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The map label for this gene is cspA [H]

Identifier: 238028419

GI number: 238028419

Start: 3267881

End: 3268102

Strand: Direct

Name: cspA [H]

Synonym: bglu_1g28830

Alternate gene names: 238028419

Gene position: 3267881-3268102 (Clockwise)

Preceding gene: 238028416

Following gene: 238028426

Centisome position: 83.65

GC content: 53.6

Gene sequence:

>222_bases
GTGACAGGGGAAGTAGGTATGGCAACTGGTATCGTCAAGTGGTTCAATGACGCGAAGGGCTTCGGTTTCATTACGCCCGA
TGAAGGCGGCGAAGATCTGTTTGCACATTTCTCGGCCATCAACATGCAGGGTTTCAAGACCCTGAAAGAAGGCCAGAAAG
TGAGCTTCGAGGTGGTTCAAGGCCCGAAGGGCAAGCAGGCTTCGAACATCCAGGCAGCCTGA

Upstream 100 bases:

>100_bases
GTGTTGACGACGGAGAATGGGCCGAGGTGAGCTTGTGAGGGGGGAACGGCTGCATTTGCCGGTCGTTTAGCTTTTCGAGC
GTGCTCGTGGTAACGACTGA

Downstream 100 bases:

>100_bases
GCGCATTGGATTCTCGATAAAAACCCGGCTCCGAGCCGGGTTTTTTTTCGCCGGCCCCATCGGCGTCGGCCTCTTCGCCG
TTCGGCGGCGGCCATGCTCG

Product: Cold shock transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 72

Protein sequence:

>73_residues
MTGEVGMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMQGFKTLKEGQKVSFEVVQGPKGKQASNIQAA

Sequences:

>Translated_73_residues
MTGEVGMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMQGFKTLKEGQKVSFEVVQGPKGKQASNIQAA
>Mature_72_residues
TGEVGMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMQGFKTLKEGQKVSFEVVQGPKGKQASNIQAA

Specific function: Inhibits DNA Replication At Both Initiation And Elongation Steps, Most Probably By Binding To The Opened, Single- Stranded Regions At Replication Forks. Plays A Regulatory Role In Chromosomal Replication In Nutrient-Depleted Cells. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1787107, Length=64, Percent_Identity=65.625, Blast_Score=92, Evalue=6e-21,
Organism=Escherichia coli, GI1789979, Length=67, Percent_Identity=61.1940298507463, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1786841, Length=63, Percent_Identity=61.9047619047619, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI2367114, Length=62, Percent_Identity=58.0645161290323, Blast_Score=82, Evalue=6e-18,
Organism=Escherichia coli, GI1788126, Length=63, Percent_Identity=61.9047619047619, Blast_Score=80, Evalue=2e-17,
Organism=Escherichia coli, GI1787834, Length=64, Percent_Identity=57.8125, Blast_Score=79, Evalue=6e-17,
Organism=Escherichia coli, GI1787839, Length=62, Percent_Identity=56.4516129032258, Blast_Score=78, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71983217, Length=56, Percent_Identity=51.7857142857143, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71983225, Length=56, Percent_Identity=51.7857142857143, Blast_Score=68, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24658520, Length=72, Percent_Identity=43.0555555555556, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7796; Mature: 7665

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEVGMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMQGFKTLKEGQKVSFEVVQ
CCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCEEEEEEE
GPKGKQASNIQAA
CCCCCCCCCCCCC
>Mature Secondary Structure 
TGEVGMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMQGFKTLKEGQKVSFEVVQ
CCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCEEEEEEE
GPKGKQASNIQAA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA