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The map label for this gene is rbsK [H]

Identifier: 238892267

GI number: 238892267

Start: 11570

End: 12499

Strand: Direct

Name: rbsK [H]

Synonym: KP1_0011

Alternate gene names: 238892267

Gene position: 11570-12499 (Clockwise)

Preceding gene: 238892266

Following gene: 238892268

Centisome position: 0.22

GC content: 60.65

Gene sequence:

>930_bases
ATGAAAACTGCAGGCAAACTTGTCGTCCTTGGCAGTATCAATGCCGATCACATTCTTAACCTTGACGCTTTCCCGACGCC
GGGCGAAACCGTCACCGGCCACCATTATCAGGTGGCGTTCGGTGGAAAAGGGGCCAACCAGGCGGTGGCCGCCGGGCGCA
GCGGAGCGGATATCGCGTTTATCGCCTGCACCGGCGATGACGATATCGGTGAACGCATCCGTCGTCAGCTGGCGAGCGAT
AAAATCGACGTGGCGCCCGTGCGCGCGGTTGCCGGGGAAGCGACCGGGGTGGCATTAATTTTCGTTAACGCCGAAGGTGA
GAATGTCATCGGTATTCATGCCGGCGCCAATGCGGCGCTTTCCGTCTCCCAGGTTGAGGCGGAAAAAGAGCGTATCGCCA
GCGCACAGGCGTTGTTGATGCAGCTGGAGTCGCCGCTGGAGAGCGTCATAGCGGCGGCGAAAATCGCCCATCACCATCAC
ACCACCGTGGTGCTGAACCCCGCGCCAGCGCGTGAACTACCGGATGAACTGCTGGCGCTGGTGGATATTATTACCCCTAA
CGAAACCGAAGCGGAAAAGCTGACCGGTATTCGCGTTGAGAGTGACGAAGATGCGGCAAAAGCCGCCAACGTGCTGCATG
CCAAAGGCATTGGTACGGTGATGATCACCCTCGGCAGCCGCGGCGTCTGGCTCAGTGCCGAAGGCGAAAGCCGCCGGATC
CCAGGGTTTCGCGTACAGGCCATTGATACTATCGCGGCCGGTGATACCTTTAACGGCGCGCTGGTGACCGCGCTGCTGGA
AGGGACCGCCCTGCCGGAGGCGATTCGCTTTGCGCATGCCGCAGCGGCGATCGCCGTAACCCGCAAAGGCGCTCAGCCGT
CCGTGCCGTGGCGCACAGAGATCGATGAATTTTTAGCGCAACAGGGGTAA

Upstream 100 bases:

>100_bases
GCGATTCGGACTGGCAACGGTCCGAGGGACAATATAAAAAAAGAAAAGCAGGGCATGCGCCACCGGATCCCGGTGGCGCG
CTTTCCCGGGAACAGAAATG

Downstream 100 bases:

>100_bases
TGCTTGGCTACGATGAAAGATGTGGCCCGCATCGCGGGCGTTTCCACATCGACGGTGTCACACGTCATCAATAAGGACCG
CTTTGTCAGCGAGGCGATTA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKTAGKLVVLGSINADHILNLDAFPTPGETVTGHHYQVAFGGKGANQAVAAGRSGADIAFIACTGDDDIGERIRRQLASD
KIDVAPVRAVAGEATGVALIFVNAEGENVIGIHAGANAALSVSQVEAEKERIASAQALLMQLESPLESVIAAAKIAHHHH
TTVVLNPAPARELPDELLALVDIITPNETEAEKLTGIRVESDEDAAKAANVLHAKGIGTVMITLGSRGVWLSAEGESRRI
PGFRVQAIDTIAAGDTFNGALVTALLEGTALPEAIRFAHAAAAIAVTRKGAQPSVPWRTEIDEFLAQQG

Sequences:

>Translated_309_residues
MKTAGKLVVLGSINADHILNLDAFPTPGETVTGHHYQVAFGGKGANQAVAAGRSGADIAFIACTGDDDIGERIRRQLASD
KIDVAPVRAVAGEATGVALIFVNAEGENVIGIHAGANAALSVSQVEAEKERIASAQALLMQLESPLESVIAAAKIAHHHH
TTVVLNPAPARELPDELLALVDIITPNETEAEKLTGIRVESDEDAAKAANVLHAKGIGTVMITLGSRGVWLSAEGESRRI
PGFRVQAIDTIAAGDTFNGALVTALLEGTALPEAIRFAHAAAAIAVTRKGAQPSVPWRTEIDEFLAQQG
>Mature_309_residues
MKTAGKLVVLGSINADHILNLDAFPTPGETVTGHHYQVAFGGKGANQAVAAGRSGADIAFIACTGDDDIGERIRRQLASD
KIDVAPVRAVAGEATGVALIFVNAEGENVIGIHAGANAALSVSQVEAEKERIASAQALLMQLESPLESVIAAAKIAHHHH
TTVVLNPAPARELPDELLALVDIITPNETEAEKLTGIRVESDEDAAKAANVLHAKGIGTVMITLGSRGVWLSAEGESRRI
PGFRVQAIDTIAAGDTFNGALVTALLEGTALPEAIRFAHAAAAIAVTRKGAQPSVPWRTEIDEFLAQQG

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=36.4864864864865, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI32484973, Length=266, Percent_Identity=28.1954887218045, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI32484975, Length=266, Percent_Identity=28.1954887218045, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1790193, Length=308, Percent_Identity=82.4675324675325, Blast_Score=489, Evalue=1e-140,
Organism=Escherichia coli, GI87081971, Length=301, Percent_Identity=27.5747508305648, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082343, Length=302, Percent_Identity=28.476821192053, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788491, Length=297, Percent_Identity=24.5791245791246, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788484, Length=281, Percent_Identity=24.9110320284698, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788417, Length=315, Percent_Identity=24.7619047619048, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=308, Percent_Identity=39.9350649350649, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=31.0030395136778, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=37.953795379538, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=33, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32091; Mature: 32091

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAGKLVVLGSINADHILNLDAFPTPGETVTGHHYQVAFGGKGANQAVAAGRSGADIAF
CCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEE
IACTGDDDIGERIRRQLASDKIDVAPVRAVAGEATGVALIFVNAEGENVIGIHAGANAAL
EEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCEE
SVSQVEAEKERIASAQALLMQLESPLESVIAAAKIAHHHHTTVVLNPAPARELPDELLAL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
VDIITPNETEAEKLTGIRVESDEDAAKAANVLHAKGIGTVMITLGSRGVWLSAEGESRRI
HHEECCCCCCHHHHEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCC
PGFRVQAIDTIAAGDTFNGALVTALLEGTALPEAIRFAHAAAAIAVTRKGAQPSVPWRTE
CCEEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHEEEEEECCCCCCCCCHHH
IDEFLAQQG
HHHHHHCCC
>Mature Secondary Structure
MKTAGKLVVLGSINADHILNLDAFPTPGETVTGHHYQVAFGGKGANQAVAAGRSGADIAF
CCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEE
IACTGDDDIGERIRRQLASDKIDVAPVRAVAGEATGVALIFVNAEGENVIGIHAGANAAL
EEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCEE
SVSQVEAEKERIASAQALLMQLESPLESVIAAAKIAHHHHTTVVLNPAPARELPDELLAL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
VDIITPNETEAEKLTGIRVESDEDAAKAANVLHAKGIGTVMITLGSRGVWLSAEGESRRI
HHEECCCCCCHHHHEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCC
PGFRVQAIDTIAAGDTFNGALVTALLEGTALPEAIRFAHAAAAIAVTRKGAQPSVPWRTE
CCEEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHEEEEEECCCCCCCCCHHH
IDEFLAQQG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]