATTGCCCTGGCTTTCCTCTTTCGG
CGCCGACCCTACCGGCGGAC

Product: putative malate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKVSRETLHQLIANKLNAAGLTHNHADIIADVLVYADARGIHSHGAVRVEYYAERISKGGTNRHPTFSFEKTGPCSGILH
ADNAAGQVAAKMGMEHAIEIARQNGIAVVGIRRMGHSGAISYFTQQAARAGLIGLSLCQSDPMVVPFGGAEIYYGTNPLA
FAAPGEGDDIITFDMATTVQAWGKILDARSRHESIPDSWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGILL
NLPFGRQVSSMYDNLSQGRELGQLHIVINPDFFSSSALFRQHISDTMRELSAITPAPGFSQVYYPGQNLDINEKNSAVNG
IEIVDEIYDYLVSDALYNRSYETNSPFAQ

Sequences:

>Translated_349_residues
MKVSRETLHQLIANKLNAAGLTHNHADIIADVLVYADARGIHSHGAVRVEYYAERISKGGTNRHPTFSFEKTGPCSGILH
ADNAAGQVAAKMGMEHAIEIARQNGIAVVGIRRMGHSGAISYFTQQAARAGLIGLSLCQSDPMVVPFGGAEIYYGTNPLA
FAAPGEGDDIITFDMATTVQAWGKILDARSRHESIPDSWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGILL
NLPFGRQVSSMYDNLSQGRELGQLHIVINPDFFSSSALFRQHISDTMRELSAITPAPGFSQVYYPGQNLDINEKNSAVNG
IEIVDEIYDYLVSDALYNRSYETNSPFAQ
>Mature_349_residues
MKVSRETLHQLIANKLNAAGLTHNHADIIADVLVYADARGIHSHGAVRVEYYAERISKGGTNRHPTFSFEKTGPCSGILH
ADNAAGQVAAKMGMEHAIEIARQNGIAVVGIRRMGHSGAISYFTQQAARAGLIGLSLCQSDPMVVPFGGAEIYYGTNPLA
FAAPGEGDDIITFDMATTVQAWGKILDARSRHESIPDSWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGILL
NLPFGRQVSSMYDNLSQGRELGQLHIVINPDFFSSSALFRQHISDTMRELSAITPAPGFSQVYYPGQNLDINEKNSAVNG
IEIVDEIYDYLVSDALYNRSYETNSPFAQ

Specific function: Involved in the anaerobic utilization of allantoin [H]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=349, Percent_Identity=83.0945558739255, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1787020, Length=321, Percent_Identity=29.2834890965732, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790000, Length=333, Percent_Identity=24.3243243243243, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17507179, Length=305, Percent_Identity=33.4426229508197, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17536633, Length=312, Percent_Identity=31.4102564102564, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45553211, Length=297, Percent_Identity=30.6397306397306, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24667912, Length=297, Percent_Identity=30.6397306397306, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24667908, Length=297, Percent_Identity=30.6397306397306, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24667904, Length=297, Percent_Identity=30.6397306397306, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24658010, Length=302, Percent_Identity=27.4834437086093, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24648360, Length=307, Percent_Identity=25.7328990228013, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767
- InterPro:   IPR017590 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: =1.1.1.154 [H]

Molecular weight: Translated: 37726; Mature: 37726

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSRETLHQLIANKLNAAGLTHNHADIIADVLVYADARGIHSHGAVRVEYYAERISKGG
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCCC
TNRHPTFSFEKTGPCSGILHADNAAGQVAAKMGMEHAIEIARQNGIAVVGIRRMGHSGAI
CCCCCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHH
SYFTQQAARAGLIGLSLCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDDIITFDMATTVQ
HHHHHHHHHHCHHHHHHHCCCCEEEEECCEEEEECCCCEEEECCCCCCCEEEEEHHHHHH
AWGKILDARSRHESIPDSWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGILL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH
NLPFGRQVSSMYDNLSQGRELGQLHIVINPDFFSSSALFRQHISDTMRELSAITPAPGFS
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
QVYYPGQNLDINEKNSAVNGIEIVDEIYDYLVSDALYNRSYETNSPFAQ
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVSRETLHQLIANKLNAAGLTHNHADIIADVLVYADARGIHSHGAVRVEYYAERISKGG
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCCC
TNRHPTFSFEKTGPCSGILHADNAAGQVAAKMGMEHAIEIARQNGIAVVGIRRMGHSGAI
CCCCCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHH
SYFTQQAARAGLIGLSLCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDDIITFDMATTVQ
HHHHHHHHHHCHHHHHHHCCCCEEEEECCEEEEECCCCEEEECCCCCCCEEEEEHHHHHH
AWGKILDARSRHESIPDSWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGILL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH
NLPFGRQVSSMYDNLSQGRELGQLHIVINPDFFSSSALFRQHISDTMRELSAITPAPGFS
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
QVYYPGQNLDINEKNSAVNGIEIVDEIYDYLVSDALYNRSYETNSPFAQ
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]