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The map label for this gene is rsmA [H]

Identifier: 238028595

GI number: 238028595

Start: 3475712

End: 3476542

Strand: Reverse

Name: rsmA [H]

Synonym: bglu_1g30590

Alternate gene names: 238028595

Gene position: 3476542-3475712 (Counterclockwise)

Preceding gene: 238028596

Following gene: 238028594

Centisome position: 88.99

GC content: 69.43

Gene sequence:

>831_bases
ATGTCGAACAGCAGACAGCACCAGGGACACTTCGCGCGCAAGCGCTTCGGGCAGAACTTTCTCGTCGACACCGGCGTGAT
CGACTCGATCGTCTCGACGATCCGCCCCGAGCGCGGCCAGCGCATGGTCGAGATCGGCCCCGGCCTCGGCGCGCTGACCG
GCCCCGTGATCGAGCGGCTCGCCACGCCGGAGGCGCCGCTGCACGCCGTCGAGCTCGACCGCGACCTGATCGGCCGCCTC
AAGCAGCGCTTCGGCAGCCTGCTGGAGCTGCATGCCGGCGACGCGCTCGGGTTCGATTTCGGCGCGCTCGCGCTGCCGGG
CGAGCAGCCGTCGCTGCGCATCATCGGCAATCTGCCCTACAACATCTCCAGCCCGCTGCTGTTCCACCTGATGAGGTTCG
CCGAACGCGTGGTGGACCAGCACTTCATGCTGCAGAACGAGGTGGTCGAGCGGATGGTGGCCGAGCCGGGCAGCAAGGCG
TTCAGCCGGCTGTCGGTGATGCTGCAGTACCGCTACGTGATGGACAAGCTGATCGACGTGCCGCCCGAGTCGTTCCAGCC
GCCGCCGAAGGTCGATTCGGCGATCGTGCGGATGATTCCGCATGCGCCGCACGAGCTGGCCGAGGTGGATGTCGGCGTGC
TCGGCGAGGTGGTCACGGCGGCCTTCTCGCAGCGCCGCAAGATGCTGCGCAACACGCTCGGCGCGTACCGCGACGTGGTC
GATTTCGAGGCGCTCGGCTTCGATCTGGCGCGCCGCGCCGAGGACGTCGGCGTGGCCGAATACGTGAGGCTGGCGCGCAC
GGTCGCCGCGACGCGGCCCGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
CGGGCAGCCTGATCGCCGCGCTCGACACCGCGGTCGCGATGGCGCGCCACCGCCGCGGTGCCTGAGGCACCGCTCGCTCC
ACTTTCGTTTGATTCTTTCG

Downstream 100 bases:

>100_bases
GGCGGGCGGCGGCGCGGGCCGTCATGCCCGCGGTCCGGATCGGCCGGCCGGGCCGGTTCGCGGATGCGCCGGCCCGCCGG
CGAAAATCGGCCGCGTCTGG

Product: 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSNSRQHQGHFARKRFGQNFLVDTGVIDSIVSTIRPERGQRMVEIGPGLGALTGPVIERLATPEAPLHAVELDRDLIGRL
KQRFGSLLELHAGDALGFDFGALALPGEQPSLRIIGNLPYNISSPLLFHLMRFAERVVDQHFMLQNEVVERMVAEPGSKA
FSRLSVMLQYRYVMDKLIDVPPESFQPPPKVDSAIVRMIPHAPHELAEVDVGVLGEVVTAAFSQRRKMLRNTLGAYRDVV
DFEALGFDLARRAEDVGVAEYVRLARTVAATRPAAG

Sequences:

>Translated_276_residues
MSNSRQHQGHFARKRFGQNFLVDTGVIDSIVSTIRPERGQRMVEIGPGLGALTGPVIERLATPEAPLHAVELDRDLIGRL
KQRFGSLLELHAGDALGFDFGALALPGEQPSLRIIGNLPYNISSPLLFHLMRFAERVVDQHFMLQNEVVERMVAEPGSKA
FSRLSVMLQYRYVMDKLIDVPPESFQPPPKVDSAIVRMIPHAPHELAEVDVGVLGEVVTAAFSQRRKMLRNTLGAYRDVV
DFEALGFDLARRAEDVGVAEYVRLARTVAATRPAAG
>Mature_275_residues
SNSRQHQGHFARKRFGQNFLVDTGVIDSIVSTIRPERGQRMVEIGPGLGALTGPVIERLATPEAPLHAVELDRDLIGRLK
QRFGSLLELHAGDALGFDFGALALPGEQPSLRIIGNLPYNISSPLLFHLMRFAERVVDQHFMLQNEVVERMVAEPGSKAF
SRLSVMLQYRYVMDKLIDVPPESFQPPPKVDSAIVRMIPHAPHELAEVDVGVLGEVVTAAFSQRRKMLRNTLGAYRDVVD
FEALGFDLARRAEDVGVAEYVRLARTVAATRPAAG

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Homo sapiens, GI7657198, Length=194, Percent_Identity=33.5051546391753, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI156415992, Length=241, Percent_Identity=32.3651452282158, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786236, Length=275, Percent_Identity=54.1818181818182, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI25146882, Length=198, Percent_Identity=34.8484848484849, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25141369, Length=277, Percent_Identity=28.158844765343, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324989, Length=183, Percent_Identity=33.879781420765, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21358017, Length=206, Percent_Identity=33.9805825242718, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357273, Length=299, Percent_Identity=29.4314381270903, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 30527; Mature: 30395

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSRQHQGHFARKRFGQNFLVDTGVIDSIVSTIRPERGQRMVEIGPGLGALTGPVIERL
CCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
ATPEAPLHAVELDRDLIGRLKQRFGSLLELHAGDALGFDFGALALPGEQPSLRIIGNLPY
CCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCCC
NISSPLLFHLMRFAERVVDQHFMLQNEVVERMVAEPGSKAFSRLSVMLQYRYVMDKLIDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
PPESFQPPPKVDSAIVRMIPHAPHELAEVDVGVLGEVVTAAFSQRRKMLRNTLGAYRDVV
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFEALGFDLARRAEDVGVAEYVRLARTVAATRPAAG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNSRQHQGHFARKRFGQNFLVDTGVIDSIVSTIRPERGQRMVEIGPGLGALTGPVIERL
CCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
ATPEAPLHAVELDRDLIGRLKQRFGSLLELHAGDALGFDFGALALPGEQPSLRIIGNLPY
CCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCCC
NISSPLLFHLMRFAERVVDQHFMLQNEVVERMVAEPGSKAFSRLSVMLQYRYVMDKLIDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
PPESFQPPPKVDSAIVRMIPHAPHELAEVDVGVLGEVVTAAFSQRRKMLRNTLGAYRDVV
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFEALGFDLARRAEDVGVAEYVRLARTVAATRPAAG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA