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The map label for this gene is nhaR [H]

Identifier: 238893004

GI number: 238893004

Start: 815736

End: 816632

Strand: Direct

Name: nhaR [H]

Synonym: KP1_0838

Alternate gene names: 238893004

Gene position: 815736-816632 (Clockwise)

Preceding gene: 238893003

Following gene: 238893006

Centisome position: 15.54

GC content: 56.63

Gene sequence:

>897_bases
ATGTCACATATTAACTACAATCATCTGTACTACTTCTGGCACGTGTATAAAGAAGGGTCCGTCGTGGGCGCGGCGGAGGC
GCTGTTTCTGACGCCGCAGACCATTACCGGGCAGATCAAAGCCCTGGAGGAGCGCCTGCAGGGGAAATTATTTAAGCGAA
AGGGAAGGGGGCTTGAGCCGAGCGAGCTGGGGGAGCTGGTTTTTCGCTATGCCGACCGGATGTTTACCCTCAGCCAGGAG
ATGCTCGACATCGTCAACTATCGCAAAGAGTCGAACCTGCTGTTTGACGTCGGCGTGGCCGATGCGCTCTCGAAACGGCT
GGTCAGCGGCGTGCTGGATGCCGCCGTCGTTGAGAGCGAGCAGATTCATCTGCGCTGTTTTGAATCCACTCATGAGCTGC
TGCTGGAGCAGCTGAGCCAGCATAAGCTCGACATGATTATCTCTGACTGCCCGATCGACTCGACGCAGCAGGAAGGGCTA
TTTTCGGTGAAGATCGGCGAGTGCAGCGTCAGCTTCTGGTGCATGAATCCGGCGCCGACGAAGCCGTTCCCGGCCTGCCT
CGAAGAGCGGCGGCTGCTGATCCCCGGCCGGCGATCGATGCTGGGACGTAAGCTGCTGAACTGGATTAACGTGCAGGGCC
TGAAGGTGGAGATCCTCGGCGAGTTTGACGACGCGGCGCTCATGAAAGCCTTCGGCGCCGCACATAATGCGATATTTGTC
GCGCCGACGCTCTACGCGCATGATTTCTACCATGATGAATCGATTGTCGAAATTGGCCGTATGGATAGCGTGATGGAGGA
GTATCACGCTATTTTCGCTGAACGAATGATTCAGCACCCGGCGGTACAGCGTATCTGTAATCGCGATTATTCGTCGCTGT
TCACCGAACCCCGATAG

Upstream 100 bases:

>100_bases
CCTCATACTGCGTCAGCGCGTGACGGATACTCGCCTCGCGGTATAACCTTTCTGCAGGAGAGCCCGCCAGGCTCTCCTGG
ACATTATCAGGGAGAGAAGC

Downstream 100 bases:

>100_bases
CCGGAAGGCGTGGGCTGGCGTGGCTCAGATCGCGCCAGCGTGCGCTACCGGGGGAAGATGATAGGCATAAAAAAACCCGC
TTTCGCGGGTTTCTTTAACA

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADRMFTLSQE
MLDIVNYRKESNLLFDVGVADALSKRLVSGVLDAAVVESEQIHLRCFESTHELLLEQLSQHKLDMIISDCPIDSTQQEGL
FSVKIGECSVSFWCMNPAPTKPFPACLEERRLLIPGRRSMLGRKLLNWINVQGLKVEILGEFDDAALMKAFGAAHNAIFV
APTLYAHDFYHDESIVEIGRMDSVMEEYHAIFAERMIQHPAVQRICNRDYSSLFTEPR

Sequences:

>Translated_298_residues
MSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADRMFTLSQE
MLDIVNYRKESNLLFDVGVADALSKRLVSGVLDAAVVESEQIHLRCFESTHELLLEQLSQHKLDMIISDCPIDSTQQEGL
FSVKIGECSVSFWCMNPAPTKPFPACLEERRLLIPGRRSMLGRKLLNWINVQGLKVEILGEFDDAALMKAFGAAHNAIFV
APTLYAHDFYHDESIVEIGRMDSVMEEYHAIFAERMIQHPAVQRICNRDYSSLFTEPR
>Mature_297_residues
SHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADRMFTLSQEM
LDIVNYRKESNLLFDVGVADALSKRLVSGVLDAAVVESEQIHLRCFESTHELLLEQLSQHKLDMIISDCPIDSTQQEGLF
SVKIGECSVSFWCMNPAPTKPFPACLEERRLLIPGRRSMLGRKLLNWINVQGLKVEILGEFDDAALMKAFGAAHNAIFVA
PTLYAHDFYHDESIVEIGRMDSVMEEYHAIFAERMIQHPAVQRICNRDYSSLFTEPR

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=90.1694915254237, Blast_Score=565, Evalue=1e-163,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=23.7903225806452, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34035; Mature: 33903

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEP
CCCCCCCEEEEEEEEEECCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SELGELVFRYADRMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSGVLDAAVVESE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC
QIHLRCFESTHELLLEQLSQHKLDMIISDCPIDSTQQEGLFSVKIGECSVSFWCMNPAPT
HHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCCCC
KPFPACLEERRLLIPGRRSMLGRKLLNWINVQGLKVEILGEFDDAALMKAFGAAHNAIFV
CCCHHHHHCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEE
APTLYAHDFYHDESIVEIGRMDSVMEEYHAIFAERMIQHPAVQRICNRDYSSLFTEPR
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
SHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEP
CCCCCCEEEEEEEEEECCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SELGELVFRYADRMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSGVLDAAVVESE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC
QIHLRCFESTHELLLEQLSQHKLDMIISDCPIDSTQQEGLFSVKIGECSVSFWCMNPAPT
HHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCCCC
KPFPACLEERRLLIPGRRSMLGRKLLNWINVQGLKVEILGEFDDAALMKAFGAAHNAIFV
CCCHHHHHCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEE
APTLYAHDFYHDESIVEIGRMDSVMEEYHAIFAERMIQHPAVQRICNRDYSSLFTEPR
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]