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The map label for this gene is oxaA [H]

Identifier: 238028969

GI number: 238028969

Start: 3903558

End: 3905219

Strand: Reverse

Name: oxaA [H]

Synonym: bglu_1g34380

Alternate gene names: 238028969

Gene position: 3905219-3903558 (Counterclockwise)

Preceding gene: 238028970

Following gene: 238028966

Centisome position: 99.97

GC content: 64.02

Gene sequence:

>1662_bases
ATGGATATCAAACGCACCGTCCTATGGGTGATCTTCTTCATGTCAGCGGTCATGCTGTTCGACAACTGGCAGCGTGCCCA
TGGACGCCAGTCGATGTTCTTCCCGAACGTCACGCAGACCAACGTCGCGGCCTCCAAGGGCGGCGCCGACACCGGCGCTT
CGGCGGCGAGCGGCGCGACGGCAGCCCTGCCGGCCGCCTCGACCCAGGCGCCCGCGGCCACCACGCCGATCGCCCAGGCG
CAACTCGTGCCGTTCTCGACCGACGTCTATGACGGCGAGATCGACACGCGCGGCGGCACGCTGACGAAGCTGACGCTGAA
GAAGGAGGGCGACGGCAAGCAGCCGGACCTGTTCGTCACGCTGTTCGACCACACCAAGGACCACACCTACCTGGCACGCA
CCGGCGTGACGGGCGGCAACTTCCCGAACCACAACGACCTGTTCACGCCGCTGAGCGGCCCGCGCTCGCTCGCCGCCGGC
CAGGACACGCTGAAGCTGTCGTTCGAGTCGCAGGAAAAGGGTGGCGTGAAGGTCGTGAAGACCTACACGTTCACGCGCGG
CAGCTACGTGATCGGCGTCGACACGAAGATCGAAAACGTCGGCACCGCCCCCGTCACGCCCACCGTCTACATGGAAATCG
TGCGCGACAGCACGCCGGTGGAAACGCCGCTGTTCTCGCATACGTTCCTCGGGCCGGCGGTCTACACCGATCAGAAGCAC
TTCCAGAAGATCACCTTCAGCGACATCGACAAGAACAAGGCCGAGTACGTCACCTCGGCGGACAACGGCTGGGTCGCGAT
GGTGCAGCACTACTTCGCGTCGGCCTGGATTCCGCAGGCGGGCGTCAAGCGCGATATCTACGTCGAGAAGATCGACCCGT
CGCTGTACCGCATCGGCGTGAAGGAGCCGGTCAAGACGATCGAGCCGGGCCAGTCGGCCGACGTGTCCGCACGCCTGTTC
GCCGGGCCGGAGGAGGAGCGCGTGCTCGAGGGCATCGCCCCGGGCCTCGACCTCGTGAAGGACTACGGCTGGGTCACGAT
CATCGCCAAGCCGCTGTTCTGGCTGCTGCAGAAGATCCACGGCTATGTGGGCAACTGGGGCTGGTCGATCGTGCTGCTGA
CGGTGCTGATCAAGGCCGTGTTCTTCCCGCTGTCGGCAGCCAGCTACAAGTCGATGGCGCGCATGAAGGAAATCACGCCG
CGCATGCAGCAGCTGCGCGAGCGCTTCAAGAGCGATCCGCAAAAGATGAACGCGGCGCTGATGGAGCTCTACAAGACCGA
GAAGGTGAACCCGTTCGGCGGCTGCCTGCCGGTGGTGATCCAGATCCCGGTGTTCATCTCGCTGTATTGGGTGCTGCTGG
CCTCGGTCGAAATGCGCGGCGCGCCCTGGATTCTCTGGATCCACGACCTGTCGCAGCGTGATCCGTACTTCATCCTGCCG
GTGCTGATGGCCGGCTCGATGTTCCTGCAGACGCGCCTGAATCCGACGCCGCCGGACCCGGTCCAGGCCAAGATGATGAT
GTTCATGCCGATCGCGTTCTCGGTGATGTTCTTCTTCTTCCCGGCGGGCCTCGTGCTGTACTACGTCGTCAACAACGTGC
TGTCGATCGCGCAGCAGTACTACATCACGCGGGCGATCGGCAACAAGAAGAAAGCCACCTGA

Upstream 100 bases:

>100_bases
CGTTTTCCGCGGGGGGCGTCGATCTGGTTCCGCCTCCCAACCCCGATACCCGCGCTCCAACCGAAGCTGAAGCGCCGTCC
CATCGACTCTGAGACAACGC

Downstream 100 bases:

>100_bases
TGGCCGCGCGGCGCGGCGGCCTCATGCCGCCTGCCGCCGCGTTTCGCCCCGCATGACGAAAAATGCCCGGCCAGCGCCGG
GCGTTTTTTCATGACAGGCG

Product: membrane protein insertase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MDIKRTVLWVIFFMSAVMLFDNWQRAHGRQSMFFPNVTQTNVAASKGGADTGASAASGATAALPAASTQAPAATTPIAQA
QLVPFSTDVYDGEIDTRGGTLTKLTLKKEGDGKQPDLFVTLFDHTKDHTYLARTGVTGGNFPNHNDLFTPLSGPRSLAAG
QDTLKLSFESQEKGGVKVVKTYTFTRGSYVIGVDTKIENVGTAPVTPTVYMEIVRDSTPVETPLFSHTFLGPAVYTDQKH
FQKITFSDIDKNKAEYVTSADNGWVAMVQHYFASAWIPQAGVKRDIYVEKIDPSLYRIGVKEPVKTIEPGQSADVSARLF
AGPEEERVLEGIAPGLDLVKDYGWVTIIAKPLFWLLQKIHGYVGNWGWSIVLLTVLIKAVFFPLSAASYKSMARMKEITP
RMQQLRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPYFILP
VLMAGSMFLQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRAIGNKKKAT

Sequences:

>Translated_553_residues
MDIKRTVLWVIFFMSAVMLFDNWQRAHGRQSMFFPNVTQTNVAASKGGADTGASAASGATAALPAASTQAPAATTPIAQA
QLVPFSTDVYDGEIDTRGGTLTKLTLKKEGDGKQPDLFVTLFDHTKDHTYLARTGVTGGNFPNHNDLFTPLSGPRSLAAG
QDTLKLSFESQEKGGVKVVKTYTFTRGSYVIGVDTKIENVGTAPVTPTVYMEIVRDSTPVETPLFSHTFLGPAVYTDQKH
FQKITFSDIDKNKAEYVTSADNGWVAMVQHYFASAWIPQAGVKRDIYVEKIDPSLYRIGVKEPVKTIEPGQSADVSARLF
AGPEEERVLEGIAPGLDLVKDYGWVTIIAKPLFWLLQKIHGYVGNWGWSIVLLTVLIKAVFFPLSAASYKSMARMKEITP
RMQQLRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPYFILP
VLMAGSMFLQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRAIGNKKKAT
>Mature_553_residues
MDIKRTVLWVIFFMSAVMLFDNWQRAHGRQSMFFPNVTQTNVAASKGGADTGASAASGATAALPAASTQAPAATTPIAQA
QLVPFSTDVYDGEIDTRGGTLTKLTLKKEGDGKQPDLFVTLFDHTKDHTYLARTGVTGGNFPNHNDLFTPLSGPRSLAAG
QDTLKLSFESQEKGGVKVVKTYTFTRGSYVIGVDTKIENVGTAPVTPTVYMEIVRDSTPVETPLFSHTFLGPAVYTDQKH
FQKITFSDIDKNKAEYVTSADNGWVAMVQHYFASAWIPQAGVKRDIYVEKIDPSLYRIGVKEPVKTIEPGQSADVSARLF
AGPEEERVLEGIAPGLDLVKDYGWVTIIAKPLFWLLQKIHGYVGNWGWSIVLLTVLIKAVFFPLSAASYKSMARMKEITP
RMQQLRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPYFILP
VLMAGSMFLQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRAIGNKKKAT

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=505, Percent_Identity=38.2178217821782, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24662345, Length=191, Percent_Identity=25.6544502617801, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356443, Length=191, Percent_Identity=25.6544502617801, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 61394; Mature: 61394

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKRTVLWVIFFMSAVMLFDNWQRAHGRQSMFFPNVTQTNVAASKGGADTGASAASGAT
CCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AALPAASTQAPAATTPIAQAQLVPFSTDVYDGEIDTRGGTLTKLTLKKEGDGKQPDLFVT
EECCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCEEEEEEEEECCCCCCCCEEEE
LFDHTKDHTYLARTGVTGGNFPNHNDLFTPLSGPRSLAAGQDTLKLSFESQEKGGVKVVK
EECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCCEEEEEECCCCCCCEEEEE
TYTFTRGSYVIGVDTKIENVGTAPVTPTVYMEIVRDSTPVETPLFSHTFLGPAVYTDQKH
EEEEECCCEEEEECCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCEECCHHH
FQKITFSDIDKNKAEYVTSADNGWVAMVQHYFASAWIPQAGVKRDIYVEKIDPSLYRIGV
HHCCCHHHCCCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEECC
KEPVKTIEPGQSADVSARLFAGPEEERVLEGIAPGLDLVKDYGWVTIIAKPLFWLLQKIH
CCCHHHCCCCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHCCEEEEHHHHHHHHHHHHH
GYVGNWGWSIVLLTVLIKAVFFPLSAASYKSMARMKEITPRMQQLRERFKSDPQKMNAAL
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPYFILP
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEH
VLMAGSMFLQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQY
HHHCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YITRAIGNKKKAT
HHHHHHCCCCCCC
>Mature Secondary Structure
MDIKRTVLWVIFFMSAVMLFDNWQRAHGRQSMFFPNVTQTNVAASKGGADTGASAASGAT
CCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AALPAASTQAPAATTPIAQAQLVPFSTDVYDGEIDTRGGTLTKLTLKKEGDGKQPDLFVT
EECCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCEEEEEEEEECCCCCCCCEEEE
LFDHTKDHTYLARTGVTGGNFPNHNDLFTPLSGPRSLAAGQDTLKLSFESQEKGGVKVVK
EECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCCEEEEEECCCCCCCEEEEE
TYTFTRGSYVIGVDTKIENVGTAPVTPTVYMEIVRDSTPVETPLFSHTFLGPAVYTDQKH
EEEEECCCEEEEECCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCEECCHHH
FQKITFSDIDKNKAEYVTSADNGWVAMVQHYFASAWIPQAGVKRDIYVEKIDPSLYRIGV
HHCCCHHHCCCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEECC
KEPVKTIEPGQSADVSARLFAGPEEERVLEGIAPGLDLVKDYGWVTIIAKPLFWLLQKIH
CCCHHHCCCCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHCCEEEEHHHHHHHHHHHHH
GYVGNWGWSIVLLTVLIKAVFFPLSAASYKSMARMKEITPRMQQLRERFKSDPQKMNAAL
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPYFILP
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEH
VLMAGSMFLQTRLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQY
HHHCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YITRAIGNKKKAT
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA