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The map label for this gene is eamA [H]

Identifier: 238028464

GI number: 238028464

Start: 3316076

End: 3316951

Strand: Reverse

Name: eamA [H]

Synonym: bglu_1g29280

Alternate gene names: 238028464

Gene position: 3316951-3316076 (Counterclockwise)

Preceding gene: 238028467

Following gene: 238028461

Centisome position: 84.91

GC content: 71.92

Gene sequence:

>876_bases
ATGATGGCCATGAAGGACCTGTTGCTCGCGTTGGTGGTGATCGTCGCGTGGGGCGTCAACTTCGTCGTGATCAAGCTGGG
CCTGCACGGCGTGCCGCCGATGCTGCTCGGCGCGCTGCGCTTCGCGCTGGCGGCGCTGCCGGCCGTGTTTTTCGTGCCGC
GGCCGCGCATCCCGCTGCGCATGCTGGTGCTGTACGGCGCGACCATCCTGCTCGCGCAGTTCGTGTTCCTGTTTACCGCG
ATGAACGTCGGCATGCCGGCCGGGGTCGCCTCGCTGGTGCTGCAGGCGCAGGCGTTCTTCACGCTCGGCTTCGCGCGGCT
GTTCCTCGGCGAGCGCGTGCGCGCCTGGAACCTGGCGGGCCTCGCGATCGCCGCGCTCGGGCTCGTGACGATCGCCGCGC
GCAGCGGCGGAGCGATGACGCTGGCCGGCTTCGCGCTGACGCTCTGCGCGGCCGCGTCGTGGGCGCTCGGCAACATCGTC
ACGAAGCGGATCGGCAAGGTGGAGCTGGTGCCGCTGGTGGTGTGGGGCAGCCTGGTGCCGCCGCTGCCGTTCCTTGCGCT
GTCGTTCGCGCTCGAAGGCCCGGCGCGGATCGAGGCCGCGCTCGGCGCGCTGTCGGGCGCGTCGGTGTTCGCGATCGTCT
ACCTCGCGTGGGTCGCCACGCTGGTCGGCTACGCGCTGTGGGGCCGGCTGCTGTCGCGCTATCCGGCCGCGCAGGTCGCG
CCGCTCTCGCTGGTGGTGCCGGTGGTCGGCATTGCCTCCTCGGCGCTGCTGCTCGGCGAACGCATGAGCGGCGCCGAATA
CCTGGGCACCGCGCTGGTGATGGCCGGGCTCGTGGTCAACGTATTCGGCGGGCGGCTCGTGCGGCGCACGGCCTGA

Upstream 100 bases:

>100_bases
TGCGCTCATTGTATCGGGCTCGCGGAAAGCGCGGCGACGGGTTGTCACAGCCGTTACACTGCCGGTTTGGTTCGGTCGGG
ATCACGGAGGGCATGACGCG

Downstream 100 bases:

>100_bases
ACACGGCCCGCGCCGCGCGAGGCCTTTTGCGTTGGACGGCGTGGCGGTGCGGCGAAGGCGTCAGCAAACCGCCGCGGACC
GGCGGCCGGGCTTTAGGCCA

Product: DME family drug/metabolite transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MMAMKDLLLALVVIVAWGVNFVVIKLGLHGVPPMLLGALRFALAALPAVFFVPRPRIPLRMLVLYGATILLAQFVFLFTA
MNVGMPAGVASLVLQAQAFFTLGFARLFLGERVRAWNLAGLAIAALGLVTIAARSGGAMTLAGFALTLCAAASWALGNIV
TKRIGKVELVPLVVWGSLVPPLPFLALSFALEGPARIEAALGALSGASVFAIVYLAWVATLVGYALWGRLLSRYPAAQVA
PLSLVVPVVGIASSALLLGERMSGAEYLGTALVMAGLVVNVFGGRLVRRTA

Sequences:

>Translated_291_residues
MMAMKDLLLALVVIVAWGVNFVVIKLGLHGVPPMLLGALRFALAALPAVFFVPRPRIPLRMLVLYGATILLAQFVFLFTA
MNVGMPAGVASLVLQAQAFFTLGFARLFLGERVRAWNLAGLAIAALGLVTIAARSGGAMTLAGFALTLCAAASWALGNIV
TKRIGKVELVPLVVWGSLVPPLPFLALSFALEGPARIEAALGALSGASVFAIVYLAWVATLVGYALWGRLLSRYPAAQVA
PLSLVVPVVGIASSALLLGERMSGAEYLGTALVMAGLVVNVFGGRLVRRTA
>Mature_291_residues
MMAMKDLLLALVVIVAWGVNFVVIKLGLHGVPPMLLGALRFALAALPAVFFVPRPRIPLRMLVLYGATILLAQFVFLFTA
MNVGMPAGVASLVLQAQAFFTLGFARLFLGERVRAWNLAGLAIAALGLVTIAARSGGAMTLAGFALTLCAAASWALGNIV
TKRIGKVELVPLVVWGSLVPPLPFLALSFALEGPARIEAALGALSGASVFAIVYLAWVATLVGYALWGRLLSRYPAAQVA
PLSLVVPVVGIASSALLLGERMSGAEYLGTALVMAGLVVNVFGGRLVRRTA

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=290, Percent_Identity=52.0689655172414, Blast_Score=274, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 30375; Mature: 30375

Theoretical pI: Translated: 11.77; Mature: 11.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAMKDLLLALVVIVAWGVNFVVIKLGLHGVPPMLLGALRFALAALPAVFFVPRPRIPLR
CCHHHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
MLVLYGATILLAQFVFLFTAMNVGMPAGVASLVLQAQAFFTLGFARLFLGERVRAWNLAG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIAALGLVTIAARSGGAMTLAGFALTLCAAASWALGNIVTKRIGKVELVPLVVWGSLVP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCC
PLPFLALSFALEGPARIEAALGALSGASVFAIVYLAWVATLVGYALWGRLLSRYPAAQVA
CHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHC
PLSLVVPVVGIASSALLLGERMSGAEYLGTALVMAGLVVNVFGGRLVRRTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MMAMKDLLLALVVIVAWGVNFVVIKLGLHGVPPMLLGALRFALAALPAVFFVPRPRIPLR
CCHHHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
MLVLYGATILLAQFVFLFTAMNVGMPAGVASLVLQAQAFFTLGFARLFLGERVRAWNLAG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIAALGLVTIAARSGGAMTLAGFALTLCAAASWALGNIVTKRIGKVELVPLVVWGSLVP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCC
PLPFLALSFALEGPARIEAALGALSGASVFAIVYLAWVATLVGYALWGRLLSRYPAAQVA
CHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHC
PLSLVVPVVGIASSALLLGERMSGAEYLGTALVMAGLVVNVFGGRLVRRTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]