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The map label for this gene is glnL [H]

Identifier: 238892282

GI number: 238892282

Start: 33753

End: 34802

Strand: Reverse

Name: glnL [H]

Synonym: KP1_0029

Alternate gene names: 238892282

Gene position: 34802-33753 (Counterclockwise)

Preceding gene: 238892283

Following gene: 238892281

Centisome position: 0.66

GC content: 58.57

Gene sequence:

>1050_bases
ATGGCAACAGGCACACTGCCCGATGCTGGGCAGATCCTTAACTCCCTTATCAACAGTATTTTACTGGTCGATGATGACCT
GGCTGTGCACTTTGCCAACCCTGCGGCGCAGCAGCTGCTGGCGCAGAGCTCGCGCAAACTGTTTGGCACCCCATTACCTG
AGCTGTTGAGCTATTTTTCGTTGAATATCGGGCTGATGCAGGAGAGCCTGCAGGCGGGCCAGGGGTTTACCGATAACGAA
GTGACCCTGGTTATCGATGGCCGTTCGCACATCCTGTCGTTGACCGCCCAGCGGCTGCCGGAAGGCTTTATTCTGCTGGA
AATGGCGCCGATGGATAATCAGCGCCGCCTGAGCCAGGAGCAGCTGCAGCATGCGCAGCAGGTCGCCGCTCGCGACCTCG
TCCGCGGCCTGGCGCATGAGATAAAAAACCCGTTAGGCGGCCTGCGCGGCGCGGCCCAGCTGCTCAGCAAAGCGCTGCCC
GACCCGGCGCTAACGGAATATACCAAAGTGATCATTGAGCAGGCCGACCGGCTAAGAAATCTGGTCGACCGCCTGCTCGG
ACCACAGCATCCGGGCATGCACGTTACCGAAAGCATCCACAAAGTCGCCGAACGGGTAGTTAAACTGGTTTCCATGGAGT
TGCCGGACAACGTGAAGTTGATCCGCGATTACGACCCCAGCCTACCAGAGCTACCCCACGACCCGGATCAAATTGAACAG
GTGTTGCTGAACATCGTCCGTAATGCGCTGCAGGCTCTGGGGCCGGAAGGGGGCGAAATTATTCTTCGCACCCGCACCGC
TTTCCAGCTGACGCTGCACGGGGTGCGTTATCGCCTCGCCGCCCGCATCGACGTTGAAGATAATGGCCCGGGTATTCCGC
CCCATCTCCAGGATACGCTGTTCTATCCGATGGTCAGCGGCCGCGAAGGCGGTACCGGCCTGGGCTTATCTATCGCCCGT
AGCCTTATCGATCAGCACTCCGGCAAAATTGAATTCACCAGCTGGCCGGGTCATACCGAATTTTCGGTATACCTGCCTAT
TCGGAAGTAG

Upstream 100 bases:

>100_bases
TGGGCTTTTTTCTCCACCAACACGCTGATCTCGCGAGCTTTTTACCGATAAAAAGCTATACTGCACTAAATTGGTGCACT
CATTTTCAGGAGACTGTCGA

Downstream 100 bases:

>100_bases
AGGTGTTTATGCAACGAGGGATAGCCTGGATCGTTGATGACGATAGCTCCATCCGCTGGGTGCTTGAACGCGCGCTCACC
GGAGCCGGCTTGAGCTGCAC

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MATGTLPDAGQILNSLINSILLVDDDLAVHFANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIGLMQESLQAGQGFTDNE
VTLVIDGRSHILSLTAQRLPEGFILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
DPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHVTESIHKVAERVVKLVSMELPDNVKLIRDYDPSLPELPHDPDQIEQ
VLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGVRYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIAR
SLIDQHSGKIEFTSWPGHTEFSVYLPIRK

Sequences:

>Translated_349_residues
MATGTLPDAGQILNSLINSILLVDDDLAVHFANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIGLMQESLQAGQGFTDNE
VTLVIDGRSHILSLTAQRLPEGFILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
DPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHVTESIHKVAERVVKLVSMELPDNVKLIRDYDPSLPELPHDPDQIEQ
VLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGVRYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIAR
SLIDQHSGKIEFTSWPGHTEFSVYLPIRK
>Mature_348_residues
ATGTLPDAGQILNSLINSILLVDDDLAVHFANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIGLMQESLQAGQGFTDNEV
TLVIDGRSHILSLTAQRLPEGFILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPD
PALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHVTESIHKVAERVVKLVSMELPDNVKLIRDYDPSLPELPHDPDQIEQV
LLNIVRNALQALGPEGGEIILRTRTAFQLTLHGVRYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARS
LIDQHSGKIEFTSWPGHTEFSVYLPIRK

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=93.9828080229226, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI1788549, Length=355, Percent_Identity=27.6056338028169, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=30.2788844621514, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=31.1688311688312, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=351, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790567, Length=342, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=270, Percent_Identity=28.1481481481481, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=250, Percent_Identity=27.2, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=27.6018099547511, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=28.5123966942149, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38427; Mature: 38296

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGTLPDAGQILNSLINSILLVDDDLAVHFANPAAQQLLAQSSRKLFGTPLPELLSYFS
CCCCCCCCHHHHHHHHHHHHEEECCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNIGLMQESLQAGQGFTDNEVTLVIDGRSHILSLTAQRLPEGFILLEMAPMDNQRRLSQE
HHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
QLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVDRLLGPQHPGMHVTESIHKVAERVVKLVSMELPDNVKLIRDYDPSLPELPHDPDQIEQ
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHH
VLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGVRYRLAARIDVEDNGPGIPPHLQDTL
HHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHH
FYPMVSGREGGTGLGLSIARSLIDQHSGKIEFTSWPGHTEFSVYLPIRK
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure 
ATGTLPDAGQILNSLINSILLVDDDLAVHFANPAAQQLLAQSSRKLFGTPLPELLSYFS
CCCCCCCHHHHHHHHHHHHEEECCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNIGLMQESLQAGQGFTDNEVTLVIDGRSHILSLTAQRLPEGFILLEMAPMDNQRRLSQE
HHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
QLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVDRLLGPQHPGMHVTESIHKVAERVVKLVSMELPDNVKLIRDYDPSLPELPHDPDQIEQ
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHH
VLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGVRYRLAARIDVEDNGPGIPPHLQDTL
HHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHH
FYPMVSGREGGTGLGLSIARSLIDQHSGKIEFTSWPGHTEFSVYLPIRK
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]