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The map label for this gene is gatC [H]

Identifier: 238893239

GI number: 238893239

Start: 1081325

End: 1082587

Strand: Reverse

Name: gatC [H]

Synonym: KP1_1108

Alternate gene names: 238893239

Gene position: 1082587-1081325 (Counterclockwise)

Preceding gene: 238893240

Following gene: 238893238

Centisome position: 20.63

GC content: 49.72

Gene sequence:

>1263_bases
ATGGATATTATCAACAGCATTATTAGTCTGGGGGCATCAGTAATGATGCCAGTAATATTCTTTATTATCGCGCTTTGCTT
TGGCGTTAAAATCGGTACGGCATTTAAAGCAGGGATGCTGGTAGGCATTGGTTTTGAAGGGGTGGGGCTGGTGATTGGCC
TGCTGCTGACAAACCTGGGCCCGGCATCGCAGGCGATGGTTGAGCGTATCGGCCTGCAGTTAACGGTCGTTGATACCGGT
TGGCCTACCGCATCGACCATTGGTTGGGGTTCGCCGCTGATGCTGCCCGTCGTGGTGGGCTTTATCGTCATCAACCTGGC
CATGCTTCTGTTGAAATTAACCAAAACGGTGAATATCGATATTTTTAACTACTGGATTTTCCTGATCATGGGGTCTGTGG
TCTATGCCGGAACGGGAAATTACTGGCTTTCGGTCGGTATTACATTCGCTATTTTTGTGTTGACGCTATTGGCGGCAGAT
TTAACGGCGCCGTATTTACAAAAAAACTATAATCTTAAAGGGATATCATTCCCCCATCTTACCTGTATAGCTTACGTGCC
GTTTGGCATTGCCTGTAATTACATCATTGATAAGATCCCGCTTATCAATAAAATCAATTTCGACCCGGAAAGTATTAATA
AAAAATTCGGCGTTTTTGGCGAGCCTGTTACCCTGGGGTTTGTGCTGGGACTGCTGTTGGCCTTCCTGGCTGGATATGAC
GTTTCCGCGGCCGTTTCACTGGCCATTAAGGTTTCAGCCGCCATGCTGCTGCTGCCTAAAATGATTGAAATTCTGGTGCA
GGGATTGTTGATTGTCCGTGATGCCGCTGAAGCAAAACTGAAGGCTAAATTCCCGGGGCGCGATTTTTACATCGGGATGG
ATACGGCGTTACTGATCGGTGAACCTTCGGTACTGGCGACCGGTCTGCTGTTAATCCCTATGGCTGTGGTGCTGTCTATC
ATTCTGCCCGGCAACCGCGTACTGCCCTTTGTCGATCTGGCTTCATTAATGTTCCTGCTGGCAATGGTCACGCCGTTCTG
TAAACGAAATATGTTCCGCATGTTCATAACCGGAACCCTGATCGTGACCTGCATCCTGTATGTCGGGACGGACATTTCGC
AAGAATACACTCAGGCGGCGGTGAACTCGCATATTCCGGTGCCGGAAGGGATGGCCGAGATCACCAATATCGTCGGCGGC
GCCACGACGCCTGTCGGCTGGCTCGCCGTCAAATTTGGCGAGTTTTTTAGCGCCACACCTTAG

Upstream 100 bases:

>100_bases
AAACTCAGTTAAATATTAAAAGAACCATTAAAGGTATTAACAGGGCCCAATGGGCACGGGTTTACTCGTGCCCAATTCGC
CCGCCTTTTAAGGAATCATT

Downstream 100 bases:

>100_bases
TACAAGGCCACTCAAGTAAACAGAGGGCAAACTGTTGCCCTCTGTTTCTTCCTCTTATTCTGTGCGCTGAATAGCTGGCT
CAGCTACGCCCCTGGTTTGA

Product: hypothetical protein

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDIINSIISLGASVMMPVIFFIIALCFGVKIGTAFKAGMLVGIGFEGVGLVIGLLLTNLGPASQAMVERIGLQLTVVDTG
WPTASTIGWGSPLMLPVVVGFIVINLAMLLLKLTKTVNIDIFNYWIFLIMGSVVYAGTGNYWLSVGITFAIFVLTLLAAD
LTAPYLQKNYNLKGISFPHLTCIAYVPFGIACNYIIDKIPLINKINFDPESINKKFGVFGEPVTLGFVLGLLLAFLAGYD
VSAAVSLAIKVSAAMLLLPKMIEILVQGLLIVRDAAEAKLKAKFPGRDFYIGMDTALLIGEPSVLATGLLLIPMAVVLSI
ILPGNRVLPFVDLASLMFLLAMVTPFCKRNMFRMFITGTLIVTCILYVGTDISQEYTQAAVNSHIPVPEGMAEITNIVGG
ATTPVGWLAVKFGEFFSATP

Sequences:

>Translated_420_residues
MDIINSIISLGASVMMPVIFFIIALCFGVKIGTAFKAGMLVGIGFEGVGLVIGLLLTNLGPASQAMVERIGLQLTVVDTG
WPTASTIGWGSPLMLPVVVGFIVINLAMLLLKLTKTVNIDIFNYWIFLIMGSVVYAGTGNYWLSVGITFAIFVLTLLAAD
LTAPYLQKNYNLKGISFPHLTCIAYVPFGIACNYIIDKIPLINKINFDPESINKKFGVFGEPVTLGFVLGLLLAFLAGYD
VSAAVSLAIKVSAAMLLLPKMIEILVQGLLIVRDAAEAKLKAKFPGRDFYIGMDTALLIGEPSVLATGLLLIPMAVVLSI
ILPGNRVLPFVDLASLMFLLAMVTPFCKRNMFRMFITGTLIVTCILYVGTDISQEYTQAAVNSHIPVPEGMAEITNIVGG
ATTPVGWLAVKFGEFFSATP
>Mature_420_residues
MDIINSIISLGASVMMPVIFFIIALCFGVKIGTAFKAGMLVGIGFEGVGLVIGLLLTNLGPASQAMVERIGLQLTVVDTG
WPTASTIGWGSPLMLPVVVGFIVINLAMLLLKLTKTVNIDIFNYWIFLIMGSVVYAGTGNYWLSVGITFAIFVLTLLAAD
LTAPYLQKNYNLKGISFPHLTCIAYVPFGIACNYIIDKIPLINKINFDPESINKKFGVFGEPVTLGFVLGLLLAFLAGYD
VSAAVSLAIKVSAAMLLLPKMIEILVQGLLIVRDAAEAKLKAKFPGRDFYIGMDTALLIGEPSVLATGLLLIPMAVVLSI
ILPGNRVLPFVDLASLMFLLAMVTPFCKRNMFRMFITGTLIVTCILYVGTDISQEYTQAAVNSHIPVPEGMAEITNIVGG
ATTPVGWLAVKFGEFFSATP

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=412, Percent_Identity=39.3203883495146, Blast_Score=314, Evalue=9e-87,
Organism=Escherichia coli, GI1790758, Length=391, Percent_Identity=38.1074168797954, Blast_Score=250, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 45033; Mature: 45033

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIINSIISLGASVMMPVIFFIIALCFGVKIGTAFKAGMLVGIGFEGVGLVIGLLLTNLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCEEEEECCCHHHHHHHHHHHCCC
PASQAMVERIGLQLTVVDTGWPTASTIGWGSPLMLPVVVGFIVINLAMLLLKLTKTVNID
CHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IFNYWIFLIMGSVVYAGTGNYWLSVGITFAIFVLTLLAADLTAPYLQKNYNLKGISFPHL
HHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHH
TCIAYVPFGIACNYIIDKIPLINKINFDPESINKKFGVFGEPVTLGFVLGLLLAFLAGYD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VSAAVSLAIKVSAAMLLLPKMIEILVQGLLIVRDAAEAKLKAKFPGRDFYIGMDTALLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCEEEEC
EPSVLATGLLLIPMAVVLSIILPGNRVLPFVDLASLMFLLAMVTPFCKRNMFRMFITGTL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVTCILYVGTDISQEYTQAAVNSHIPVPEGMAEITNIVGGATTPVGWLAVKFGEFFSATP
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIINSIISLGASVMMPVIFFIIALCFGVKIGTAFKAGMLVGIGFEGVGLVIGLLLTNLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCEEEEECCCHHHHHHHHHHHCCC
PASQAMVERIGLQLTVVDTGWPTASTIGWGSPLMLPVVVGFIVINLAMLLLKLTKTVNID
CHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IFNYWIFLIMGSVVYAGTGNYWLSVGITFAIFVLTLLAADLTAPYLQKNYNLKGISFPHL
HHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHH
TCIAYVPFGIACNYIIDKIPLINKINFDPESINKKFGVFGEPVTLGFVLGLLLAFLAGYD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VSAAVSLAIKVSAAMLLLPKMIEILVQGLLIVRDAAEAKLKAKFPGRDFYIGMDTALLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCEEEEC
EPSVLATGLLLIPMAVVLSIILPGNRVLPFVDLASLMFLLAMVTPFCKRNMFRMFITGTL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVTCILYVGTDISQEYTQAAVNSHIPVPEGMAEITNIVGGATTPVGWLAVKFGEFFSATP
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]