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The map label for this gene is hutU [H]

Identifier: 238028068

GI number: 238028068

Start: 2864997

End: 2866685

Strand: Reverse

Name: hutU [H]

Synonym: bglu_1g25190

Alternate gene names: 238028068

Gene position: 2866685-2864997 (Counterclockwise)

Preceding gene: 238028069

Following gene: 238028067

Centisome position: 73.38

GC content: 69.09

Gene sequence:

>1689_bases
ATGAACCATCCGAACCACATCGATCCGCGTCTGGACCCGACGCGCGTGATCCGCGCGCCGCGCGGTGCCGAGAAGACCTG
CAAGACCTGGCTGGCCGAGGCCGCCTACCGGATGCTGCAGAACAACCTCGACGCCGAGGTGGCCGAGCATCCGCACGCGC
TGGTGGTGTACGGCGGCATCGGCCGCGCCGCGCGCGACTGGGCATGCTTCGACCAGATCCTCGCCTCGCTGAAGGCGCTC
GAGGAGAACGAAACGCTGCTGATCCAGTCGGGCAAGCCGGTCGGCGTGTTCCGCACCCATCCCGACGCGCCGCGCGTACT
GCTGGCGAACTCGAACCTGGTGCCGCACTGGGCCAACTGGGACCACTTCAACGAACTCGACCGCCAGGGCCTGATGATGT
ATGGCCAGATGACGGCGGGCAGCTGGATCTACATCGGCAGCCAGGGGATCGTGCAGGGCACCTACGAAACCTTCTTCTCG
GTGGCCAACCAGCATTTCCACGGCGATCCGTCGGGCCGCTGGATCCTGACCGGGGGACTGGGCGGGATGGGCGGCGCGCA
GCCGCTCGCGGCCACCATGGCGGGCTTCTCGATGATCGCGGTGGAGTGCGACGAGTCGCGGATCGATTTCCGCCTGAAGA
CGCGCTATGTGGACAAGAAGGCGCGCAGCCTGGACGAGGCGCTCGCGCTGCTCGACGAGGCGAAGCGCGGCGGCCGGCCG
GTGTCGATCGGCCTCGTCGGCAACGCGGCCGACGTGTTTGCCGAGGTCGTGGCGCGCGGCATCACGCCGGACTGCGTGAC
GGACCAGACGAGCGCGCACGATCCGGTGAACGGCTACCTGCCGCAGGGCTGGAGCGTGGCGCAGTGGCAGGAGGCGCGCA
AGGTCGATCCGCAGGGCATCGTTGTGCCGGCCAAGCAGTCGATGGCCCGCCAGGTGCAGGCGATGCTGACGCTGCAGCAG
CGCGGCGCGGCCACGCTCGACTACGGCAACAACATCCGCCAGATGGCGCTGGAAATGGGCGTGGCCAACGCGTTCGACTT
TCCGGGCTTCGTGCCGGCCTATATCCGGCCGCTGTTCTGCGAGGGCAAGGGGCCGTTCCGCTGGGTGGCGCTGTCGGGGG
ACCCGGAGGACATCTACAAGACCGACGCGAAGGTCAAGGAGCTGATTCCCGACGATGCGCACCTGCACAACTGGCTCGAC
ATGGCGCGCGAGCGGATCGCGTTCCAGGGGCTGCCGGCGCGGATCTGCTGGGTGGGGGTGAAGGATCGCTATCGCCTGGG
GCAGGCGTTCAACGAGATGGTGAGGCGCGGCGAGCTGAAGGCGCCGATCGTGATCGGCCGGGACCACCTGGACACGGGGT
CGGTGGCGAGCCCGAACCGGGAGACGGAAGCGATGAAGGACGGCTCGGACGCGGTTAGCGACTGGCCGCTGTTGAACGCG
CTGCTGAACACGGCGGGCGGGGCGACCTGGGTGTCGCTGCACCACGGCGGCGGGGTGGGGATGGGCTTTTCGCAGCACGC
GGGCGTGGTGATCGTGGCGGACGGCAGCGAGGCGGCGCACGAGCGGCTGGGCCGCGTGCTGTTCAACGATCCGGCCACGG
GGGTGATGCGCCATGCCGATGCCGGCTATGAACTCGCGCAGCGCACCGCGCGCGAGGCCGGTCTCAAGCTGCCGATGCTG
GGGCGTTGA

Upstream 100 bases:

>100_bases
GGCCATTTCTGAACCGGCACACCCCGGCCGGCGAGCCTCGCGGCACGCCGGCCGGGGTGGCCGTCACGTATCCCTATATT
TCCCTGGAGCGCCGTCGACC

Downstream 100 bases:

>100_bases
GCGCCATGTCGATGGGCCTGGCAGCGCGCCTGTCGCTGATCCGCGCGGATCGACTCGTCGCCGCGCCCTGGAAGAACGGC
GGCGGCGTGACGCGCGAGAT

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MNHPNHIDPRLDPTRVIRAPRGAEKTCKTWLAEAAYRMLQNNLDAEVAEHPHALVVYGGIGRAARDWACFDQILASLKAL
EENETLLIQSGKPVGVFRTHPDAPRVLLANSNLVPHWANWDHFNELDRQGLMMYGQMTAGSWIYIGSQGIVQGTYETFFS
VANQHFHGDPSGRWILTGGLGGMGGAQPLAATMAGFSMIAVECDESRIDFRLKTRYVDKKARSLDEALALLDEAKRGGRP
VSIGLVGNAADVFAEVVARGITPDCVTDQTSAHDPVNGYLPQGWSVAQWQEARKVDPQGIVVPAKQSMARQVQAMLTLQQ
RGAATLDYGNNIRQMALEMGVANAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTDAKVKELIPDDAHLHNWLD
MARERIAFQGLPARICWVGVKDRYRLGQAFNEMVRRGELKAPIVIGRDHLDTGSVASPNRETEAMKDGSDAVSDWPLLNA
LLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVADGSEAAHERLGRVLFNDPATGVMRHADAGYELAQRTAREAGLKLPML
GR

Sequences:

>Translated_562_residues
MNHPNHIDPRLDPTRVIRAPRGAEKTCKTWLAEAAYRMLQNNLDAEVAEHPHALVVYGGIGRAARDWACFDQILASLKAL
EENETLLIQSGKPVGVFRTHPDAPRVLLANSNLVPHWANWDHFNELDRQGLMMYGQMTAGSWIYIGSQGIVQGTYETFFS
VANQHFHGDPSGRWILTGGLGGMGGAQPLAATMAGFSMIAVECDESRIDFRLKTRYVDKKARSLDEALALLDEAKRGGRP
VSIGLVGNAADVFAEVVARGITPDCVTDQTSAHDPVNGYLPQGWSVAQWQEARKVDPQGIVVPAKQSMARQVQAMLTLQQ
RGAATLDYGNNIRQMALEMGVANAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTDAKVKELIPDDAHLHNWLD
MARERIAFQGLPARICWVGVKDRYRLGQAFNEMVRRGELKAPIVIGRDHLDTGSVASPNRETEAMKDGSDAVSDWPLLNA
LLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVADGSEAAHERLGRVLFNDPATGVMRHADAGYELAQRTAREAGLKLPML
GR
>Mature_562_residues
MNHPNHIDPRLDPTRVIRAPRGAEKTCKTWLAEAAYRMLQNNLDAEVAEHPHALVVYGGIGRAARDWACFDQILASLKAL
EENETLLIQSGKPVGVFRTHPDAPRVLLANSNLVPHWANWDHFNELDRQGLMMYGQMTAGSWIYIGSQGIVQGTYETFFS
VANQHFHGDPSGRWILTGGLGGMGGAQPLAATMAGFSMIAVECDESRIDFRLKTRYVDKKARSLDEALALLDEAKRGGRP
VSIGLVGNAADVFAEVVARGITPDCVTDQTSAHDPVNGYLPQGWSVAQWQEARKVDPQGIVVPAKQSMARQVQAMLTLQQ
RGAATLDYGNNIRQMALEMGVANAFDFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTDAKVKELIPDDAHLHNWLD
MARERIAFQGLPARICWVGVKDRYRLGQAFNEMVRRGELKAPIVIGRDHLDTGSVASPNRETEAMKDGSDAVSDWPLLNA
LLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVADGSEAAHERLGRVLFNDPATGVMRHADAGYELAQRTAREAGLKLPML
GR

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=576, Percent_Identity=34.0277777777778, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI260306182, Length=636, Percent_Identity=30.9748427672956, Blast_Score=268, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71997891, Length=571, Percent_Identity=33.2749562171629, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 61407; Mature: 61407

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPNHIDPRLDPTRVIRAPRGAEKTCKTWLAEAAYRMLQNNLDAEVAEHPHALVVYGGI
CCCCCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEECCC
GRAARDWACFDQILASLKALEENETLLIQSGKPVGVFRTHPDAPRVLLANSNLVPHWANW
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCC
DHFNELDRQGLMMYGQMTAGSWIYIGSQGIVQGTYETFFSVANQHFHGDPSGRWILTGGL
CHHHHHHHCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCC
GGMGGAQPLAATMAGFSMIAVECDESRIDFRLKTRYVDKKARSLDEALALLDEAKRGGRP
CCCCCCCHHHHHHCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCE
VSIGLVGNAADVFAEVVARGITPDCVTDQTSAHDPVNGYLPQGWSVAQWQEARKVDPQGI
EEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCE
VVPAKQSMARQVQAMLTLQQRGAATLDYGNNIRQMALEMGVANAFDFPGFVPAYIRPLFC
EECCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHCEEEE
EGKGPFRWVALSGDPEDIYKTDAKVKELIPDDAHLHNWLDMARERIAFQGLPARICWVGV
CCCCCEEEEEECCCHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECC
KDRYRLGQAFNEMVRRGELKAPIVIGRDHLDTGSVASPNRETEAMKDGSDAVSDWPLLNA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVADGSEAAHERLGRVLFNDPATGVMRHAD
HHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHCHHEECCCCHHHHHHCC
AGYELAQRTAREAGLKLPMLGR
CCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNHPNHIDPRLDPTRVIRAPRGAEKTCKTWLAEAAYRMLQNNLDAEVAEHPHALVVYGGI
CCCCCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEECCC
GRAARDWACFDQILASLKALEENETLLIQSGKPVGVFRTHPDAPRVLLANSNLVPHWANW
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCC
DHFNELDRQGLMMYGQMTAGSWIYIGSQGIVQGTYETFFSVANQHFHGDPSGRWILTGGL
CHHHHHHHCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCC
GGMGGAQPLAATMAGFSMIAVECDESRIDFRLKTRYVDKKARSLDEALALLDEAKRGGRP
CCCCCCCHHHHHHCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCE
VSIGLVGNAADVFAEVVARGITPDCVTDQTSAHDPVNGYLPQGWSVAQWQEARKVDPQGI
EEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCE
VVPAKQSMARQVQAMLTLQQRGAATLDYGNNIRQMALEMGVANAFDFPGFVPAYIRPLFC
EECCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHCEEEE
EGKGPFRWVALSGDPEDIYKTDAKVKELIPDDAHLHNWLDMARERIAFQGLPARICWVGV
CCCCCEEEEEECCCHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECC
KDRYRLGQAFNEMVRRGELKAPIVIGRDHLDTGSVASPNRETEAMKDGSDAVSDWPLLNA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVADGSEAAHERLGRVLFNDPATGVMRHAD
HHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHCHHEECCCCHHHHHHCC
AGYELAQRTAREAGLKLPMLGR
CCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]