BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is ybbO [H]

Identifier: 238893459

GI number: 238893459

Start: 1303053

End: 1303862

Strand: Reverse

Name: ybbO [H]

Synonym: KP1_1350

Alternate gene names: 238893459

Gene position: 1303862-1303053 (Counterclockwise)

Preceding gene: 238893460

Following gene: 238893458

Centisome position: 24.84

GC content: 60.49

Gene sequence:

>810_bases
ATGACTCCTGAACGCCAGGGGTCGCTGACAGGTAAAGTTATGCAAAAAACGGTTTTAGTGACAGGCTGTTCCAGCGGAAT
TGGTCTGGAAAGCGCGCTGGATTTAACCCGCCAGGGCTTTCGCGTGCTGGCGGCCTGCCGCAAAGCAGAGGATGTCGCGC
GGATGCAGGAGCTGGGGCTAACCGGTATTTTGCTCGATCTGGATGACCCGCAGAGCGTGGAGCGCGCGGCAGCGGAGGTG
ATTGCGCTGACCGATAATCGTCTCTACGGCCTGTTCAATAACGCCGGGTATGGCGTCTATGGCCCGCTGAACACCATCAG
CCGCCAGCAGATGGAACAGCAATTTTCCGCTAACTTTTTCGGCGCGCATCAGCTCACCATGCTGCTGCTGCCGGCGATGA
CGCCGCACGGCGAAGGACGCATCGTGATGACCTCCTCGGTGATGGGGCTTATCGCCAGTCCCGGCCGCGGAGCCTATGCC
GCCAGTAAATATGCCCTCGAGGCGTGGTCCGACGCGCTGCGCATGGAGCTGCGCCACAGCGGTATTCAGGTCAGCCTGAT
TGAACCGGGCCCGATCCGCACCCGCTTTACCGATAACGTCAACCAGACGCAAAGCGATAAGCCCGTAGAAAATCCGGGCA
TCGCCGCCCGCTTTACCCTCGGGCCGGAGGCGGTGGTGGAAAAAGTGCGCCATGCTTTTACCAGCGATAAACCAAAGCTG
CGCTATCCGGTCACCCTGGTCACCCACGCGGTGGCGCTGCTTAAGCGCCTGCTGCCTGCCCGCGCGATGGACAAAATTAT
CCACGGCTGA

Upstream 100 bases:

>100_bases
AAGCCGCAATGGATGCAGGACGACGGCATTCATCCAAATCGCGACGCGCAGCCGTTTATCGCCGACTGGATGGCGAAGCG
GCTGGCTCCCTTAGTTAATC

Downstream 100 bases:

>100_bases
GTTGAAGCGCGGAATGCCGCCCCCATGTAAAACAGAAATCGACTAACGAGAAATGCCCATGTCCGAACAGAATATTGTCA
ACATTAGCGAAGCGAACCTG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGLTGILLDLDDPQSVERAAAEV
IALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYA
ASKYALEAWSDALRMELRHSGIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL
RYPVTLVTHAVALLKRLLPARAMDKIIHG

Sequences:

>Translated_269_residues
MTPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGLTGILLDLDDPQSVERAAAEV
IALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYA
ASKYALEAWSDALRMELRHSGIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL
RYPVTLVTHAVALLKRLLPARAMDKIIHG
>Mature_268_residues
TPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGLTGILLDLDDPQSVERAAAEVI
ALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYAA
SKYALEAWSDALRMELRHSGIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKLR
YPVTLVTHAVALLKRLLPARAMDKIIHG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI50726952, Length=186, Percent_Identity=42.4731182795699, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7657478, Length=251, Percent_Identity=34.2629482071713, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI40548397, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI214010158, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI214010156, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI22758144, Length=271, Percent_Identity=31.7343173431734, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI22507405, Length=257, Percent_Identity=31.1284046692607, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI150247226, Length=291, Percent_Identity=30.5841924398625, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI223718074, Length=259, Percent_Identity=32.8185328185328, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI19743808, Length=292, Percent_Identity=30.4794520547945, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI44680136, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI44680133, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI17738292, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI119392083, Length=207, Percent_Identity=35.7487922705314, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=31.8840579710145, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=31.4720812182741, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI142976729, Length=271, Percent_Identity=27.3062730627306, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4504503, Length=206, Percent_Identity=30.5825242718447, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32455239, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI5031765, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786701, Length=269, Percent_Identity=82.5278810408922, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI87082100, Length=205, Percent_Identity=33.1707317073171, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=211, Percent_Identity=31.2796208530806, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=29.6875, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367365, Length=191, Percent_Identity=31.413612565445, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786812, Length=207, Percent_Identity=28.0193236714976, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787820, Length=219, Percent_Identity=29.6803652968037, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788459, Length=211, Percent_Identity=29.8578199052133, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787526, Length=206, Percent_Identity=31.0679611650485, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=286, Percent_Identity=28.3216783216783, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193210355, Length=282, Percent_Identity=30.1418439716312, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17557780, Length=265, Percent_Identity=27.1698113207547, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71997402, Length=192, Percent_Identity=32.2916666666667, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=198, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32563809, Length=288, Percent_Identity=25.3472222222222, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17507613, Length=288, Percent_Identity=25.3472222222222, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563807, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=225, Percent_Identity=27.5555555555556, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=193, Percent_Identity=30.5699481865285, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=36.5979381443299, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24651139, Length=243, Percent_Identity=31.6872427983539, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356301, Length=214, Percent_Identity=30.3738317757009, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=31.7204301075269, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45554248, Length=200, Percent_Identity=34.5, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640117, Length=200, Percent_Identity=34.5, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=30.8080808080808, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=29.8969072164948, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45553409, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647948, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647946, Length=209, Percent_Identity=29.6650717703349, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=197, Percent_Identity=27.9187817258883, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29228; Mature: 29097

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGL
CCCCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGILLDLDDPQSVERAAAEVIALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFF
EEEEEECCCCHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC
GAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYAASKYALEAWSDALRMELRHS
CHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL
CEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCE
RYPVTLVTHAVALLKRLLPARAMDKIIHG
ECHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPERQGSLTGKVMQKTVLVTGCSSGIGLESALDLTRQGFRVLAACRKAEDVARMQELGL
CCCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGILLDLDDPQSVERAAAEVIALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFF
EEEEEECCCCHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC
GAHQLTMLLLPAMTPHGEGRIVMTSSVMGLIASPGRGAYAASKYALEAWSDALRMELRHS
CHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GIQVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVEKVRHAFTSDKPKL
CEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCE
RYPVTLVTHAVALLKRLLPARAMDKIIHG
ECHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]