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The map label for this gene is yybE [H]

Identifier: 238893048

GI number: 238893048

Start: 869628

End: 870524

Strand: Direct

Name: yybE [H]

Synonym: KP1_0886

Alternate gene names: 238893048

Gene position: 869628-870524 (Clockwise)

Preceding gene: 238893046

Following gene: 238893057

Centisome position: 16.57

GC content: 47.6

Gene sequence:

>897_bases
ATGAACCTAAAGCAACTTTATTATTTTAAACGTCTGTCTGAAACTGAGCATTACACCGAAGCCGCCTCCAGTCTGTGCAT
CACCCAGCCCTCGCTAAGCCACGCGATATCGGAGCTGGAGAAGGAGTTAGGGGTCGCGCTATTCGCCAGACAGGGGCGGA
ACGTAAAAATTACCCAAAACGGCAAGCGTTTTTTGCCGTATGTTGAAGATGCGCTGGCCTCGCTGGAGAACGGACGCATG
ATATTGCAAAAAAATGGCGCTGAGAATAAAGAGAATATTCGCATCGCCTTTATTTACACGATGGGGGAGTATGTTGTTCC
ACAGTTAATTAATAAATATTCTCTTTCACCTGAATGTCACAATGTGACTTTTTCTTTTACTCAAGGGACATCGCTGACGC
TGTTGCAGGAGCTGAAGGCCGGAAAAGTCGATCTGGCGATCTGCTCTTATATTGCCGATGAACCCGATATCGATTTTATT
CCGGTGATCCAGCAGGAACTGGTGGTGGTCACGGCAAAGGATCATCCGCTGGCCCGGCTATATGAACATGAAGTCGATCT
GGTGGAGACGATTCATTATCCGTATATCTATTTTTCAGAAAATAGCGGCTTACGTCCGTTTATCGATAATGTATTTATGC
AGCAAAAGCTGGTGCCGGAGATCGCCTGCTATGTGGATGAGGATACGGCGATGGCCGGGCTGGTGAGTATTGACTACGGG
ATCGCGATTATGCCGCGCATTACCGCGCTCTCCTATTACAACGTCCATATCCTGAAGATTAAAAACACCATCCCCCCCCG
CTATATCTATCTGGCGACCATGAAAGACAAGGGGCTCTCTCCGGCGCTGGAGTCATTTAAAAATGTGGTTATCCACGACA
GCCAGAAGATCTGTTAA

Upstream 100 bases:

>100_bases
TGATGTAACGCCGATATTTACCCGTTCATGCGCATTATTGGTGGCTTGCATGGTATATTAGCGTCAGTGCATTTATTCTT
ATATTATACGGGTAAAAATA

Downstream 100 bases:

>100_bases
CGGATGGCCCGGATGTGACCTCCGGGCCATCCGGATATCAGGAGAGAATATCCATCACTTCACGCAGCTTAGCGATGGCG
ATCTGCCCAGGCGCGGAGGC

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNLKQLYYFKRLSETEHYTEAASSLCITQPSLSHAISELEKELGVALFARQGRNVKITQNGKRFLPYVEDALASLENGRM
ILQKNGAENKENIRIAFIYTMGEYVVPQLINKYSLSPECHNVTFSFTQGTSLTLLQELKAGKVDLAICSYIADEPDIDFI
PVIQQELVVVTAKDHPLARLYEHEVDLVETIHYPYIYFSENSGLRPFIDNVFMQQKLVPEIACYVDEDTAMAGLVSIDYG
IAIMPRITALSYYNVHILKIKNTIPPRYIYLATMKDKGLSPALESFKNVVIHDSQKIC

Sequences:

>Translated_298_residues
MNLKQLYYFKRLSETEHYTEAASSLCITQPSLSHAISELEKELGVALFARQGRNVKITQNGKRFLPYVEDALASLENGRM
ILQKNGAENKENIRIAFIYTMGEYVVPQLINKYSLSPECHNVTFSFTQGTSLTLLQELKAGKVDLAICSYIADEPDIDFI
PVIQQELVVVTAKDHPLARLYEHEVDLVETIHYPYIYFSENSGLRPFIDNVFMQQKLVPEIACYVDEDTAMAGLVSIDYG
IAIMPRITALSYYNVHILKIKNTIPPRYIYLATMKDKGLSPALESFKNVVIHDSQKIC
>Mature_298_residues
MNLKQLYYFKRLSETEHYTEAASSLCITQPSLSHAISELEKELGVALFARQGRNVKITQNGKRFLPYVEDALASLENGRM
ILQKNGAENKENIRIAFIYTMGEYVVPQLINKYSLSPECHNVTFSFTQGTSLTLLQELKAGKVDLAICSYIADEPDIDFI
PVIQQELVVVTAKDHPLARLYEHEVDLVETIHYPYIYFSENSGLRPFIDNVFMQQKLVPEIACYVDEDTAMAGLVSIDYG
IAIMPRITALSYYNVHILKIKNTIPPRYIYLATMKDKGLSPALESFKNVVIHDSQKIC

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=25.938566552901, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788887, Length=301, Percent_Identity=27.2425249169435, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI157672245, Length=290, Percent_Identity=24.1379310344828, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=27.0916334661355, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=26.2096774193548, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788481, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790399, Length=183, Percent_Identity=28.9617486338798, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=25.4032258064516, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790208, Length=296, Percent_Identity=22.2972972972973, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=21.8623481781377, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788748, Length=300, Percent_Identity=24.3333333333333, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790262, Length=300, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081904, Length=242, Percent_Identity=21.900826446281, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=159, Percent_Identity=27.0440251572327, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790783, Length=249, Percent_Identity=23.6947791164659, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=293, Percent_Identity=20.1365187713311, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=21.4285714285714, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=20.8, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33828; Mature: 33828

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQLYYFKRLSETEHYTEAASSLCITQPSLSHAISELEKELGVALFARQGRNVKITQN
CCHHHHHHHHHHCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCEEEECCCCEEEEECC
GKRFLPYVEDALASLENGRMILQKNGAENKENIRIAFIYTMGEYVVPQLINKYSLSPECH
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCC
NVTFSFTQGTSLTLLQELKAGKVDLAICSYIADEPDIDFIPVIQQELVVVTAKDHPLARL
EEEEEEECCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCHHHH
YEHEVDLVETIHYPYIYFSENSGLRPFIDNVFMQQKLVPEIACYVDEDTAMAGLVSIDYG
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHEEEEEECCC
IAIMPRITALSYYNVHILKIKNTIPPRYIYLATMKDKGLSPALESFKNVVIHDSQKIC
EEEECHHEEEEEEEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHEEEECCCCCC
>Mature Secondary Structure
MNLKQLYYFKRLSETEHYTEAASSLCITQPSLSHAISELEKELGVALFARQGRNVKITQN
CCHHHHHHHHHHCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCEEEECCCCEEEEECC
GKRFLPYVEDALASLENGRMILQKNGAENKENIRIAFIYTMGEYVVPQLINKYSLSPECH
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCC
NVTFSFTQGTSLTLLQELKAGKVDLAICSYIADEPDIDFIPVIQQELVVVTAKDHPLARL
EEEEEEECCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCHHHH
YEHEVDLVETIHYPYIYFSENSGLRPFIDNVFMQQKLVPEIACYVDEDTAMAGLVSIDYG
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHEEEEEECCC
IAIMPRITALSYYNVHILKIKNTIPPRYIYLATMKDKGLSPALESFKNVVIHDSQKIC
EEEECHHEEEEEEEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]