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The map label for this gene is yiaY [H]

Identifier: 238892314

GI number: 238892314

Start: 62271

End: 63419

Strand: Reverse

Name: yiaY [H]

Synonym: KP1_0065

Alternate gene names: 238892314

Gene position: 63419-62271 (Counterclockwise)

Preceding gene: 238892315

Following gene: 238892313

Centisome position: 1.21

GC content: 62.23

Gene sequence:

>1149_bases
ATGAGTTTTATGTTGGCACTACCTAAAATCAGCCTCCACGGCGCAGGCGCGATCGGTGATATGGTCAAGCTGGTAGCGGG
CAAACAGTGGGGCAAGGCGCTGATCGTCACCGACGGTCAGCTGGTGAAGCTGGGCCTGCTGGACAGCCTGTTCGCCGCGC
TGGATGAACAGCAGATGGCTTATCAGCTATTTGACGAGGTATTCCCCAACCCCACCGAAGCGCTGGTGCAGCAAGGCTAT
GCGGCTTACCAGGCGGCCCGCTGCGATTACCTGATCGCCTTCGGCGGCGGTAGCCCGATTGATACCGCCAAAGCGATAAA
AATCCTCACCGCCAACCCAGGCCTCTCCACCGCCTACTCCGGCGTCGGCAAAGTGAAAAACGCTGGCGTGCCGCTGGTGG
CCATCAATACCACCGCCGGCACGGCGGCGGAGATGACCAGCAACGCGGTAATTATCGATAGCGAGCGGCAGGTGAAAGAG
GTGATTATCGACCCGAACCTGATCCCGGATATCGCCGTCGACGACGCCAGCGTGATGCTCGACATTCCGCCAGCCGTTAC
CGCCGCCACCGGCATGGATGCCCTGACCCACGCCATCGAGGCCTTTGTCTCCGTTGGCGCCCATCCGCTGACCGACGCCA
ACGCCCTCGAGGCCATTCGTCTGATTAACCTGTGGCTGCCGAAAGCGGTAGACGATGGGCACGATCTGCAGGCCCGCGAG
CAGATGGCCTTTGGCCAGTATCTGGCAGGCATGGCGTTCAACAGCGCCGGTCTCGGGCTGGTACATGCCCTGGCCCATCA
GCCTGGCGCCACCCACAACCTGCCGCACGGGGTATGCAACGCCATCCTGCTGCCGATCATCGAAAACTTTAACCGCCCGA
ACGCGGTGGCGCGCTTTGCCCGCGTGGCGCAGGCGATGGGCGTCGATACTCGCGGCATGAGCGATGAAGCTGCCAGCATG
GAGGCCATCAATGCCATCCGCACGCTGAGCAAACGCGTAGGGATCCCCCAGGGTTTTAGCCAGCTTGGCGTCAGCAAAGC
CGATATCGAAGGCTGGCTGGATAAAGCGCTGGCCGACCCATGCGCGCCGTGTAACCCGCGCCCCGCCAGCCGCGATGAGG
TTCGCGAGCTCTATCTGGAGGCCTTATGA

Upstream 100 bases:

>100_bases
GACGATGTTAATTTCCCCCTCACCCTGGCCCCCTCCCTGCGGGAGAAGGTCGGGGTGAGGGGAAACGGATTTCCCAAAAT
CAACATTAAGGAGAATTATC

Downstream 100 bases:

>100_bases
TCCGTAAAGCCTTCGTCATGCAGGTGAACCCCGACGCGCACGAGGAGTACCAGCGCCGCCATAACCCCATCTGGCCGGAG
CTGGAGGCAGTGTTGAAGGA

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSFMLALPKISLHGAGAIGDMVKLVAGKQWGKALIVTDGQLVKLGLLDSLFAALDEQQMAYQLFDEVFPNPTEALVQQGY
AAYQAARCDYLIAFGGGSPIDTAKAIKILTANPGLSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSERQVKE
VIIDPNLIPDIAVDDASVMLDIPPAVTAATGMDALTHAIEAFVSVGAHPLTDANALEAIRLINLWLPKAVDDGHDLQARE
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIIENFNRPNAVARFARVAQAMGVDTRGMSDEAASM
EAINAIRTLSKRVGIPQGFSQLGVSKADIEGWLDKALADPCAPCNPRPASRDEVRELYLEAL

Sequences:

>Translated_382_residues
MSFMLALPKISLHGAGAIGDMVKLVAGKQWGKALIVTDGQLVKLGLLDSLFAALDEQQMAYQLFDEVFPNPTEALVQQGY
AAYQAARCDYLIAFGGGSPIDTAKAIKILTANPGLSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSERQVKE
VIIDPNLIPDIAVDDASVMLDIPPAVTAATGMDALTHAIEAFVSVGAHPLTDANALEAIRLINLWLPKAVDDGHDLQARE
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIIENFNRPNAVARFARVAQAMGVDTRGMSDEAASM
EAINAIRTLSKRVGIPQGFSQLGVSKADIEGWLDKALADPCAPCNPRPASRDEVRELYLEAL
>Mature_381_residues
SFMLALPKISLHGAGAIGDMVKLVAGKQWGKALIVTDGQLVKLGLLDSLFAALDEQQMAYQLFDEVFPNPTEALVQQGYA
AYQAARCDYLIAFGGGSPIDTAKAIKILTANPGLSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSERQVKEV
IIDPNLIPDIAVDDASVMLDIPPAVTAATGMDALTHAIEAFVSVGAHPLTDANALEAIRLINLWLPKAVDDGHDLQAREQ
MAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIIENFNRPNAVARFARVAQAMGVDTRGMSDEAASME
AINAIRTLSKRVGIPQGFSQLGVSKADIEGWLDKALADPCAPCNPRPASRDEVRELYLEAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=386, Percent_Identity=26.4248704663212, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI48994951, Length=376, Percent_Identity=45.2127659574468, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=44.1253263707572, Blast_Score=297, Evalue=9e-82,
Organism=Escherichia coli, GI87082107, Length=374, Percent_Identity=39.572192513369, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787493, Length=380, Percent_Identity=32.1052631578947, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789386, Length=367, Percent_Identity=27.2479564032698, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=393, Percent_Identity=27.2264631043257, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321181, Length=370, Percent_Identity=42.7027027027027, Blast_Score=296, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24657991, Length=390, Percent_Identity=27.4358974358974, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40225; Mature: 40093

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFMLALPKISLHGAGAIGDMVKLVAGKQWGKALIVTDGQLVKLGLLDSLFAALDEQQMA
CCCEEECCCEEECCCCHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHH
YQLFDEVFPNPTEALVQQGYAAYQAARCDYLIAFGGGSPIDTAKAIKILTANPGLSTAYS
HHHHHHHCCCHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHEEEEEECCCCCHHHHH
GVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSERQVKEVIIDPNLIPDIAVDDASVML
CCCCCCCCCCCEEEEECCCCCHHHHCCCEEEEECHHHHHHHHCCCCCCCCCEECCCEEEE
DIPPAVTAATGMDALTHAIEAFVSVGAHPLTDANALEAIRLINLWLPKAVDDGHDLQARE
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIIENFNRPNAVARFA
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
RVAQAMGVDTRGMSDEAASMEAINAIRTLSKRVGIPQGFSQLGVSKADIEGWLDKALADP
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCCC
CAPCNPRPASRDEVRELYLEAL
CCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SFMLALPKISLHGAGAIGDMVKLVAGKQWGKALIVTDGQLVKLGLLDSLFAALDEQQMA
CCEEECCCEEECCCCHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHH
YQLFDEVFPNPTEALVQQGYAAYQAARCDYLIAFGGGSPIDTAKAIKILTANPGLSTAYS
HHHHHHHCCCHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHEEEEEECCCCCHHHHH
GVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSERQVKEVIIDPNLIPDIAVDDASVML
CCCCCCCCCCCEEEEECCCCCHHHHCCCEEEEECHHHHHHHHCCCCCCCCCEECCCEEEE
DIPPAVTAATGMDALTHAIEAFVSVGAHPLTDANALEAIRLINLWLPKAVDDGHDLQARE
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIIENFNRPNAVARFA
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
RVAQAMGVDTRGMSDEAASMEAINAIRTLSKRVGIPQGFSQLGVSKADIEGWLDKALADP
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCCC
CAPCNPRPASRDEVRELYLEAL
CCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]