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The map label for this gene is czcR [H]

Identifier: 238028831

GI number: 238028831

Start: 3752987

End: 3753670

Strand: Reverse

Name: czcR [H]

Synonym: bglu_1g32960

Alternate gene names: 238028831

Gene position: 3753670-3752987 (Counterclockwise)

Preceding gene: 238028832

Following gene: 238028828

Centisome position: 96.09

GC content: 74.71

Gene sequence:

>684_bases
ATGCGCATCCTGCTCGTCGGCTCGCGCCATCCCGAGGCGTCGTGGCTGCACAAGGCGCTGCAGGAGAGCGGCCACAGCCT
GCAGCGCGCCGACGACCTGCGCGACGGGCTGTTCCTCGCCTCGCAGGAGCGCTTCGACGCGATCGTCGCGACCGCGCTCG
ACGCGGGCAGCGACGCGGCGCTGGTGGCCGCGCTGCCGCGCTTCGCGGCCGACGGCGGGGGCGCGGCGCTGGTGGTGCTG
CTCGGCCAGGCGCGGGCCAGCGAGCGCATCCGCGCGCTGCGCGCCGGGGCCGACGCCTGTTTCGGCGCGCCGTACTCGTT
CATCGAGCTGCACGAGCGCCTGCAGGCGCTGCAGCGGCTCGGCACCGGGCGCGAGCCGGACCGGCCGCTCGCCGCGCCGG
CGGGCCTCGAGGCGCTCTCGCGGGAGCTGCAGGACGGCAAGCTGCGGCTGGCCGTGACGCGCCGCGAGTTCCTGCTGCTC
GAATGCCTGATGCGCAGCCCGAACGCGCCGGTGCCGCGCGATCAGCTGATCCGCTACGTGTGGCAGGACAAGGAGGATGT
CGATCCGTCGAGCGTCAACCTGGTGGTGTCGCGGCTGCGCCGCAAGCTCGCGCGGCACCAGCCCGACGTGCGGATCGACA
CGGTGAGCCGCTACGGCTATCAGGTGACGCTGGCGCCGCCCTGA

Upstream 100 bases:

>100_bases
GCCGCGCCCGGCACGCGCGTGACGATCGAGTGCTGGCCGAGGACGCTGGTATGAGCGCGGCCGCCGATACCGGCACGCAC
CGGGCGCAGGGCCGCTGACC

Downstream 100 bases:

>100_bases
GCGCGGCCGGCCAAGGCGCGCCGGGGCGGCAGACGGCGGCAGACGGCGGGCGGCAAGCCACGCGCGCGCCGGCGCGGATG
CGCACGGCGCCCGCGGGCAT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRILLVGSRHPEASWLHKALQESGHSLQRADDLRDGLFLASQERFDAIVATALDAGSDAALVAALPRFAADGGGAALVVL
LGQARASERIRALRAGADACFGAPYSFIELHERLQALQRLGTGREPDRPLAAPAGLEALSRELQDGKLRLAVTRREFLLL
ECLMRSPNAPVPRDQLIRYVWQDKEDVDPSSVNLVVSRLRRKLARHQPDVRIDTVSRYGYQVTLAPP

Sequences:

>Translated_227_residues
MRILLVGSRHPEASWLHKALQESGHSLQRADDLRDGLFLASQERFDAIVATALDAGSDAALVAALPRFAADGGGAALVVL
LGQARASERIRALRAGADACFGAPYSFIELHERLQALQRLGTGREPDRPLAAPAGLEALSRELQDGKLRLAVTRREFLLL
ECLMRSPNAPVPRDQLIRYVWQDKEDVDPSSVNLVVSRLRRKLARHQPDVRIDTVSRYGYQVTLAPP
>Mature_227_residues
MRILLVGSRHPEASWLHKALQESGHSLQRADDLRDGLFLASQERFDAIVATALDAGSDAALVAALPRFAADGGGAALVVL
LGQARASERIRALRAGADACFGAPYSFIELHERLQALQRLGTGREPDRPLAAPAGLEALSRELQDGKLRLAVTRREFLLL
ECLMRSPNAPVPRDQLIRYVWQDKEDVDPSSVNLVVSRLRRKLARHQPDVRIDTVSRYGYQVTLAPP

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=25.9090909090909, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=27.3542600896861, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=25.3393665158371, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24970; Mature: 24970

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVGSRHPEASWLHKALQESGHSLQRADDLRDGLFLASQERFDAIVATALDAGSDAA
CEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LVAALPRFAADGGGAALVVLLGQARASERIRALRAGADACFGAPYSFIELHERLQALQRL
HHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHH
GTGREPDRPLAAPAGLEALSRELQDGKLRLAVTRREFLLLECLMRSPNAPVPRDQLIRYV
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHH
WQDKEDVDPSSVNLVVSRLRRKLARHQPDVRIDTVSRYGYQVTLAPP
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCEEEEECCC
>Mature Secondary Structure
MRILLVGSRHPEASWLHKALQESGHSLQRADDLRDGLFLASQERFDAIVATALDAGSDAA
CEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LVAALPRFAADGGGAALVVLLGQARASERIRALRAGADACFGAPYSFIELHERLQALQRL
HHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHH
GTGREPDRPLAAPAGLEALSRELQDGKLRLAVTRREFLLLECLMRSPNAPVPRDQLIRYV
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHH
WQDKEDVDPSSVNLVVSRLRRKLARHQPDVRIDTVSRYGYQVTLAPP
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]