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The map label for this gene is pdxA [H]

Identifier: 238028596

GI number: 238028596

Start: 3476578

End: 3477570

Strand: Reverse

Name: pdxA [H]

Synonym: bglu_1g30600

Alternate gene names: 238028596

Gene position: 3477570-3476578 (Counterclockwise)

Preceding gene: 238028597

Following gene: 238028595

Centisome position: 89.02

GC content: 74.42

Gene sequence:

>993_bases
ATGGCCACCGACCCGACGCTGCGCATCGCGATCACCACCGGCGAGCCGGCCGGGGTCGGCCCCGAGCTGAGCGCGCGCGC
GCTTGCCGAGGCGCCGCTGCGCTGGCCCGACGCGTGCTTCGAGGTGCTGTGCGACGCGGCGCTGTTCGCCGAACGCGCGC
AGGCGGCCGGCGTCGATCCGGCCGCGCTCGGCGTCGGCCAGCGCGTGACGGTGGCGCATCGCCCGCTCGCCGCGCCGGCG
CGGGCCGGGCAGCTCGACGCGGCCAACGGCCGCTACGTGCTGGGCCTGCTCGACGCGGCGATCGACGGCGCGGTGGCGGG
CCGCTACGACGCGATCGTCACGGCGCCGCTGCAGAAGAGCACCATCAACGATGCCGGCGTACCGTTCACCGGCCATACCG
AATATCTGGCCGAGCGCACCGGCACGCCGCGCGTCGTGATGATGCTGGCCGGCACCGGCGAGCGGCCGCTGCGCGTCGCA
CTCGCCACCACGCACCTGCCGCTCAAGGACGTGTCGGCCGCGCTGACGATCGACTCGCTGGTCGAGACGCTCGCCATCGT
CGACGCCGACCTGCGCCGCCATTTCGGCCTGGCCGCCCCGCGCATCCTCGTCACCGGCCTGAACCCGCACGCGGGCGAGA
ACGGCTACCTCGGCCGCGAGGAGATCGACGTGATCGCGCCGGCGCTGGCCGAGGCCAAGGCGCGCGGCATCGACGCGCGC
GGCCCGTATCCGGCCGACACGCTGTTCCAGCCGCGCTACCTCGAGCACGCCGACTGCGTGCTCGCGATGTTCCATGACCA
GGGCCTGCCGGTGCTCAAGTTCGCGACGTTCGGCGAAGGCATCAATGTCACGCTCGGCCTGCCGATCGTGCGCACCTCGG
TCGACCATGGCACCGCGCTCGATCTGGCCGGCACCGGCCGCGCCGATCCGGGCAGCCTGATCGCCGCGCTCGACACCGCG
GTCGCGATGGCGCGCCACCGCCGCGGTGCCTGA

Upstream 100 bases:

>100_bases
GCAAGGCCGAGCAGGCCTATGCCGACTGGCTGCGCGAGCTGCGCGATTCGTCCTACGTGCAGATCAAGATCGGCCAGCCG
CAGCCCTGAGCGAGCCCGCC

Downstream 100 bases:

>100_bases
GGCACCGCTCGCTCCACTTTCGTTTGATTCTTTCGATGTCGAACAGCAGACAGCACCAGGGACACTTCGCGCGCAAGCGC
TTCGGGCAGAACTTTCTCGT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MATDPTLRIAITTGEPAGVGPELSARALAEAPLRWPDACFEVLCDAALFAERAQAAGVDPAALGVGQRVTVAHRPLAAPA
RAGQLDAANGRYVLGLLDAAIDGAVAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTGTPRVVMMLAGTGERPLRVA
LATTHLPLKDVSAALTIDSLVETLAIVDADLRRHFGLAAPRILVTGLNPHAGENGYLGREEIDVIAPALAEAKARGIDAR
GPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKFATFGEGINVTLGLPIVRTSVDHGTALDLAGTGRADPGSLIAALDTA
VAMARHRRGA

Sequences:

>Translated_330_residues
MATDPTLRIAITTGEPAGVGPELSARALAEAPLRWPDACFEVLCDAALFAERAQAAGVDPAALGVGQRVTVAHRPLAAPA
RAGQLDAANGRYVLGLLDAAIDGAVAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTGTPRVVMMLAGTGERPLRVA
LATTHLPLKDVSAALTIDSLVETLAIVDADLRRHFGLAAPRILVTGLNPHAGENGYLGREEIDVIAPALAEAKARGIDAR
GPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKFATFGEGINVTLGLPIVRTSVDHGTALDLAGTGRADPGSLIAALDTA
VAMARHRRGA
>Mature_329_residues
ATDPTLRIAITTGEPAGVGPELSARALAEAPLRWPDACFEVLCDAALFAERAQAAGVDPAALGVGQRVTVAHRPLAAPAR
AGQLDAANGRYVLGLLDAAIDGAVAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTGTPRVVMMLAGTGERPLRVAL
ATTHLPLKDVSAALTIDSLVETLAIVDADLRRHFGLAAPRILVTGLNPHAGENGYLGREEIDVIAPALAEAKARGIDARG
PYPADTLFQPRYLEHADCVLAMFHDQGLPVLKFATFGEGINVTLGLPIVRTSVDHGTALDLAGTGRADPGSLIAALDTAV
AMARHRRGA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=329, Percent_Identity=53.1914893617021, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34339; Mature: 34207

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDPTLRIAITTGEPAGVGPELSARALAEAPLRWPDACFEVLCDAALFAERAQAAGVDP
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
AALGVGQRVTVAHRPLAAPARAGQLDAANGRYVLGLLDAAIDGAVAGRYDAIVTAPLQKS
HHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHCCCCCEEEECCCCCC
TINDAGVPFTGHTEYLAERTGTPRVVMMLAGTGERPLRVALATTHLPLKDVSAALTIDSL
CCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHH
VETLAIVDADLRRHFGLAAPRILVTGLNPHAGENGYLGREEIDVIAPALAEAKARGIDAR
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKFATFGEGINVTLGLPIVRTSVDHGTAL
CCCCCCCCCCCCHHCHHHEEEEEECCCCCCEEEEEECCCCEEEEECCCEEEECCCCCCEE
DLAGTGRADPGSLIAALDTAVAMARHRRGA
EECCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATDPTLRIAITTGEPAGVGPELSARALAEAPLRWPDACFEVLCDAALFAERAQAAGVDP
CCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
AALGVGQRVTVAHRPLAAPARAGQLDAANGRYVLGLLDAAIDGAVAGRYDAIVTAPLQKS
HHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHCCCCCEEEECCCCCC
TINDAGVPFTGHTEYLAERTGTPRVVMMLAGTGERPLRVALATTHLPLKDVSAALTIDSL
CCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHH
VETLAIVDADLRRHFGLAAPRILVTGLNPHAGENGYLGREEIDVIAPALAEAKARGIDAR
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKFATFGEGINVTLGLPIVRTSVDHGTAL
CCCCCCCCCCCCHHCHHHEEEEEECCCCCCEEEEEECCCCEEEEECCCEEEECCCCCCEE
DLAGTGRADPGSLIAALDTAVAMARHRRGA
EECCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA