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The map label for this gene is argG [H]

Identifier: 238028820

GI number: 238028820

Start: 3737535

End: 3738875

Strand: Reverse

Name: argG [H]

Synonym: bglu_1g32850

Alternate gene names: 238028820

Gene position: 3738875-3737535 (Counterclockwise)

Preceding gene: 238028827

Following gene: 238028819

Centisome position: 95.71

GC content: 65.92

Gene sequence:

>1341_bases
ATGACCACGATTCTTGAAAGTCTTCCGACCGGCCAGAAGGTCGGCATCGCGTTCTCCGGCGGGCTCGACACGAGCGCCGC
GCTGCACTGGATGCGGATCAAGGGCGCCGTGCCGTATGCCTACACGGCCAACCTGGGCCAGCCCGACGAATCCGACTACG
ACTCGATCCCGCAGCGCGCGCGCGAATACGGCGCCGAGAACGCGCGCCTGATCGACTGCCGCGCGCAGCTCGTCGCCGAA
GGCATCGCCGCGCTGCAATCGGGCGCGTTCCACATCTCGACGGCCGGCGTCACTTATTTCAATACGACCCCGATTGGCCG
TGCCGTGACCGGCACGATGCTGGTGGCGGCGATGAAGGAAGACGGCGTCAACATCTGGGGCGATGGCAGCACCTACAAGG
GCAACGACATCGAGCGCTTCTACCGGTACGGCCTGCTCGTCAATCCGGACCTGAAGATCTACAAGCCGTGGCTCGACCAG
CAGTTCATCGACGAGCTGGGCGGCCGCGCGGAAATGTCCGAATTCATGAGCAAGGCCGGCTTCGGCTACAAGATGTCGGC
CGAGAAGGCCTATTCGACCGATTCGAACCTGCTCGGCGCCACCCACGAGGCGAAGGATCTCGAAAGCCTCGAGAGCGGCA
TCAAGATCGTCAACCCGATCATGGGCGTGGCATTCTGGCGCGATGACGTGAAGATCGCCGCCGAAACCGTCACGGTGCGC
TTCGAGGAAGGCCGTCCGGTGGCGCTCAACGGCGTGGAGTTCAGCGACCAGGTCGAGCTGCTGCTCGAGGCGAACCGGAT
CGGCGGGCGCCACGGCCTGGGCATGAGCGACCAGATCGAGAACCGCATCATCGAGGCCAAGAGCCGCGGCATCTACGAGG
CCCCGGGCCTCGCGCTGCTCTACATCGCCTACGAGCGGCTCGTCACCGGCATCCACAACGAGGACACCATCGAGCAGTAC
CGCGAGAGCGGCCGCCGGCTCGGCCGCCTGCTGTACCAAGGCCGCTGGTTCGATCCGCAGGCGATCATGCTGCGCGAGAC
GGCGCAGCGCTGGGTGGCGCGCGCCGTCACGGGCGAGGTCCAGATCGAGCTGCGCCGCGGCAACGACTATTCGATCCTGA
GCACGAAGTCGCCGAACCTGACCTACGCGCCCGAGCGCCTGTCGATGGAGAAGGTCGCCTCGACGTTCTCGCCGCGCGAC
CGGATCGGCCAGCTGACGATGCGCAATCTCGACATCACCGATACGCGCGACAAGCTGCGCGTGTACTCGCAGGTCGGGCT
GCTGACGCCGGGCGAGGCCTCGGCACTGCCGCAGATCCGTCAGGACAAGGACGGCGAGTAA

Upstream 100 bases:

>100_bases
CAAAACTTGGCGCGCAATCCTTGCCTCGCCATCGGGCACCGTCGATACTTACGGGTTGCGTGCATATCCTTCCGACCACG
AAATCACTCGGTTTATCGCC

Downstream 100 bases:

>100_bases
GCCGCCGGCGGCGCGGGCCGCCGGCCGGCCGCGTCTCGCCTCGCCTCGCGCGGTTCTCCGCCGGGGCGGCCGGGGGCGCG
CCGTGCCGCGCCCGCCATTG

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTTILESLPTGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDESDYDSIPQRAREYGAENARLIDCRAQLVAE
GIAALQSGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQ
QFIDELGGRAEMSEFMSKAGFGYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIAAETVTVR
FEEGRPVALNGVEFSDQVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQY
RESGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVQIELRRGNDYSILSTKSPNLTYAPERLSMEKVASTFSPRD
RIGQLTMRNLDITDTRDKLRVYSQVGLLTPGEASALPQIRQDKDGE

Sequences:

>Translated_446_residues
MTTILESLPTGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDESDYDSIPQRAREYGAENARLIDCRAQLVAE
GIAALQSGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQ
QFIDELGGRAEMSEFMSKAGFGYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIAAETVTVR
FEEGRPVALNGVEFSDQVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQY
RESGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVQIELRRGNDYSILSTKSPNLTYAPERLSMEKVASTFSPRD
RIGQLTMRNLDITDTRDKLRVYSQVGLLTPGEASALPQIRQDKDGE
>Mature_445_residues
TTILESLPTGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDESDYDSIPQRAREYGAENARLIDCRAQLVAEG
IAALQSGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQ
FIDELGGRAEMSEFMSKAGFGYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIAAETVTVRF
EEGRPVALNGVEFSDQVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYR
ESGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVQIELRRGNDYSILSTKSPNLTYAPERLSMEKVASTFSPRDR
IGQLTMRNLDITDTRDKLRVYSQVGLLTPGEASALPQIRQDKDGE

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=409, Percent_Identity=29.0953545232274, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI16950633, Length=409, Percent_Identity=29.0953545232274, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1789563, Length=439, Percent_Identity=79.9544419134396, Blast_Score=736, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324514, Length=419, Percent_Identity=29.8329355608592, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21358151, Length=424, Percent_Identity=27.8301886792453, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 49515; Mature: 49383

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILESLPTGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDESDYDSIPQRA
CCCHHHHCCCCCEEEEEEECCCCHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHH
REYGAENARLIDCRAQLVAEGIAALQSGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKE
HHHCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHHHEEHHC
DGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMSKAG
CCCEEECCCCCCCCCHHHHHHHCCCEECCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCC
FGYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIAAETVTVR
CCEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
FEEGRPVALNGVEFSDQVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALL
EECCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHH
YIAYERLVTGIHNEDTIEQYRESGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEE
QIELRRGNDYSILSTKSPNLTYAPERLSMEKVASTFSPRDRIGQLTMRNLDITDTRDKLR
EEEEEECCCEEEEEECCCCCEECHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCHHHHH
VYSQVGLLTPGEASALPQIRQDKDGE
HHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTILESLPTGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDESDYDSIPQRA
CCHHHHCCCCCEEEEEEECCCCHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHH
REYGAENARLIDCRAQLVAEGIAALQSGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKE
HHHCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHHHEEHHC
DGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMSKAG
CCCEEECCCCCCCCCHHHHHHHCCCEECCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCC
FGYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIAAETVTVR
CCEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
FEEGRPVALNGVEFSDQVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALL
EECCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHH
YIAYERLVTGIHNEDTIEQYRESGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEE
QIELRRGNDYSILSTKSPNLTYAPERLSMEKVASTFSPRDRIGQLTMRNLDITDTRDKLR
EEEEEECCCEEEEEECCCCCEECHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCHHHHH
VYSQVGLLTPGEASALPQIRQDKDGE
HHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA