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The map label for this gene is gltT [H]

Identifier: 238027840

GI number: 238027840

Start: 2480332

End: 2481579

Strand: Reverse

Name: gltT [H]

Synonym: bglu_1g22710

Alternate gene names: 238027840

Gene position: 2481579-2480332 (Counterclockwise)

Preceding gene: 238027841

Following gene: 238027839

Centisome position: 63.52

GC content: 67.39

Gene sequence:

>1248_bases
ATGAATCAAAAGAATAGCAGGACCTCGCTGCCACTGATCATGATCGTCGCGCTGATTCTCGGCGCGTTCACCGGCGTGTA
CGCCCCGCGTTTCTCGGCCGACGTCGGCTTCCTCTCGACGCTGTTCGGCCACGCCATCAAGATGGTGGTGATGCCGCTGA
TCCTGCTGTCGGTGGTGGTGGGCAGCTATCGCGCCGTCGAGCAGCGCCGCCACCTCGGGCGCACGGCCGTGATCGCGATC
CTGTTCTTCATCGTCATGACGGTCGTGTCGAGCGCGCTCGGGCTCGGTCTCTACTGGCTGTTCCGTCCGGGCCTCGGCGC
CTCGATGACGGGCTCGGGCGCGCTGCCCGACCATCTCGCCACCAGCATCGACTGGATCAAGTTCATCACCGACATGGTGC
CGCAGAACCTGGTGGCCGCGCTCTCGTCGGGCAACGCGATTCCGGTGCTGGTGTTCGGCGTGATGCTCGGCACCGCGCTC
GGCGCCACCGGCGAAGCGGGGCGCCCCGCGATCAACCTGTTCGCCTCGCTGCTGGCCGGCCTGTTCAAGATGGTCGAGTG
GATCGTCGCGCTCTCGCCGCTGGCGATCTTCGCGGCGGTGGCCGGGCTGATGAGCAGCCGCGGCGTGGCCGGCCTGATGC
CGCTCGTCAAGCTGCTCGGCATCGCCTATCTGGGCATGGCGATCCTGGCCGTGCTGCTGACCCTGATCATCGTGGCCACC
GGCAACCGGCCGCTCGCCGTGATCCGCAAGGTCAGCGAGCCGCTGATTCTCGCCTTCACCACGCGCTCGTCGGAAATCAC
CTATCCGGTGCATCTGAAGAAGCTGACGGAGATGGGCGTGCCGTCCTCGATCGCCTCCACCATCCTGCCGCTGTCCTACA
TCTTCAACCGCGACGGCGCGGTGCTCTATACCGCGCTCGCGGTCGGCTATCTGGCCGACGCCTATCACGTGGTCTGGAGC
TGGCCGCTGGCGCTGACGATTCTCGCGCTGACGATCCTCACCATCGACGGCGCCGCGAACGTGCCGTCGGGCGCGATCGT
CGCGATCACCATCGTGCTGGCCGCGGTGGGGCTGCCCGCCGAGGCGGTGCTGCTGATCCTCGGCGTGGACGCGTTCTTCG
ACATGGGCCGCACGGCCATGAACGTCTACGCGAGCACGGTGGCGATGACGGTGTCGCTGCGCCTGTCGAGCGACGAACGG
ATCACGGCGGCCGAGGGCGTCGACGGCGCCGCTTCGTACCGGACCTGA

Upstream 100 bases:

>100_bases
TCCGCGATCCGCGACGGGCAACCCGAGGAAGCCCGCGGTCACATGTGGAATCACATCGTGGATGGCACCCCTGCAAGAAT
CAAATTAATCCGGGCCAGAA

Downstream 100 bases:

>100_bases
TCGACCCGCGCCGGGCGGGCCCGCCTGCGCGGGCGTCCGGCGCCGTGACGCGAGGCACGCCGCGCGCCGGCCTGATGAAG
GCGGCACGGCTTCGCCCCGC

Product: Sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MNQKNSRTSLPLIMIVALILGAFTGVYAPRFSADVGFLSTLFGHAIKMVVMPLILLSVVVGSYRAVEQRRHLGRTAVIAI
LFFIVMTVVSSALGLGLYWLFRPGLGASMTGSGALPDHLATSIDWIKFITDMVPQNLVAALSSGNAIPVLVFGVMLGTAL
GATGEAGRPAINLFASLLAGLFKMVEWIVALSPLAIFAAVAGLMSSRGVAGLMPLVKLLGIAYLGMAILAVLLTLIIVAT
GNRPLAVIRKVSEPLILAFTTRSSEITYPVHLKKLTEMGVPSSIASTILPLSYIFNRDGAVLYTALAVGYLADAYHVVWS
WPLALTILALTILTIDGAANVPSGAIVAITIVLAAVGLPAEAVLLILGVDAFFDMGRTAMNVYASTVAMTVSLRLSSDER
ITAAEGVDGAASYRT

Sequences:

>Translated_415_residues
MNQKNSRTSLPLIMIVALILGAFTGVYAPRFSADVGFLSTLFGHAIKMVVMPLILLSVVVGSYRAVEQRRHLGRTAVIAI
LFFIVMTVVSSALGLGLYWLFRPGLGASMTGSGALPDHLATSIDWIKFITDMVPQNLVAALSSGNAIPVLVFGVMLGTAL
GATGEAGRPAINLFASLLAGLFKMVEWIVALSPLAIFAAVAGLMSSRGVAGLMPLVKLLGIAYLGMAILAVLLTLIIVAT
GNRPLAVIRKVSEPLILAFTTRSSEITYPVHLKKLTEMGVPSSIASTILPLSYIFNRDGAVLYTALAVGYLADAYHVVWS
WPLALTILALTILTIDGAANVPSGAIVAITIVLAAVGLPAEAVLLILGVDAFFDMGRTAMNVYASTVAMTVSLRLSSDER
ITAAEGVDGAASYRT
>Mature_415_residues
MNQKNSRTSLPLIMIVALILGAFTGVYAPRFSADVGFLSTLFGHAIKMVVMPLILLSVVVGSYRAVEQRRHLGRTAVIAI
LFFIVMTVVSSALGLGLYWLFRPGLGASMTGSGALPDHLATSIDWIKFITDMVPQNLVAALSSGNAIPVLVFGVMLGTAL
GATGEAGRPAINLFASLLAGLFKMVEWIVALSPLAIFAAVAGLMSSRGVAGLMPLVKLLGIAYLGMAILAVLLTLIIVAT
GNRPLAVIRKVSEPLILAFTTRSSEITYPVHLKKLTEMGVPSSIASTILPLSYIFNRDGAVLYTALAVGYLADAYHVVWS
WPLALTILALTILTIDGAANVPSGAIVAITIVLAAVGLPAEAVLLILGVDAFFDMGRTAMNVYASTVAMTVSLRLSSDER
ITAAEGVDGAASYRT

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI21314632, Length=384, Percent_Identity=29.6875, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI169790839, Length=305, Percent_Identity=29.1803278688525, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5032093, Length=369, Percent_Identity=29.5392953929539, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4827012, Length=267, Percent_Identity=31.4606741573034, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI223468564, Length=243, Percent_Identity=32.5102880658436, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI223468566, Length=243, Percent_Identity=32.5102880658436, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI40254478, Length=427, Percent_Identity=23.8875878220141, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI194239697, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI66773030, Length=388, Percent_Identity=25.2577319587629, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790514, Length=416, Percent_Identity=31.4903846153846, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789947, Length=392, Percent_Identity=30.3571428571429, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1788024, Length=381, Percent_Identity=26.7716535433071, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789473, Length=397, Percent_Identity=25.4408060453401, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=437, Percent_Identity=27.0022883295195, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17537407, Length=405, Percent_Identity=26.6666666666667, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71983099, Length=432, Percent_Identity=26.8518518518519, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71983106, Length=432, Percent_Identity=26.8518518518519, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193206654, Length=412, Percent_Identity=25.7281553398058, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193206505, Length=425, Percent_Identity=25.4117647058824, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17541374, Length=403, Percent_Identity=25.8064516129032, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583025, Length=429, Percent_Identity=24.9417249417249, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17137668, Length=429, Percent_Identity=24.9417249417249, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24583023, Length=429, Percent_Identity=24.9417249417249, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281360483, Length=424, Percent_Identity=23.8207547169811, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17137666, Length=424, Percent_Identity=23.8207547169811, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281360481, Length=424, Percent_Identity=23.8207547169811, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43530; Mature: 43530

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEECCCCCEEHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEECCCCCEEHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1359385 [H]