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The map label for this gene is lysC [H]

Identifier: 238027916

GI number: 238027916

Start: 2590519

End: 2591733

Strand: Reverse

Name: lysC [H]

Synonym: bglu_1g23580

Alternate gene names: 238027916

Gene position: 2591733-2590519 (Counterclockwise)

Preceding gene: 238027917

Following gene: 238027915

Centisome position: 66.34

GC content: 63.37

Gene sequence:

>1215_bases
ATGGGCTCGGTCGAGCGCATCAAGAACGTCGCGAAACGCGTCGCGAAATGGCATCGGGCCGGCCACCAGATGGTGGTCGT
GCCGTCGGCGATGTCCGGCGAAACGAACCGCCTGCTCGGTCTCGCGAAAGAGATCTCGAGCCGGCCCGATCCGCGCGAAC
TCGACATGATCGCGTCGACGGGCGAGCAGGTCAGCGTCGGTCTGCTGTCGATCGCGTTGCAGGAACTCGGCATTCCCGCC
GTCAGCTACGCGGGCTGGCAGGTGCCGATCAAGACCGACGATGCATACACGAAGGCGCGCATTCAGTCGATCGACGACGA
GCGCGTGAAGCGCGACCTCGCGGCGGGCAAGGTGGTGATGATCACCGGCTTCCAGGGCGTGGACCCGGCCGGCAACATCA
CCACGCTCGGCCGCGGCGGCTCGGACACCTCGGCGGTCGCGGTGGCCGCGGCGCTGCAGGCCGAGGAATGCCTGATCTAC
ACCGATGTCGATGGCGTCTACACCACCGATCCGCGCGTGGTGGACGGCGCGCGCCGCCTGGACTACGTGACTTTCGAGGA
GATGCTGGAAATGGCCAGCCTCGGCTCGAAGGTGCTGCAGATCCGCTCGGTCGAATTCGCCGGCAAGTACCGTGTGAAGA
CGCGTGTGCTGTCTAGCCTGACCGATCCCCTCATCGCTCTCGACGAAGAAATGAAGTCGGGCACCCTGATTACTTTTGAA
GAAGACGAGACCATGGAAAAGGCAGTCATTTCCGGCATCGCATTTCAGCGCGACGAAGCGCGCATCGTGGTGATGGGCGT
GCCCGACAAGCCCGGTATCGCCTATCAGATCCTTGGCCCGGTGGCCGACGCGAACATCGATGTCGACATGATCATCCAGA
ACCAGAGCGTGGCCGGCAAGACCGACTTCACGTTCACGGTCGGCCGTGGCGACTACCAGCGCGCGATGGAGATCCTGACC
AACCAGGTCAAGGGTCACGTCAACGCCGAGCAGGTGCTGGGCGATCCGAAGGTGTCGAAGGTGTCGGTGGTCGGCGTCGG
CATGCGCTCGCACGTCGGCGTGGCGAGCACGGCGTTCCGCACGCTGTCGGAAGAGGGCATCAACATCCAGATGATCTCGA
CCTCCGAAATCAAGATCTCGATCCTGATCGACGAGAAGTACATGGAACTCGCGGTACGCGCGCTGCACAAGGCGTTCGAA
CTCGATCAGGCGTAA

Upstream 100 bases:

>100_bases
CCGAACGGTGGCGCGGCTTGCGGCGCAGTGTATCTGCGCGGTCAATTTCCAGTTCAGAACGACAATGTCACTCATCGTAC
ATAAATACGGCGGCACCTCG

Downstream 100 bases:

>100_bases
GCGGCGCGAATTACCGCCGGATTCGTGGCCGCGGCGGCGCGAAAAAGCGTGCCGAAACATTTGACCTTCGTGCCGGGGCC
ATATAGAATCTTGTTCTCGT

Product: asparate kinase, monofunctional class

Products: NA

Alternate protein names: Aspartate kinase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MGSVERIKNVAKRVAKWHRAGHQMVVVPSAMSGETNRLLGLAKEISSRPDPRELDMIASTGEQVSVGLLSIALQELGIPA
VSYAGWQVPIKTDDAYTKARIQSIDDERVKRDLAAGKVVMITGFQGVDPAGNITTLGRGGSDTSAVAVAAALQAEECLIY
TDVDGVYTTDPRVVDGARRLDYVTFEEMLEMASLGSKVLQIRSVEFAGKYRVKTRVLSSLTDPLIALDEEMKSGTLITFE
EDETMEKAVISGIAFQRDEARIVVMGVPDKPGIAYQILGPVADANIDVDMIIQNQSVAGKTDFTFTVGRGDYQRAMEILT
NQVKGHVNAEQVLGDPKVSKVSVVGVGMRSHVGVASTAFRTLSEEGINIQMISTSEIKISILIDEKYMELAVRALHKAFE
LDQA

Sequences:

>Translated_404_residues
MGSVERIKNVAKRVAKWHRAGHQMVVVPSAMSGETNRLLGLAKEISSRPDPRELDMIASTGEQVSVGLLSIALQELGIPA
VSYAGWQVPIKTDDAYTKARIQSIDDERVKRDLAAGKVVMITGFQGVDPAGNITTLGRGGSDTSAVAVAAALQAEECLIY
TDVDGVYTTDPRVVDGARRLDYVTFEEMLEMASLGSKVLQIRSVEFAGKYRVKTRVLSSLTDPLIALDEEMKSGTLITFE
EDETMEKAVISGIAFQRDEARIVVMGVPDKPGIAYQILGPVADANIDVDMIIQNQSVAGKTDFTFTVGRGDYQRAMEILT
NQVKGHVNAEQVLGDPKVSKVSVVGVGMRSHVGVASTAFRTLSEEGINIQMISTSEIKISILIDEKYMELAVRALHKAFE
LDQA
>Mature_403_residues
GSVERIKNVAKRVAKWHRAGHQMVVVPSAMSGETNRLLGLAKEISSRPDPRELDMIASTGEQVSVGLLSIALQELGIPAV
SYAGWQVPIKTDDAYTKARIQSIDDERVKRDLAAGKVVMITGFQGVDPAGNITTLGRGGSDTSAVAVAAALQAEECLIYT
DVDGVYTTDPRVVDGARRLDYVTFEEMLEMASLGSKVLQIRSVEFAGKYRVKTRVLSSLTDPLIALDEEMKSGTLITFEE
DETMEKAVISGIAFQRDEARIVVMGVPDKPGIAYQILGPVADANIDVDMIIQNQSVAGKTDFTFTVGRGDYQRAMEILTN
QVKGHVNAEQVLGDPKVSKVSVVGVGMRSHVGVASTAFRTLSEEGINIQMISTSEIKISILIDEKYMELAVRALHKAFEL
DQA

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ACT domains [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=316, Percent_Identity=30.6962025316456, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790455, Length=381, Percent_Identity=28.0839895013123, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790376, Length=160, Percent_Identity=31.25, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320893, Length=402, Percent_Identity=26.865671641791, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase; PF01842 ACT [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 43762; Mature: 43631

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVERIKNVAKRVAKWHRAGHQMVVVPSAMSGETNRLLGLAKEISSRPDPRELDMIAST
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCC
GEQVSVGLLSIALQELGIPAVSYAGWQVPIKTDDAYTKARIQSIDDERVKRDLAAGKVVM
CCHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCEEE
ITGFQGVDPAGNITTLGRGGSDTSAVAVAAALQAEECLIYTDVDGVYTTDPRVVDGARRL
EECCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCEECCHHHC
DYVTFEEMLEMASLGSKVLQIRSVEFAGKYRVKTRVLSSLTDPLIALDEEMKSGTLITFE
CHHHHHHHHHHHHHCHHHEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEC
EDETMEKAVISGIAFQRDEARIVVMGVPDKPGIAYQILGPVADANIDVDMIIQNQSVAGK
CCHHHHHHHHHHHHEECCCCEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCC
TDFTFTVGRGDYQRAMEILTNQVKGHVNAEQVLGDPKVSKVSVVGVGMRSHVGVASTAFR
CCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEECHHHCCCHHHHHHH
TLSEEGINIQMISTSEIKISILIDEKYMELAVRALHKAFELDQA
HHHHCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GSVERIKNVAKRVAKWHRAGHQMVVVPSAMSGETNRLLGLAKEISSRPDPRELDMIAST
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCC
GEQVSVGLLSIALQELGIPAVSYAGWQVPIKTDDAYTKARIQSIDDERVKRDLAAGKVVM
CCHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCEEE
ITGFQGVDPAGNITTLGRGGSDTSAVAVAAALQAEECLIYTDVDGVYTTDPRVVDGARRL
EECCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCEECCHHHC
DYVTFEEMLEMASLGSKVLQIRSVEFAGKYRVKTRVLSSLTDPLIALDEEMKSGTLITFE
CHHHHHHHHHHHHHCHHHEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEC
EDETMEKAVISGIAFQRDEARIVVMGVPDKPGIAYQILGPVADANIDVDMIIQNQSVAGK
CCHHHHHHHHHHHHEECCCCEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCC
TDFTFTVGRGDYQRAMEILTNQVKGHVNAEQVLGDPKVSKVSVVGVGMRSHVGVASTAFR
CCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEECHHHCCCHHHHHHH
TLSEEGINIQMISTSEIKISILIDEKYMELAVRALHKAFELDQA
HHHHCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]