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The map label for this gene is nadB1 [H]

Identifier: 238028406

GI number: 238028406

Start: 3250642

End: 3252222

Strand: Direct

Name: nadB1 [H]

Synonym: bglu_1g28700

Alternate gene names: 238028406

Gene position: 3250642-3252222 (Clockwise)

Preceding gene: 238028405

Following gene: 238028412

Centisome position: 83.21

GC content: 69.58

Gene sequence:

>1581_bases
ATGAATTTCGATGTGGCGATCGTCGGCAGCGGTCTGGCCGGTCTGTCGGTCGCGTTGAACCTGGCGCAGACGCGCCGGGT
CGCGCTGATCGCGAAGCGATCGATGATGGAAGGCGCGAGCGACTACGCGCAGGGCGGCATCGCGGCGGTGCTCGATTCGG
CCGATAGCATCGAGAATCACGTCAGCGACACGCTGATCGCCGGCGGCGGCCTCTGCGACGAGACCACCACGCGCTTCATC
GTCGAGCACGGTCGCGCCGCGATCGAGTGGCTGATCTCGCAGGGCGTGCCGTTCACGCGCGACGCGGCCGCCGAACTCGG
CTTCCACCTGACGCGCGAGGGCGGCCACAGCCATCGGCGCATCATCCACGCGGCCGACGCGACCGGCCACGCCGTGCTTG
CGACGCTGAGCGAGCGCGCGCGCCGCCATCCGAACATCACGTTCTTCGAAAACCACCACGCGATCGACCTCATCACCTCG
GACCGCATCGGCCTCGCGGGCGGGCGCTGCGTCGGGCTCTACGCGCTCGACGTACGCACCGGCCTGACCGTGACGATCGA
GGCGCCGCACACCGTGCTCGCCACCGGCGGCGCCGGCAAGGTCTACCTCTACACGACCAACCCCGACACGGCGACCGGCG
ACGGCATCGCGATGGCCTCGCGCGCGGGCTGCCGCATCGCCAACATGGAGTTCATCCAGTTCCATCCGACCTGCCTCTAC
CATCCGTATGCCAAATCGTTCCTGATCTCGGAGGCGGTGCGCGGCGAGGGCGGCCTGCTGAAGCTGCCCGACGGCACGCG
CTTCATGCCGGCCCATGATGCGCGAGCCGAACTCGCGCCGCGCGACATCGTTGCGCGCGCGATCGACTTCGAGATCAAGA
AGCGCGGCATCGACTGCGTCTACCTCGACATCAGCCACCAGCCCGAGGCGTTCCTGCGCGGGCACTTCCCGACCATCCAC
GCGCGCTGCCTCGAATTCGGCATCGACATCGCGAAGGAGCCGATCCCGGTGGTGCCGGCCGCCCACTACACCTGCGGCGG
CGTGGTCACCGATCTGGCCGGCCGTACCGATCTGGCCGGGCTCTACGCGGTGGGCGAGACGGCTTGCACGGGCCTGCACG
GCGCGAACCGGCTCGCCAGCAACTCGCTGCTCGAATGCCTCGTGATCGGCCGCGCGACCGCCGATGCGATCGAGGCGGCC
GGCTACGAGCCCGCCGCGCACGGCGCGCTGCCGGCCTGGGACGAGAGCCGCGTGTCCGATCCGGACGAGGAGGTGGTGGT
CGCGCACAACTGGGACGAACTGCGCCGGATGATGTGGAACTACGTCGGGATCGTGCGTACCGACAAGCGCCTCGCGCGCG
CCCGACATCGCATCGAGCTGCTGCGCGACGAGATCCACGAGTACTACGCGAACTTCCGCGTCAGCCCCGACCTGCTCGAA
CTGCGCAATCTCGTCGACGTCGCCTCGCTGATCGTCGACAGCGCGCGCTCGCGGCGGGAAAGCCGCGGGCTGCACTACAG
CCGAGACTGGCCGGACACGCTGCCCAAGGCGCTGCCGACCGTGCTGTCGCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
TGTCGGTGACACATCGGTGTGGCGAACGCGGTATGCTCTGCCCTTTCGCGCGGCCCCCGCCGGCGGAAACATCGGATCAA
AGCGTGGAAACGGAGGCAAG

Downstream 100 bases:

>100_bases
GCGCCGCCGGCTGCGCGCCGCCCTAATGCAGCGGGCCGGCGAACCGGCGAATCGGCTCGAAAAACGACGAAGCCGCGCGC
GGACCCTTCCGCGCGCGGCT

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSIENHVSDTLIAGGGLCDETTTRFI
VEHGRAAIEWLISQGVPFTRDAAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITS
DRIGLAGGRCVGLYALDVRTGLTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMASRAGCRIANMEFIQFHPTCLY
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDARAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLRGHFPTIH
ARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETACTGLHGANRLASNSLLECLVIGRATADAIEAA
GYEPAAHGALPAWDESRVSDPDEEVVVAHNWDELRRMMWNYVGIVRTDKRLARARHRIELLRDEIHEYYANFRVSPDLLE
LRNLVDVASLIVDSARSRRESRGLHYSRDWPDTLPKALPTVLSPAR

