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The map label for this gene is dapA [H]

Identifier: 238027990

GI number: 238027990

Start: 2772006

End: 2772908

Strand: Reverse

Name: dapA [H]

Synonym: bglu_1g24390

Alternate gene names: 238027990

Gene position: 2772908-2772006 (Counterclockwise)

Preceding gene: 238027991

Following gene: 238027989

Centisome position: 70.98

GC content: 67.22

Gene sequence:

>903_bases
ATGGCTAACGGCACTCAAGACGGTATTCAATTCCGCGGCAGCATTCCCGCGATCGTGACCCCGATGCTCGAAGACGGCAG
CCTCGATCTGCCGACGCTTCGCAAGCTGATCGACTGGCACATCGAGGAGGGCACCGACGGGCTCGTCGTGGTGGGCACGA
GCGGCGAATCGGCGACGCTGTCGGTCGACGAGCACGTGCTGACGATCAAGACGGCGGTGGAGCACGCGGCCGGACGTATC
CCGATCATCGCGGGCGCGGGCGGCAATTCGACCTCGGAGGCGATCGAACTGGCGCGTCACGCGAAATCGGTCGGCGCCGA
CGCCACGCTGCAGGTGGTGCCGTATTACAACAAGCCGACGCAGGAAGGCATGTTCCGCCACTTCCGGGCCATCGCCGAGG
CGGTGGACCTGCCGCTGATCCTCTACAACGTGCCGGGCCGCACGGTGGCCGACATGGACAACGAGACGATCCTGCGGCTT
GCCGAGGTGCCGGGCATCGTCGGCGTGAAGGACGCGACCGGCAACATCGGTCGCGCCGCGCACCTGATCAAGGCGGCGCC
GGCCGGCTTCGGCATCTACAGCGGCGACGATCCGACTGCGATCGCGCTGATGCTGCTGGGCGGCCACGGCAACATCTCGG
TCACCGCCAACGTCGCGCCGCGCGCGATGAGCGAGCTGTGCCGCGCGGCGATCGCCGCCGACGCGAAAACGGCCCGCGAG
ATCCATCTGAAGCTGCTGTCGCTGCACAAGCACCTGTTCGTCGAGGCGAACCCGATTCCGGTGAAGTGGGCGCTGCAGGA
AATGGGCAGGATCCGCGGCGGCATCCGCTTGCCGCTGACGCCGCTCGACGAGCGTCATTACGATGTCGTGCGCGGTGCGC
TGCGCGAAGCCGGCATCGTTTAA

Upstream 100 bases:

>100_bases
GGGAGCGCGCCGCGCAACAAGGGGCGGGATTTCCGCGTTACGGACTGCTCGGGTAATCCGCTACAATCGTCGTTTATTGA
GTTTACTTTCACTGCGTTTC

Downstream 100 bases:

>100_bases
CCGATCCGGGCGGCCGCGCCGCCCGGAGTTTCGATCCACTCCGACTCCTGTCCGGCCCGCCGGCATCGCGCGTCACCCGC
GTTTAGCAAGACGAAGGATT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MANGTQDGIQFRGSIPAIVTPMLEDGSLDLPTLRKLIDWHIEEGTDGLVVVGTSGESATLSVDEHVLTIKTAVEHAAGRI
PIIAGAGGNSTSEAIELARHAKSVGADATLQVVPYYNKPTQEGMFRHFRAIAEAVDLPLILYNVPGRTVADMDNETILRL
AEVPGIVGVKDATGNIGRAAHLIKAAPAGFGIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAAIAADAKTARE
IHLKLLSLHKHLFVEANPIPVKWALQEMGRIRGGIRLPLTPLDERHYDVVRGALREAGIV

Sequences:

>Translated_300_residues
MANGTQDGIQFRGSIPAIVTPMLEDGSLDLPTLRKLIDWHIEEGTDGLVVVGTSGESATLSVDEHVLTIKTAVEHAAGRI
PIIAGAGGNSTSEAIELARHAKSVGADATLQVVPYYNKPTQEGMFRHFRAIAEAVDLPLILYNVPGRTVADMDNETILRL
AEVPGIVGVKDATGNIGRAAHLIKAAPAGFGIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAAIAADAKTARE
IHLKLLSLHKHLFVEANPIPVKWALQEMGRIRGGIRLPLTPLDERHYDVVRGALREAGIV
>Mature_299_residues
ANGTQDGIQFRGSIPAIVTPMLEDGSLDLPTLRKLIDWHIEEGTDGLVVVGTSGESATLSVDEHVLTIKTAVEHAAGRIP
IIAGAGGNSTSEAIELARHAKSVGADATLQVVPYYNKPTQEGMFRHFRAIAEAVDLPLILYNVPGRTVADMDNETILRLA
EVPGIVGVKDATGNIGRAAHLIKAAPAGFGIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAAIAADAKTAREI
HLKLLSLHKHLFVEANPIPVKWALQEMGRIRGGIRLPLTPLDERHYDVVRGALREAGIV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=293, Percent_Identity=23.8907849829352, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI13540533, Length=236, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=50.1718213058419, Blast_Score=291, Evalue=3e-80,
Organism=Escherichia coli, GI87082415, Length=265, Percent_Identity=35.0943396226415, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1786463, Length=280, Percent_Identity=33.5714285714286, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1789620, Length=278, Percent_Identity=29.136690647482, Blast_Score=127, Evalue=9e-31,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31805; Mature: 31674

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGTQDGIQFRGSIPAIVTPMLEDGSLDLPTLRKLIDWHIEEGTDGLVVVGTSGESATL
CCCCCCCCEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
SVDEHVLTIKTAVEHAAGRIPIIAGAGGNSTSEAIELARHAKSVGADATLQVVPYYNKPT
EECCEEEEHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
QEGMFRHFRAIAEAVDLPLILYNVPGRTVADMDNETILRLAEVPGIVGVKDATGNIGRAA
HHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHHCCCEEEECCCCCCCHHHH
HLIKAAPAGFGIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAAIAADAKTARE
HHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCHHHHHH
IHLKLLSLHKHLFVEANPIPVKWALQEMGRIRGGIRLPLTPLDERHYDVVRGALREAGIV
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANGTQDGIQFRGSIPAIVTPMLEDGSLDLPTLRKLIDWHIEEGTDGLVVVGTSGESATL
CCCCCCCEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
SVDEHVLTIKTAVEHAAGRIPIIAGAGGNSTSEAIELARHAKSVGADATLQVVPYYNKPT
EECCEEEEHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
QEGMFRHFRAIAEAVDLPLILYNVPGRTVADMDNETILRLAEVPGIVGVKDATGNIGRAA
HHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHHCCCEEEECCCCCCCHHHH
HLIKAAPAGFGIYSGDDPTAIALMLLGGHGNISVTANVAPRAMSELCRAAIAADAKTARE
HHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCHHHHHH
IHLKLLSLHKHLFVEANPIPVKWALQEMGRIRGGIRLPLTPLDERHYDVVRGALREAGIV
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]