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The map label for this gene is yifK [H]

Identifier: 238892400

GI number: 238892400

Start: 162319

End: 163704

Strand: Direct

Name: yifK [H]

Synonym: KP1_0158

Alternate gene names: 238892400

Gene position: 162319-163704 (Clockwise)

Preceding gene: 238892399

Following gene: 238892406

Centisome position: 3.09

GC content: 57.0

Gene sequence:

>1386_bases
ATGACTGAGAAAAAAGCGGAGCTCCAGCGTGGACTGGAGGCCCGGCATATTGAACTGATCGCCCTTGGCGGGACGATTGG
CGTGGGGTTGTTTATGGGGGCGGCCAGTACCTTGAAATGGGCTGGGCCTTCCGTGCTGCTGGCGTATATTATCGCTGGCC
TGTTCGTCTTTTTCATTATGCGCTCAATGGGCGAAATGCTGTTCCTTGAGCCTGTCACTGGCTCCTTCGCGGTGTATGCG
CATCGCTATATGAGCCCCTTCTTCGGCTATCTGACCGCGTGGTCCTACTGGTTTATGTGGATGGCGGTGGGGATCTCGGA
GATTACCGCCATCGGGGTCTATGTGCAGTTCTGGTTCCCGGAGATGGCGCAGTGGATCCCGGCGTTGATTGCCGTGGGGC
TGGTGGCGTTGGCTAACCTCGCGGCGGTCCGGCTATACGGTGAAATCGAGTTCTGGTTCGCCATGATAAAAGTGACCACC
ATTATCGTGATGATCGTCGTGGGTCTGGGCGTCATTTTCTTCGGCTTTGGCAACGGCGGCCACTCCATCGGTTTTGGTAA
TCTCACCGAACATGGTGGTTTCTTTGCTGGCGGCTGGAAGGGCTTCCTGACGGCGCTGTGTATCGTGGTCGCGTCCTATC
AGGGGGTGGAGCTCATCGGCATTACCGCAGGTGAAGCGAAAAACCCGCAGGTGACGCTGCGCAGCGCGGTGGGCAAAGTG
CTGTGGCGGATCCTGATTTTCTACGTCGGCGCGATTTTCGTTATCGTCACTATCTTCCCGTGGGATCAAATCGGCTCCAA
CGGCAGCCCGTTCGTACTGACGTTTGCCAAAATCGGTATTACCGCGGCGGCGGGAATTATCAACTTCGTGGTGCTGACGG
CAGCGCTTTCCGGCTGCAACAGCGGAATGTACAGCTGCGGACGTATGCTGTACGCCCTGGCGAAGAACCGTCAGCTGCCG
GCGGCGATCGGTAAGGTATCGCGCAACGGCGTTCCGTCCGTCGGTGTGGCGCTGTCGATTCTAATCCTGCTGGTGGGCTC
CTGCCTGAATTACATTATTCCTAATCCGCAGCGGGTGTTCGTCTATGTCTATAGCGCCAGCGTCCTGCCGGGGATGGTGC
CCTGGTTTGTGATCCTGATTAGTCAGCTGCGTTTCCGTCGCGTGCATCAGGCGGCGATTGCCAGCCATCCGTTCCGTTCG
CTGCTGTTTCCGTGGGCCAACTATTTCACGATGGCCTTCCTGATCTGCGTGCTGGTCGGGATGGGACTGAATGATGAAAC
CCGCATGTCGCTCTTCGTCGGCATTATTTTTCTGGCCGCCGTCACCCTGATTTATAAGGTGTTTGGCCTCGGAAGACAGG
GGCAAGTCAATAATACGGCTGAATAA

Upstream 100 bases:

>100_bases
CTTCATACGCGCCGGGGAGACCTGCGCGTCGGCAAGGCTATGGTTTCAGTTAATAACAATAACCGGGAGTACCCGGAATA
CGGCAAACACAAGAGGATAT

Downstream 100 bases:

>100_bases
CCGTCAAAATGAACAAAGCATGAGCAAACGATAATTTTCTTTAAAAAGGCACTAGACAGCGGGGTAGGAAGTCCGTATTA
TCCGACCCCGCAACGGCGCT

Product: putative transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTEKKAELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVVGLGVIFFGFGNGGHSIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWDQIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAIGKVSRNGVPSVGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRVHQAAIASHPFRS
LLFPWANYFTMAFLICVLVGMGLNDETRMSLFVGIIFLAAVTLIYKVFGLGRQGQVNNTAE

Sequences:

>Translated_461_residues
MTEKKAELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVVGLGVIFFGFGNGGHSIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWDQIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAIGKVSRNGVPSVGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRVHQAAIASHPFRS
LLFPWANYFTMAFLICVLVGMGLNDETRMSLFVGIIFLAAVTLIYKVFGLGRQGQVNNTAE
>Mature_460_residues
TEKKAELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAH
RYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTI
IVMIVVGLGVIFFGFGNGGHSIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL
WRILIFYVGAIFVIVTIFPWDQIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA
AIGKVSRNGVPSVGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRVHQAAIASHPFRSL
LFPWANYFTMAFLICVLVGMGLNDETRMSLFVGIIFLAAVTLIYKVFGLGRQGQVNNTAE

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=91.7570498915401, Blast_Score=825, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=440, Percent_Identity=43.6363636363636, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1790653, Length=459, Percent_Identity=38.9978213507625, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1786302, Length=431, Percent_Identity=39.907192575406, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1786602, Length=437, Percent_Identity=45.9954233409611, Blast_Score=334, Evalue=8e-93,
Organism=Escherichia coli, GI1788480, Length=437, Percent_Identity=39.3592677345538, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI87081915, Length=392, Percent_Identity=38.5204081632653, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI87081708, Length=469, Percent_Identity=35.8208955223881, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI1789017, Length=465, Percent_Identity=32.9032258064516, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI2367353, Length=441, Percent_Identity=24.7165532879819, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082250, Length=342, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=442, Percent_Identity=35.0678733031674, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6320772, Length=466, Percent_Identity=32.618025751073, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6324924, Length=440, Percent_Identity=31.1363636363636, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6324059, Length=451, Percent_Identity=32.1507760532151, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324990, Length=484, Percent_Identity=29.3388429752066, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322892, Length=439, Percent_Identity=30.0683371298405, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319824, Length=437, Percent_Identity=28.1464530892449, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6321629, Length=417, Percent_Identity=27.0983213429257, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322967, Length=410, Percent_Identity=29.2682926829268, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6319608, Length=429, Percent_Identity=29.3706293706294, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6321053, Length=422, Percent_Identity=28.436018957346, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6319543, Length=399, Percent_Identity=29.3233082706767, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=30.2267002518892, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6324981, Length=412, Percent_Identity=29.6116504854369, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=438, Percent_Identity=23.972602739726, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319542, Length=436, Percent_Identity=25.6880733944954, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320251, Length=401, Percent_Identity=26.4339152119701, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320364, Length=490, Percent_Identity=24.2857142857143, Blast_Score=106, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50144; Mature: 50013

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKAELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVVGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
HSIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCCHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWDQIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAIGKVSRNGVPSVGVALSILILLVGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRVHQAAIASHPFRSLLFPWANYFTMAFLICVLVG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
MGLNDETRMSLFVGIIFLAAVTLIYKVFGLGRQGQVNNTAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TEKKAELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVVGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
HSIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCCHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWDQIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAIGKVSRNGVPSVGVALSILILLVGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRVHQAAIASHPFRSLLFPWANYFTMAFLICVLVG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
MGLNDETRMSLFVGIIFLAAVTLIYKVFGLGRQGQVNNTAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]