Sequences:

>Translated_526_residues
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSIENHVSDTLIAGGGLCDETTTRFI
VEHGRAAIEWLISQGVPFTRDAAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITS
DRIGLAGGRCVGLYALDVRTGLTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMASRAGCRIANMEFIQFHPTCLY
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDARAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLRGHFPTIH
ARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETACTGLHGANRLASNSLLECLVIGRATADAIEAA
GYEPAAHGALPAWDESRVSDPDEEVVVAHNWDELRRMMWNYVGIVRTDKRLARARHRIELLRDEIHEYYANFRVSPDLLE
LRNLVDVASLIVDSARSRRESRGLHYSRDWPDTLPKALPTVLSPAR
>Mature_526_residues
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSIENHVSDTLIAGGGLCDETTTRFI
VEHGRAAIEWLISQGVPFTRDAAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITS
DRIGLAGGRCVGLYALDVRTGLTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMASRAGCRIANMEFIQFHPTCLY
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDARAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLRGHFPTIH
ARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETACTGLHGANRLASNSLLECLVIGRATADAIEAA
GYEPAAHGALPAWDESRVSDPDEEVVVAHNWDELRRMMWNYVGIVRTDKRLARARHRIELLRDEIHEYYANFRVSPDLLE
LRNLVDVASLIVDSARSRRESRGLHYSRDWPDTLPKALPTVLSPAR

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=507, Percent_Identity=34.9112426035503, Blast_Score=240, Evalue=2e-63,
Organism=Escherichia coli, GI1788928, Length=526, Percent_Identity=59.8859315589354, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1790597, Length=523, Percent_Identity=36.1376673040153, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1786942, Length=554, Percent_Identity=34.4765342960289, Blast_Score=224, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17550100, Length=528, Percent_Identity=33.5227272727273, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17505833, Length=535, Percent_Identity=33.2710280373832, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71986328, Length=273, Percent_Identity=29.6703296703297, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322701, Length=535, Percent_Identity=34.7663551401869, Blast_Score=243, Evalue=7e-65,
Organism=Saccharomyces cerevisiae, GI6322416, Length=513, Percent_Identity=34.307992202729, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6322511, Length=480, Percent_Identity=27.0833333333333, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320788, Length=482, Percent_Identity=26.9709543568465, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17137288, Length=534, Percent_Identity=33.3333333333333, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24655642, Length=534, Percent_Identity=33.3333333333333, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24655647, Length=534, Percent_Identity=33.3333333333333, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24663005, Length=552, Percent_Identity=32.4275362318841, Blast_Score=224, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 57100; Mature: 57100

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSIENH
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHEECCCHHHHHHH
VSDTLIAGGGLCDETTTRFIVEHGRAAIEWLISQGVPFTRDAAAELGFHLTREGGHSHRR
HHHHEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITSDRIGLAGGRCVGLYALDVRT
EEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCCEEEEEEEEECC
GLTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMASRAGCRIANMEFIQFHPTCLY
CEEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEHHCCCCEEECEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDARAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCEECCCCCCHHHCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLRGHFPTIHARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHCCCCCHHHHHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCH
LYAVGETACTGLHGANRLASNSLLECLVIGRATADAIEAAGYEPAAHGALPAWDESRVSD
HEEECHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
PDEEVVVAHNWDELRRMMWNYVGIVRTDKRLARARHRIELLRDEIHEYYANFRVSPDLLE
CCCCEEEEECHHHHHHHHHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LRNLVDVASLIVDSARSRRESRGLHYSRDWPDTLPKALPTVLSPAR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNFDVAIVGSGLAGLSVALNLAQTRRVALIAKRSMMEGASDYAQGGIAAVLDSADSIENH
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHEECCCHHHHHHH
VSDTLIAGGGLCDETTTRFIVEHGRAAIEWLISQGVPFTRDAAAELGFHLTREGGHSHRR
HHHHEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITSDRIGLAGGRCVGLYALDVRT
EEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCCEEEEEEEEECC
GLTVTIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMASRAGCRIANMEFIQFHPTCLY
CEEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEHHCCCCEEECEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDARAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCEECCCCCCHHHCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLRGHFPTIHARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHCCCCCHHHHHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCH
LYAVGETACTGLHGANRLASNSLLECLVIGRATADAIEAAGYEPAAHGALPAWDESRVSD
HEEECHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
PDEEVVVAHNWDELRRMMWNYVGIVRTDKRLARARHRIELLRDEIHEYYANFRVSPDLLE
CCCCEEEEECHHHHHHHHHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LRNLVDVASLIVDSARSRRESRGLHYSRDWPDTLPKALPTVLSPAR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]