BacMap

Definition	Burkholderia glumae BGR1 chromosome chromosome 1, complete sequence.
Accession	NC_012724
Length	3,906,507

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The map label for this gene is polS [H]

Identifier: 238028488

GI number: 238028488

Start: 3341394

End: 3342170

Strand: Reverse

Name: polS [H]

Synonym: bglu_1g29520

Alternate gene names: 238028488

Gene position: 3342170-3341394 (Counterclockwise)

Preceding gene: 238028493

Following gene: 238028487

Centisome position: 85.55

GC content: 69.76

Gene sequence:

>777_bases
GTGAGATTGCAGGACAAGGTCGCGATCCTGACGGGCGCCGCCAGCGGCATCGGCGAAGCGGTCGCGCAGCGATATCTGGA
AGAGGGCGCGCGCTGCGTGCTGGTCGATCTGAAGCCGGCGGGCGGCTCGCTGGCGGCGTTGATCGCCGAGCACCCCGAGC
GCGCGATCGCGCTCACCGCGGACGTGACGCGGCGCGAGGACATCGCGCGCATCGTCGCCACGGCGGTCGAGCGCTTCGGC
GGCATCGACATCCTGTTCAACAACGCGGCGCTGTTCGACATGCGCCCGCTGCTCGACGAATCCTGGGACATCTTCGACCG
CCTGTTCTCGGTCAACGTGAAGGGCATGTTCTTCCTGATGCAGGCGGTCGCGCAGCGGATGGTCGAGCAGGGCCGCGGCG
GCAAGATCGTCAACATGTCGTCGCAGGCCGGCCGGCGCGGCGAGGCGCTGGTCTCGCACTACTGCGCGACCAAGGCCGCC
GTGCTCAGCTACACGCAATCGGCCGCGCTGGCGCTCGCGCCGCACCGGATCAACGTCAACGGCATCGCGCCGGGCGTGGT
GGACACGCCGATGTGGGAGCAGGTGGATGCCCTGTTCGCGCGCTACGAGAACCGTCCGCTCGGCGAGAAGAAGCGCCTGG
TGGGCGAGGCGGTGCCGCTCGGCCGCATGGGCCTGCCCGCCGACCTGACGGGCGCCGCGCTGTTCCTTGCCTCGGCCGAC
GCCGACTACATCACCGCCCAGACGCTCAATGTCGACGGCGGCAACTGGATGAGCTGA

Upstream 100 bases:

>100_bases
GTATCCGATTATTCGATCGCAATCTGAGCAAATGATCGTTTAATGAGCGTTAGCTCAGTCAATACCGGATCACAGACGGA
TAACGAATCGGAGACAGCCA

Downstream 100 bases:

>100_bases
CGCCATGGCCGAGCTCGTCGTCGCGGGCGAACTGCTCGCCGAATTCGTCGCCGCGCAGCGCGGCCAGGGCTTCGCCGCGC
CGGGCGAATTCAGCGGCCCG

Product: sorbitol dehydrogenase

Products: NA

Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRLQDKVAILTGAASGIGEAVAQRYLEEGARCVLVDLKPAGGSLAALIAEHPERAIALTADVTRREDIARIVATAVERFG
GIDILFNNAALFDMRPLLDESWDIFDRLFSVNVKGMFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA
VLSYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLASAD
ADYITAQTLNVDGGNWMS

Sequences:

>Translated_258_residues
MRLQDKVAILTGAASGIGEAVAQRYLEEGARCVLVDLKPAGGSLAALIAEHPERAIALTADVTRREDIARIVATAVERFG
GIDILFNNAALFDMRPLLDESWDIFDRLFSVNVKGMFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA
VLSYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLASAD
ADYITAQTLNVDGGNWMS
>Mature_258_residues
MRLQDKVAILTGAASGIGEAVAQRYLEEGARCVLVDLKPAGGSLAALIAEHPERAIALTADVTRREDIARIVATAVERFG
GIDILFNNAALFDMRPLLDESWDIFDRLFSVNVKGMFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA
VLSYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLASAD
ADYITAQTLNVDGGNWMS

Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=33.8289962825279, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=34.6303501945525, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=33.8582677165354, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.8936170212766, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.3846153846154, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=31.0344827586207, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=32.0754716981132, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.5175097276265, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=32.6829268292683, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=28.8973384030418, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=28.8537549407115, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=249, Percent_Identity=32.5301204819277, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=32.295719844358, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=34.020618556701, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=33.5260115606936, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=33.695652173913, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=27.027027027027, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=26.4248704663212, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=29.2929292929293, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=26.3636363636364, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI310128830, Length=200, Percent_Identity=27, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310115468, Length=200, Percent_Identity=27, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=27.1276595744681, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=35.15625, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=35.4961832061069, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=32.6693227091633, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=32.6771653543307, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=31.3725490196078, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787335, Length=262, Percent_Identity=31.2977099236641, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=34.6153846153846, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=29.6577946768061, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=32.4324324324324, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=29.5019157088123, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=28.4046692607004, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=27.3092369477912, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=29.6703296703297, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787526, Length=259, Percent_Identity=26.2548262548263, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=31.640625, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=31.640625, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=32.5670498084291, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=33.5907335907336, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17560220, Length=281, Percent_Identity=28.8256227758007, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=31.2727272727273, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=29.7794117647059, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=31.7647058823529, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=32.1705426356589, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=29.2592592592593, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=29.7794117647059, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=29.1512915129151, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=28.1481481481481, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=279, Percent_Identity=27.9569892473118, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.0442804428044, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=27.1062271062271, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=30.5970149253731, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=276, Percent_Identity=28.9855072463768, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=27.8388278388278, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=31.3725490196078, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=27.7978339350181, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=30.2583025830258, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=28.9377289377289, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=30.2583025830258, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=26.9035532994924, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=29.1457286432161, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=29.8969072164948, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=31.3084112149533, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=27.6264591439689, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=27.3764258555133, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=25.9067357512953, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=29.4416243654822, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=34.6938775510204, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=25.7692307692308, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=35.15625, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=34.7490347490347, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=32.9457364341085, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=32.6923076923077, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=31.0077519379845, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=29.2307692307692, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644337, Length=238, Percent_Identity=30.672268907563, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=27.5132275132275, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364892, Length=203, Percent_Identity=30.0492610837438, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=30.1020408163265, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=28.4263959390863, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665264, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=206, Percent_Identity=27.6699029126214, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665268, Length=223, Percent_Identity=26.457399103139, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=26.6009852216749, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.14 [H]

Molecular weight: Translated: 27701; Mature: 27701

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLQDKVAILTGAASGIGEAVAQRYLEEGARCVLVDLKPAGGSLAALIAEHPERAIALTA
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEE
DVTRREDIARIVATAVERFGGIDILFNNAALFDMRPLLDESWDIFDRLFSVNVKGMFFLM
CCHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCHHHHCCHHHHHHHHHHCCCHHHHHHH
QAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALAPHRINVN
HHHHHHHHHCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEC
GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLASAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCC
ADYITAQTLNVDGGNWMS
CCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MRLQDKVAILTGAASGIGEAVAQRYLEEGARCVLVDLKPAGGSLAALIAEHPERAIALTA
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEE
DVTRREDIARIVATAVERFGGIDILFNNAALFDMRPLLDESWDIFDRLFSVNVKGMFFLM
CCHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCHHHHCCHHHHHHHHHHCCCHHHHHHH
QAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALAPHRINVN
HHHHHHHHHCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEC
GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLASAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCC
ADYITAQTLNVDGGNWMS
CCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7551049 [H]