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The map label for this gene is nadA [H]

Identifier: 238028408

GI number: 238028408

Start: 3253221

End: 3254348

Strand: Reverse

Name: nadA [H]

Synonym: bglu_1g28720

Alternate gene names: 238028408

Gene position: 3254348-3253221 (Counterclockwise)

Preceding gene: 238028409

Following gene: 238028407

Centisome position: 83.31

GC content: 68.71

Gene sequence:

>1128_bases
ATGCAAGCGGCGATCAAACCCGTCGAATACGACCGGCCGGGCGCTACCTGCGGCATCGGGCAGGCGTGGGCGAAGGTGCC
CGACAGCCCGTCGGCGACGGAGCGCGACGTGCTGAAGGCGCGAATCAGGGCGCTGCTGGCGCGCGAGAAGGCCGTGCTCG
TCGCGCACTATTACGTCGATGCGGAACTGCAGGAACTGGCCGACGAGACCGGCGGCTGCGTGGCCGACTCGCTCGAGATG
GCGCGCTTCGGCCGCGATCACGACGCGCAAACGCTGATCGTGGCCGGCGTGCGCTTCATGGGCGAGACGGCCAAGATCCT
GAGCCCGGGCAAGCGCATCCTGATGCCCGATCTCGACGCCACCTGCTCGCTCGATCTCGGTTGCCCGGCCGACGAATTCT
CGGCGTTCTGCGACGCGCATCCGGAGCGCAAGGTGGTGGTCTACGCCAACACCAGTGCCGCCGTGAAGGCGCGCGCGGAC
TGGATGGTCACCTCGTCGATCGGCCTCGAGATCGTCGCCGACCTGCATGCGCGCGGCGAGAAGCTGATCTGGGCGCCGGA
CCGGCACCTGGGCAACTACATCCAGAAGAAGACCGGTGCGGACATGCTGATGTGGCAGGGCTCGTGCCTCGTCCACGACG
AATTCAAGGGCATCGAGCTCGACCTGCTGCGCGCCCAGTATCCCGACGCGAAGGTGCTCGTGCACCCGGAATCGCCCGAG
GGCGTGGTCGCGCTCGCCGACGTGGTCGGCTCGACCACGCAGTTGATCGACGCGGCGGTCAGGCTCGACGCGCAGCGCTT
CATCGTCGCGACCGATCTCGGCATCCTGCACAAGATGCGCCTCGCGGCGCCGGGCAAGACCTTCATCGAGGCGCCCACGG
CCGGCAACAGCGCGACCTGCAAGAGCTGCGCGCATTGCCCGTGGATGGCGATGAACGGCCTCGCGAACCTGGCCGACGTG
CTCGAGCGCGGCCACAACGAGATTTACGTCGATCCGGCGCTCGGCCTGCGTGCGCGCGTGCCGATCGACCGCATGCTCGC
GTTCGCCGCCGAGCACAAGCGGCGCGTGCAGGCCAGCGGCGACCTGCAGCGCGATGCGAGCCTGTTCTCGAACGTGGGGG
CGGCATGA

Upstream 100 bases:

>100_bases
ATTAGAATTTCGGTACGTCACAAACCCCGCGCTGGCGGGGTTTTTTCTTTTGTGCCGCCGGTTTCACGGCGGCCGATCGG
CAGGGCAGAGGAGAAGGAAG

Downstream 100 bases:

>100_bases
CGGCGGTCTCCGCGATCTACGGCGAGATCGTCGCCGAATACGGCGCGGCCTTCGAGGCCGCGATCGCGCGCAATGTCGCC
GATGCGATTGCCGAGGACGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MQAAIKPVEYDRPGATCGIGQAWAKVPDSPSATERDVLKARIRALLAREKAVLVAHYYVDAELQELADETGGCVADSLEM
ARFGRDHDAQTLIVAGVRFMGETAKILSPGKRILMPDLDATCSLDLGCPADEFSAFCDAHPERKVVVYANTSAAVKARAD
WMVTSSIGLEIVADLHARGEKLIWAPDRHLGNYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRAQYPDAKVLVHPESPE
GVVALADVVGSTTQLIDAAVRLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNGLANLADV
LERGHNEIYVDPALGLRARVPIDRMLAFAAEHKRRVQASGDLQRDASLFSNVGAA

Sequences:

>Translated_375_residues
MQAAIKPVEYDRPGATCGIGQAWAKVPDSPSATERDVLKARIRALLAREKAVLVAHYYVDAELQELADETGGCVADSLEM
ARFGRDHDAQTLIVAGVRFMGETAKILSPGKRILMPDLDATCSLDLGCPADEFSAFCDAHPERKVVVYANTSAAVKARAD
WMVTSSIGLEIVADLHARGEKLIWAPDRHLGNYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRAQYPDAKVLVHPESPE
GVVALADVVGSTTQLIDAAVRLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNGLANLADV
LERGHNEIYVDPALGLRARVPIDRMLAFAAEHKRRVQASGDLQRDASLFSNVGAA
>Mature_375_residues
MQAAIKPVEYDRPGATCGIGQAWAKVPDSPSATERDVLKARIRALLAREKAVLVAHYYVDAELQELADETGGCVADSLEM
ARFGRDHDAQTLIVAGVRFMGETAKILSPGKRILMPDLDATCSLDLGCPADEFSAFCDAHPERKVVVYANTSAAVKARAD
WMVTSSIGLEIVADLHARGEKLIWAPDRHLGNYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRAQYPDAKVLVHPESPE
GVVALADVVGSTTQLIDAAVRLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNGLANLADV
LERGHNEIYVDPALGLRARVPIDRMLAFAAEHKRRVQASGDLQRDASLFSNVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=63.8036809815951, Blast_Score=435, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40520; Mature: 40520

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAAIKPVEYDRPGATCGIGQAWAKVPDSPSATERDVLKARIRALLAREKAVLVAHYYVD
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEC
AELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPGKRILMPDLDA
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHHCCCCEEECCCCCC
TCSLDLGCPADEFSAFCDAHPERKVVVYANTSAAVKARADWMVTSSIGLEIVADLHARGE
CEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCHHEEEHHHCCCC
KLIWAPDRHLGNYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRAQYPDAKVLVHPESPE
EEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCCCCC
GVVALADVVGSTTQLIDAAVRLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATC
CEEEEHHHHCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCEEECCCCCCCCCH
KSCAHCPWMAMNGLANLADVLERGHNEIYVDPALGLRARVPIDRMLAFAAEHKRRVQASG
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCC
DLQRDASLFSNVGAA
CHHHHHHHHHHCCCC
>Mature Secondary Structure
MQAAIKPVEYDRPGATCGIGQAWAKVPDSPSATERDVLKARIRALLAREKAVLVAHYYVD
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEC
AELQELADETGGCVADSLEMARFGRDHDAQTLIVAGVRFMGETAKILSPGKRILMPDLDA
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHHCCCCEEECCCCCC
TCSLDLGCPADEFSAFCDAHPERKVVVYANTSAAVKARADWMVTSSIGLEIVADLHARGE
CEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEECCCCHHEEEHHHCCCC
KLIWAPDRHLGNYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRAQYPDAKVLVHPESPE
EEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCCCCC
GVVALADVVGSTTQLIDAAVRLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATC
CEEEEHHHHCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCEEECCCCCCCCCH
KSCAHCPWMAMNGLANLADVLERGHNEIYVDPALGLRARVPIDRMLAFAAEHKRRVQASG
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCC
DLQRDASLFSNVGAA
CHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA