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The map label for this gene is dppA [H]

Identifier: 238028870

GI number: 238028870

Start: 3793377

End: 3794993

Strand: Reverse

Name: dppA [H]

Synonym: bglu_1g33350

Alternate gene names: 238028870

Gene position: 3794993-3793377 (Counterclockwise)

Preceding gene: 238028871

Following gene: 238028869

Centisome position: 97.15

GC content: 65.49

Gene sequence:

>1617_bases
ATGACATCAGATCGTCTGTTGCGCGCGGCCCTGGCCGCCGTCGCGGCGGCCGCGTTCGGCATCTCGGGTGCCGCGCATGC
GCAGATCCCGAACAAGACGCTCGTCTACTGCTCGGAAGGCAGCCCGGCGGGCTTCGATTCGGCGCAGTACACGACCGGCA
CGGATTTCTCGGCGGCCACCTTCACCATCTACAACCGCCTCGTCGAGTTCGTGCGCGGCGGCACCAAGGTCGAGCCGGGC
CTGGCCGAGTCGTGGGACATCTCGCCGGACGGCAAGGTCTACACGTTCCACCTGCGCCATGGCGTGAAGTTCCAGACCAC
CGACTACTTCAAGCCCACGCGCGAGTTCAACGCCGACGACGTGCTGTTTACGTTCGAGCGCATGCTCGATCCCAACCAGC
CGTTCCGCAAGGCCTATCCGGTGAGCTTCCCGTACTTCACCGACATGGGCCTCGACAAGCTGATCACGAAGGTGGAGAAG
GTCGATCCGTACACGGTGCGCTTCACGCTCAGCGAGCCGAACGCGCCGTTCATCCAGAACATGGCGATGGAATTCGCCTC
GATCCTGTCGGCCGAATACGCCGACCAGCTGCTCAAGGCCGGCCACGCCGCCGACATCAACCAGAAGCCGATCGGCACCG
GGCCGTTCATCCTGCGCAGCTACACCAAGGACGCGACGATCCGCTACGACGGCAACCCCGATTACTGGAAGAAGGGCGCG
GTGAAGATCGCGAAGCTGATCTTCTCGATCACGCCCGACGCCGGCGTGCGCGTGCAGAAGATGAAGCGCAACGAGTGCCA
GGTGATGAGCTATCCGCGCCCGGCCGACATCGCCACGCTGAAGGCCGACCCGAACCTGGACATGCCCTCGCAGGCGGGCT
TCAACCTCGGCTACCTCGCCTACAACACCCAGCACAAGCCGCTCAATAAGCTCGAGGTGCGCCGCGCGCTCGACATGGCG
ATCAACAAGAAGGCGATCCTCGAATCGGTCTACCAGGGCGCCGGCCAGGCGGCCGCCGCGCCGATGCCGCCGACCCAGTG
GTCGTTCGACCCGAACCTGAAGTCGGCCCCCTACGATCCGGCGGCGGCCAAGGCGCTGCTCGCCAAGGCGGGCTTCCCGA
ACGGCTTCTCGATCTCGCTCTGGGCGATGCCGGTGCAGCGCGCCTACAACCCCAACGCGAAGCTGATGGCCGAGATGATC
CAGGCCGACTGGGCCAAGCTCGGCGTGAAGGCGAACATCGTCAGCTATGAGTGGGGCGAGTACATCAAGCGCGCTCACGC
GGGCGAGCAGGACGCGATGCTGATCGGCTGGACCGGCGACAACGGCGACCCCGACAACTGGCTCGCCACCCAGCTCGGCT
GCGAGGCGATCGGCGGCAACAACTTCACGCGCTGGTGCGACAAGTCGTTTGACGCGCTCGTGAAGAAGGGCCGCGAGACC
ACCGGCCAGGACGCGCGCACCAAGATCTACACGCAGGCGCAGCAGATCTACGCGCAGCAGCTGCCGTACACGGCGATCGC
GAACTCCACCGTCTACCAGCCGGTGCGCAAGACCGTGGTCGACCAGCGGATCGAGCCGCTCGGCTTCATCCGCTTCGACG
GCGTCAGCGTAAAGTAA

Upstream 100 bases:

>100_bases
GCCTTGCGCGCCAGGGCCGGCCAGCCTTGTTCGTCCTGCGAAAGCTCAAGTAAGATCGCCGCACGCCGGCACGGCCGGCA
CGAGACCTGGAGAAAACACA

Downstream 100 bases:

>100_bases
GCGGCCGCCGTTCGCGCACCGTTGCACCGACTGCACGATAATTGATCCGGCGACGGGGGGCTTGGCCCCTCGTCGCCGGA
CGCACTTCACCCCCACGATT

Product: oligopeptide ABC transporter periplasmic ligand binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MTSDRLLRAALAAVAAAAFGISGAAHAQIPNKTLVYCSEGSPAGFDSAQYTTGTDFSAATFTIYNRLVEFVRGGTKVEPG
LAESWDISPDGKVYTFHLRHGVKFQTTDYFKPTREFNADDVLFTFERMLDPNQPFRKAYPVSFPYFTDMGLDKLITKVEK
VDPYTVRFTLSEPNAPFIQNMAMEFASILSAEYADQLLKAGHAADINQKPIGTGPFILRSYTKDATIRYDGNPDYWKKGA
VKIAKLIFSITPDAGVRVQKMKRNECQVMSYPRPADIATLKADPNLDMPSQAGFNLGYLAYNTQHKPLNKLEVRRALDMA
INKKAILESVYQGAGQAAAAPMPPTQWSFDPNLKSAPYDPAAAKALLAKAGFPNGFSISLWAMPVQRAYNPNAKLMAEMI
QADWAKLGVKANIVSYEWGEYIKRAHAGEQDAMLIGWTGDNGDPDNWLATQLGCEAIGGNNFTRWCDKSFDALVKKGRET
TGQDARTKIYTQAQQIYAQQLPYTAIANSTVYQPVRKTVVDQRIEPLGFIRFDGVSVK

Sequences:

>Translated_538_residues
MTSDRLLRAALAAVAAAAFGISGAAHAQIPNKTLVYCSEGSPAGFDSAQYTTGTDFSAATFTIYNRLVEFVRGGTKVEPG
LAESWDISPDGKVYTFHLRHGVKFQTTDYFKPTREFNADDVLFTFERMLDPNQPFRKAYPVSFPYFTDMGLDKLITKVEK
VDPYTVRFTLSEPNAPFIQNMAMEFASILSAEYADQLLKAGHAADINQKPIGTGPFILRSYTKDATIRYDGNPDYWKKGA
VKIAKLIFSITPDAGVRVQKMKRNECQVMSYPRPADIATLKADPNLDMPSQAGFNLGYLAYNTQHKPLNKLEVRRALDMA
INKKAILESVYQGAGQAAAAPMPPTQWSFDPNLKSAPYDPAAAKALLAKAGFPNGFSISLWAMPVQRAYNPNAKLMAEMI
QADWAKLGVKANIVSYEWGEYIKRAHAGEQDAMLIGWTGDNGDPDNWLATQLGCEAIGGNNFTRWCDKSFDALVKKGRET
TGQDARTKIYTQAQQIYAQQLPYTAIANSTVYQPVRKTVVDQRIEPLGFIRFDGVSVK
>Mature_537_residues
TSDRLLRAALAAVAAAAFGISGAAHAQIPNKTLVYCSEGSPAGFDSAQYTTGTDFSAATFTIYNRLVEFVRGGTKVEPGL
AESWDISPDGKVYTFHLRHGVKFQTTDYFKPTREFNADDVLFTFERMLDPNQPFRKAYPVSFPYFTDMGLDKLITKVEKV
DPYTVRFTLSEPNAPFIQNMAMEFASILSAEYADQLLKAGHAADINQKPIGTGPFILRSYTKDATIRYDGNPDYWKKGAV
KIAKLIFSITPDAGVRVQKMKRNECQVMSYPRPADIATLKADPNLDMPSQAGFNLGYLAYNTQHKPLNKLEVRRALDMAI
NKKAILESVYQGAGQAAAAPMPPTQWSFDPNLKSAPYDPAAAKALLAKAGFPNGFSISLWAMPVQRAYNPNAKLMAEMIQ
ADWAKLGVKANIVSYEWGEYIKRAHAGEQDAMLIGWTGDNGDPDNWLATQLGCEAIGGNNFTRWCDKSFDALVKKGRETT
GQDARTKIYTQAQQIYAQQLPYTAIANSTVYQPVRKTVVDQRIEPLGFIRFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=536, Percent_Identity=51.865671641791, Blast_Score=577, Evalue=1e-165,
Organism=Escherichia coli, GI1787551, Length=538, Percent_Identity=34.5724907063197, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1787052, Length=436, Percent_Identity=26.8348623853211, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787762, Length=513, Percent_Identity=27.0955165692008, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1789887, Length=533, Percent_Identity=27.3921200750469, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787495, Length=441, Percent_Identity=24.0362811791383, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789397, Length=506, Percent_Identity=23.1225296442688, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081878, Length=533, Percent_Identity=24.202626641651, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59519; Mature: 59388

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDRLLRAALAAVAAAAFGISGAAHAQIPNKTLVYCSEGSPAGFDSAQYTTGTDFSAAT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
FTIYNRLVEFVRGGTKVEPGLAESWDISPDGKVYTFHLRHGVKFQTTDYFKPTREFNADD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCH
VLFTFERMLDPNQPFRKAYPVSFPYFTDMGLDKLITKVEKVDPYTVRFTLSEPNAPFIQN
HHHHHHHHCCCCCCHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
MAMEFASILSAEYADQLLKAGHAADINQKPIGTGPFILRSYTKDATIRYDGNPDYWKKGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEECCCCCEEEECCCCCHHHHHH
VKIAKLIFSITPDAGVRVQKMKRNECQVMSYPRPADIATLKADPNLDMPSQAGFNLGYLA
HHHHHHHHHCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEE
YNTQHKPLNKLEVRRALDMAINKKAILESVYQGAGQAAAAPMPPTQWSFDPNLKSAPYDP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AAAKALLAKAGFPNGFSISLWAMPVQRAYNPNAKLMAEMIQADWAKLGVKANIVSYEWGE
HHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHH
YIKRAHAGEQDAMLIGWTGDNGDPDNWLATQLGCEAIGGNNFTRWCDKSFDALVKKGRET
HHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCC
TGQDARTKIYTQAQQIYAQQLPYTAIANSTVYQPVRKTVVDQRIEPLGFIRFDGVSVK
CCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TSDRLLRAALAAVAAAAFGISGAAHAQIPNKTLVYCSEGSPAGFDSAQYTTGTDFSAAT
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHH
FTIYNRLVEFVRGGTKVEPGLAESWDISPDGKVYTFHLRHGVKFQTTDYFKPTREFNADD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCH
VLFTFERMLDPNQPFRKAYPVSFPYFTDMGLDKLITKVEKVDPYTVRFTLSEPNAPFIQN
HHHHHHHHCCCCCCHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
MAMEFASILSAEYADQLLKAGHAADINQKPIGTGPFILRSYTKDATIRYDGNPDYWKKGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEECCCCCEEEECCCCCHHHHHH
VKIAKLIFSITPDAGVRVQKMKRNECQVMSYPRPADIATLKADPNLDMPSQAGFNLGYLA
HHHHHHHHHCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEE
YNTQHKPLNKLEVRRALDMAINKKAILESVYQGAGQAAAAPMPPTQWSFDPNLKSAPYDP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AAAKALLAKAGFPNGFSISLWAMPVQRAYNPNAKLMAEMIQADWAKLGVKANIVSYEWGE
HHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHH
YIKRAHAGEQDAMLIGWTGDNGDPDNWLATQLGCEAIGGNNFTRWCDKSFDALVKKGRET
HHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCC
TGQDARTKIYTQAQQIYAQQLPYTAIANSTVYQPVRKTVVDQRIEPLGFIRFDGVSVK
CCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]