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The map label for this gene is argE [H]

Identifier: 238892354

GI number: 238892354

Start: 107581

End: 108771

Strand: Reverse

Name: argE [H]

Synonym: KP1_0109

Alternate gene names: 238892354

Gene position: 108771-107581 (Counterclockwise)

Preceding gene: 238892359

Following gene: 238892353

Centisome position: 2.07

GC content: 59.7

Gene sequence:

>1191_bases
ATGAATATTGATACTATCACGACCCAAGGTGTGTCAACAATGAAAAACAATTTACCGCCCTTTATCGAGATTTACCGCGC
GTTGATCGCCACACCATCCATCAGCGCGACTGAAGAGGCTCTCGATCAAAGCAATGAGTCTTTAATCAATTTGCTGGCAG
GCTGGTTCCGCGATCTCGGCTTCAATGTTGAGATACAGCCGGTGCCGGATACGCGCCATAAATTCAACCTGCTGGCCAGC
ACCGGACACGGCGCCGGCGGCCTGCTGCTCGCCGGGCATACCGATACCGTGCCGTTCGATGATGGCCGCTGGACGCGCGA
CCCGTTCACCCTCACCGAACACGATAACAAGCTCTACGGCCTCGGCACGGCCGATATGAAAGGCTTCTTCGCCTTTATTC
TCGACGCCCTGCGCGATGTCGACGTCACCACGCTGAAAAAGCCGCTATATATTCTGGCCACTGCCGACGAAGAGACCAGC
ATGGCCGGCGCGCGCTACTTTGCCGAAACCACCCGGCTGCGCCCGGACTGCGCCATCATCGGCGAGCCCACCTCCCTGCA
GCCGATCCGCGCCCACAAAGGCCATATGTCCAACGCGATCCGTATTCAGGGCCAGTCCGGCCACTCCAGCGATCCGGCGC
GCGGGGTCAACGCGATTGAGCTGATGCACGACGCCATCGGCCGGATTATGCAGTTGCGCGATCTGCTAAAAGAGCGCTAT
CACTTCGAAGCGTTTACGGTCCCTTACCCAACCCTCAACCTGGGCGCTATCCATGGCGGCGATGCCTCAAACCGTATCTG
CGCCTGCTGTGAACTGCATATGGATATCCGCCCGCTGCCGGGGATGACCCTAAACGATCTTAATGGTCTGTTGGGCGAGG
CGCTGGCCCCGGTCAGCGAACGCTGGCCGGGCCGCCTGACGGTCTCTGAGCTGCATCCGCCGATCCCCGGCTACGAGTGC
CCGCCGGACCATAAGCTGGTGCAGGTGGTCGAGAAACTGCTTGGCGCGCAGACCGACGTGGTGAACTACTGCACCGAAGC
GCCGTTTATCCAGACGCTGTGTCCGACGCTGGTTCTCGGCCCGGGCTCCATCAATCAGGCCCATCAGCCTGACGAGTATC
TGGAGACGCGCTTTATCAAGCCGACCCGGGAGCTGATTAGCCAGGTGGTTCATCACTTCTGCTGGCACTAA

Upstream 100 bases:

>100_bases
GCACCCACAATCAGCGTATTTAACATTGGAAGCGCATCTCCTTACATTCGATGGGTTTTCTTACGCTCAACGATATTGTA
TTTTTATTCACAATAAATGC

Downstream 100 bases:

>100_bases
AATCGCCCTCTTTTTCCGCCCCGTTCCCCCGGGGCGGAACGGTGACGATCGTCACATTTCCATAAGCGATGCTTATCCAG
CGCCCCCTGAATTAAATTTC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNIDTITTQGVSTMKNNLPPFIEIYRALIATPSISATEEALDQSNESLINLLAGWFRDLGFNVEIQPVPDTRHKFNLLAS
TGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTTLKKPLYILATADEETS
MAGARYFAETTRLRPDCAIIGEPTSLQPIRAHKGHMSNAIRIQGQSGHSSDPARGVNAIELMHDAIGRIMQLRDLLKERY
HFEAFTVPYPTLNLGAIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLGEALAPVSERWPGRLTVSELHPPIPGYEC
PPDHKLVQVVEKLLGAQTDVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELISQVVHHFCWH

Sequences:

>Translated_396_residues
MNIDTITTQGVSTMKNNLPPFIEIYRALIATPSISATEEALDQSNESLINLLAGWFRDLGFNVEIQPVPDTRHKFNLLAS
TGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTTLKKPLYILATADEETS
MAGARYFAETTRLRPDCAIIGEPTSLQPIRAHKGHMSNAIRIQGQSGHSSDPARGVNAIELMHDAIGRIMQLRDLLKERY
HFEAFTVPYPTLNLGAIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLGEALAPVSERWPGRLTVSELHPPIPGYEC
PPDHKLVQVVEKLLGAQTDVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELISQVVHHFCWH
>Mature_396_residues
MNIDTITTQGVSTMKNNLPPFIEIYRALIATPSISATEEALDQSNESLINLLAGWFRDLGFNVEIQPVPDTRHKFNLLAS
TGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTTLKKPLYILATADEETS
MAGARYFAETTRLRPDCAIIGEPTSLQPIRAHKGHMSNAIRIQGQSGHSSDPARGVNAIELMHDAIGRIMQLRDLLKERY
HFEAFTVPYPTLNLGAIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLGEALAPVSERWPGRLTVSELHPPIPGYEC
PPDHKLVQVVEKLLGAQTDVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELISQVVHHFCWH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=383, Percent_Identity=91.3838120104439, Blast_Score=737, Evalue=0.0,
Organism=Escherichia coli, GI1789236, Length=373, Percent_Identity=26.8096514745308, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788816, Length=264, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551016, Length=385, Percent_Identity=25.1948051948052, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43757; Mature: 43757

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDTITTQGVSTMKNNLPPFIEIYRALIATPSISATEEALDQSNESLINLLAGWFRDLG
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCC
FNVEIQPVPDTRHKFNLLASTGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYG
CCEEEEECCCCCHHEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEE
LGTADMKGFFAFILDALRDVDVTTLKKPLYILATADEETSMAGARYFAETTRLRPDCAII
CCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
GEPTSLQPIRAHKGHMSNAIRIQGQSGHSSDPARGVNAIELMHDAIGRIMQLRDLLKERY
CCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HFEAFTVPYPTLNLGAIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLGEALAPVSE
CCEEEECCCCCCEECEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHH
RWPGRLTVSELHPPIPGYECPPDHKLVQVVEKLLGAQTDVVNYCTEAPFIQTLCPTLVLG
CCCCCEEHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHEEC
PGSINQAHQPDEYLETRFIKPTRELISQVVHHFCWH
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIDTITTQGVSTMKNNLPPFIEIYRALIATPSISATEEALDQSNESLINLLAGWFRDLG
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCC
FNVEIQPVPDTRHKFNLLASTGHGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDNKLYG
CCEEEEECCCCCHHEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEE
LGTADMKGFFAFILDALRDVDVTTLKKPLYILATADEETSMAGARYFAETTRLRPDCAII
CCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
GEPTSLQPIRAHKGHMSNAIRIQGQSGHSSDPARGVNAIELMHDAIGRIMQLRDLLKERY
CCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HFEAFTVPYPTLNLGAIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLGEALAPVSE
CCEEEECCCCCCEECEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHH
RWPGRLTVSELHPPIPGYECPPDHKLVQVVEKLLGAQTDVVNYCTEAPFIQTLCPTLVLG
CCCCCEEHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHEEC
PGSINQAHQPDEYLETRFIKPTRELISQVVHHFCWH
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA