| Definition | Burkholderia glumae BGR1 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_012724 |
| Length | 3,906,507 |
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The map label for this gene is ywfH [H]
Identifier: 238027854
GI number: 238027854
Start: 2493677
End: 2494447
Strand: Reverse
Name: ywfH [H]
Synonym: bglu_1g22850
Alternate gene names: 238027854
Gene position: 2494447-2493677 (Counterclockwise)
Preceding gene: 238027855
Following gene: 238027852
Centisome position: 63.85
GC content: 71.6
Gene sequence:
>771_bases ATGGATCTCGGTATCAACGGCCGCGCGGCGCTCGTCACGGGCGCATCGAAGGGCATCGGTCTCGCGAGCGCGATGGCGCT GGCCAGGGAGGGATGCGGCGTGCATCTGGTGTCGTCCAACGCCGAGGCGATCGAGCGCGCGAAGCGCGCGGTCGAGGCGG CCTTCCCAGTGCCGTTGCGCGCCACCGCGCTCGATCTGGCGGATTCGCGCTCACGCGAGCAACTGCTCGCCTCGGCCGGC CCGATCGACATCCTCGTCAACAACGCCGGCGCGATCCCGGGCGGCGGCCTCGATGCCGTCGACGAGGCCGCATGGCGCGC GGCATGGGAGCTGAAGCTGTTCGGCTATATGGATTTCGCCCGGCTCGCGCTGCCGGCGATGATGGCACGCGGCAGCGGCG TGATCGTCAACGTGATCGGCGCGGCCGGCGTGGCGCCGCGCTACGACTACATCCTCGGCTCGACGGCCAACGCCGCGCTG GTCGCGTTTACCCAGGCGGTCGGCGCGCAGGCGACGACGCGCGGGGTGCGCATGGTCGGCATCAATCCGGGGCCGTGCGC CACCGAGCGGCTCGAGACGCTCTACCGGCGCCGTGCGCAGACGGCATTCGGCGACGCCTCGCGCTGGCGCGAACTGCTCG ATGCGCTGCCGTTCGGCCGGCCCTCCGAGCCCGAGGAGATGGCCGACCTGGTGGCGTTCCTCGCTTCCGAGCGCGCTTCA TACCTGAGCGGCGTGGTGATCGACGCGGACGGCGGGGCGAAGTATCGGTGA
Upstream 100 bases:
>100_bases GCGCGCGCGCCGCTTCGCGCCGACGTACCATGCGGCATCCACGCAGCACGCGCGTCGTCGCCGCCGCGGCACGTGGTTTC ATCATGAACGGGAGTAGGAC
Downstream 100 bases:
>100_bases GCGGGCCGGGCGGCGCGGACCAGCGCGGCCCGGCTGCAGCGGGAGCCGCGCCCGACCTCTGCCGGGTCGGTGCCGGACCG GCGCCGAGCGCGCGCCCTCA
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MDLGINGRAALVTGASKGIGLASAMALAREGCGVHLVSSNAEAIERAKRAVEAAFPVPLRATALDLADSRSREQLLASAG PIDILVNNAGAIPGGGLDAVDEAAWRAAWELKLFGYMDFARLALPAMMARGSGVIVNVIGAAGVAPRYDYILGSTANAAL VAFTQAVGAQATTRGVRMVGINPGPCATERLETLYRRRAQTAFGDASRWRELLDALPFGRPSEPEEMADLVAFLASERAS YLSGVVIDADGGAKYR
Sequences:
>Translated_256_residues MDLGINGRAALVTGASKGIGLASAMALAREGCGVHLVSSNAEAIERAKRAVEAAFPVPLRATALDLADSRSREQLLASAG PIDILVNNAGAIPGGGLDAVDEAAWRAAWELKLFGYMDFARLALPAMMARGSGVIVNVIGAAGVAPRYDYILGSTANAAL VAFTQAVGAQATTRGVRMVGINPGPCATERLETLYRRRAQTAFGDASRWRELLDALPFGRPSEPEEMADLVAFLASERAS YLSGVVIDADGGAKYR >Mature_256_residues MDLGINGRAALVTGASKGIGLASAMALAREGCGVHLVSSNAEAIERAKRAVEAAFPVPLRATALDLADSRSREQLLASAG PIDILVNNAGAIPGGGLDAVDEAAWRAAWELKLFGYMDFARLALPAMMARGSGVIVNVIGAAGVAPRYDYILGSTANAAL VAFTQAVGAQATTRGVRMVGINPGPCATERLETLYRRRAQTAFGDASRWRELLDALPFGRPSEPEEMADLVAFLASERAS YLSGVVIDADGGAKYR
Specific function: Along with the bacABCDE operon is involved in bacilysin biosynthesis [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=27.9527559055118, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=28.4584980237154, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=25.8687258687259, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=31.0679611650485, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=26.4462809917355, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=26.4550264550265, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=27.5590551181102, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=30.8139534883721, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=30, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=26.6393442622951, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=28.0769230769231, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=30.5343511450382, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=26.5384615384615, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87082160, Length=271, Percent_Identity=26.9372693726937, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=29.277566539924, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=24, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=27.6679841897233, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=26.171875, Blast_Score=64, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=28.6259541984733, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=33.5820895522388, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=28.7878787878788, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=30.3030303030303, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=30.0751879699248, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.4615384615385, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=29.8449612403101, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=29.0076335877863, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=30.188679245283, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI193204405, Length=276, Percent_Identity=29.7101449275362, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=26.7175572519084, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.9693486590038, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=28.7313432835821, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=28.8321167883212, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=28.2442748091603, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.3582089552239, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.4393939393939, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=26.1044176706827, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=25.0909090909091, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=25.3846153846154, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560220, Length=277, Percent_Identity=25.6317689530686, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=25.4980079681275, Blast_Score=70, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=26.8, Blast_Score=66, Evalue=4e-12, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32.8, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.9212598425197, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.952380952381, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI21355319, Length=266, Percent_Identity=31.203007518797, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=28.9473684210526, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=27.9245283018868, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=29.7979797979798, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355631, Length=150, Percent_Identity=30.6666666666667, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26675; Mature: 26675
Theoretical pI: Translated: 6.03; Mature: 6.03
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLGINGRAALVTGASKGIGLASAMALAREGCGVHLVSSNAEAIERAKRAVEAAFPVPLR CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCH ATALDLADSRSREQLLASAGPIDILVNNAGAIPGGGLDAVDEAAWRAAWELKLFGYMDFA HHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEHHHHHHH RLALPAMMARGSGVIVNVIGAAGVAPRYDYILGSTANAALVAFTQAVGAQATTRGVRMVG HHHHHHHHHCCCCEEEEECCCCCCCCCHHHEECCCCCHHHHHHHHHHCCCHHHCCEEEEE INPGPCATERLETLYRRRAQTAFGDASRWRELLDALPFGRPSEPEEMADLVAFLASERAS CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH YLSGVVIDADGGAKYR HHCCEEEECCCCCCCC >Mature Secondary Structure MDLGINGRAALVTGASKGIGLASAMALAREGCGVHLVSSNAEAIERAKRAVEAAFPVPLR CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCH ATALDLADSRSREQLLASAGPIDILVNNAGAIPGGGLDAVDEAAWRAAWELKLFGYMDFA HHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEHHHHHHH RLALPAMMARGSGVIVNVIGAAGVAPRYDYILGSTANAALVAFTQAVGAQATTRGVRMVG HHHHHHHHHCCCCEEEEECCCCCCCCCHHHEECCCCCHHHHHHHHHHCCCHHHCCEEEEE INPGPCATERLETLYRRRAQTAFGDASRWRELLDALPFGRPSEPEEMADLVAFLASERAS CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH YLSGVVIDADGGAKYR HHCCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7934828; 9384377 [H]