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The map label for this gene is kdsC [H]

Identifier: 238028653

GI number: 238028653

Start: 3546451

End: 3546990

Strand: Direct

Name: kdsC [H]

Synonym: bglu_1g31170

Alternate gene names: 238028653

Gene position: 3546451-3546990 (Clockwise)

Preceding gene: 238028652

Following gene: 238028654

Centisome position: 90.78

GC content: 72.04

Gene sequence:

>540_bases
ATGTCCGCTGCCCCCGCCACGGCCGCCGAACGCGCGAGCCGCGTGAAGCTGATGATTTTCGACGTCGACGGCGTGCTGAC
CGACGGCGGCCTGCATTTCACGGCCGCCGGCGACACCATGAAGTCGTTCCATTCGCAGGACGGCCACGGCCTGAAGCTGC
TGCGCGAAGCCGGCATCGACACGGCGATCATCACCGGGCGCCGCTCGGAGATCGTCGCCATGCGCGCCCGGGAGCTGCGC
ATCAGTCATCTCTACCAGGGCGTCGAGCACAAGCTCGAGGCATTCGCCGAACTGCTGCGGGCCACCGGCGTGCCGCCCGA
GCAATGCGGCTACATGGGCGACGACTGGCCCGACCTGGGCGTGATGACGCGCTGCGGTTTCGTGGCCGCCCCCGCCAACG
CGCATCCGGACGTGATCGCGCGCGCCCACTGGGTGGCCGAGGCGCGCGGCGGCCAGGGCGCCGCGCGCGAGGTGGTCGAC
ACGATCCTGCGCGCGCAGGGCCGCTACGAGGCGCTGCTGGCCGCCGCGCTCGGAGCCTGA

Upstream 100 bases:

>100_bases
TGGAGCGCTACCGGATCAACCAGATGCTGGTGACCGATCCGGACGGTACGCTGATCGGCGCGCTCAACATGCACGACCTG
TTCTCCCAGAAGGTGATCTG

Downstream 100 bases:

>100_bases
CGCATGACGCCCCGGTTTCGCCTGACCTCGCTGCTGCCGGTGATCGCGATGGCCGCGCTCGCCGGCGTGACCTATTGGCT
GCTGCAGGCCACGCTGCCGC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSAAPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDTMKSFHSQDGHGLKLLREAGIDTAIITGRRSEIVAMRARELR
ISHLYQGVEHKLEAFAELLRATGVPPEQCGYMGDDWPDLGVMTRCGFVAAPANAHPDVIARAHWVAEARGGQGAAREVVD
TILRAQGRYEALLAAALGA

Sequences:

>Translated_179_residues
MSAAPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDTMKSFHSQDGHGLKLLREAGIDTAIITGRRSEIVAMRARELR
ISHLYQGVEHKLEAFAELLRATGVPPEQCGYMGDDWPDLGVMTRCGFVAAPANAHPDVIARAHWVAEARGGQGAAREVVD
TILRAQGRYEALLAAALGA
>Mature_178_residues
SAAPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDTMKSFHSQDGHGLKLLREAGIDTAIITGRRSEIVAMRARELRI
SHLYQGVEHKLEAFAELLRATGVPPEQCGYMGDDWPDLGVMTRCGFVAAPANAHPDVIARAHWVAEARGGQGAAREVVDT
ILRAQGRYEALLAAALGA

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI2367202, Length=160, Percent_Identity=43.75, Blast_Score=146, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19074; Mature: 18943

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDTMKSFHSQDGHGLKLLREAGID
CCCCCCHHHHHHCCEEEEEEECCCEEECCCEEEEECCHHHHHHHCCCCCHHHHHHHCCCC
TAIITGRRSEIVAMRARELRISHLYQGVEHKLEAFAELLRATGVPPEQCGYMGDDWPDLG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCH
VMTRCGFVAAPANAHPDVIARAHWVAEARGGQGAAREVVDTILRAQGRYEALLAAALGA
HHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SAAPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDTMKSFHSQDGHGLKLLREAGID
CCCCCHHHHHHCCEEEEEEECCCEEECCCEEEEECCHHHHHHHCCCCCHHHHHHHCCCC
TAIITGRRSEIVAMRARELRISHLYQGVEHKLEAFAELLRATGVPPEQCGYMGDDWPDLG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCH
VMTRCGFVAAPANAHPDVIARAHWVAEARGGQGAAREVVDTILRAQGRYEALLAAALGA
HHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]