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The map label for this gene is mro [H]

Identifier: 238027793

GI number: 238027793

Start: 2415992

End: 2417062

Strand: Direct

Name: mro [H]

Synonym: bglu_1g22170

Alternate gene names: 238027793

Gene position: 2415992-2417062 (Clockwise)

Preceding gene: 238027792

Following gene: 238027794

Centisome position: 61.85

GC content: 72.74

Gene sequence:

>1071_bases
TTGAGCGCAATCCCATCGACGCCGGCCTTCGGGCCGGCCGGTCAGCGTGTCTCGTCGCGGCCGTGGGGCCGCCTGCCCGG
CGGCGACCCGGTGCGCCTCTTCACGCTGCGCAACGCCCACGGCATGCGGGTGGCGATCAGCGACCTCGGCGCGACGCTGG
TGTCGTGGCAGACGCCCGACCGCGGCGGCCGGCTCGGCGAGATCCTGCTCGGCTTCGACGCGCCGGCCGCCTACCTCGAT
TCGCGCGCCTATCTCGGCGCGCTGGTGGGGCGCTGCTCGAACCGCATCGCGGGCGCGCGCTTCACGCTCGACGGCATCGA
CTACCCGCTCGACCGCAACGACGGCGAGCAGTGCCTGCACGGCGGCCTGAGCGGCTTTCACCGCGCGCTGTGGGAGGCCG
ACATGCTCGACGACGCGCTGCTGATGCGGCTCGTCTCGCCCGAGGGCGACGGCGGGTTCCCCGGCAACGTCGAGGTGCAG
GTGCGCTATGCGCTCGATGACGACGGCACGCTGTCGATCGGCTATGAGGCGCGCGCCGACGCGCCCACGCCGCTGCAGCT
GACGAGCCATCCGTATTTCAACCTGAGCGGGCGCCCGCGTGCCGACATCGACGGGCACGTCCTGACGATCGACGCCGACC
GCTATCTGGAAGTGGACGCGCGGATGATCCCGACGCGGCTCGCGAGCGTGGCCGGCACCGCGTTCGATTTCCGCCAGAGC
GCGCCGCTCGGCGCGCGGCTCGGCTGGCCGCATGCGCAGCTCGCGCTGGCGGGCGGCTTCGACCACTGCTTCGCGCTGCG
CGAGGCCGAAGGCGACGGCGGCGTGCGCGCCGTGGCGCGCGTCTACGATCCCGGCAGCGGCCGCGAGCTAACGGTGCTGA
CCGACCAGCCGGGCCTGCAGCTTTATACGGGCAATTCGCTGGCGGGCCTGCACGGGCCGCGCAGCGCGCTGTGCCTGGAA
GCGGGTGCGTTCCCGAACCAGATCAATTCGGAAGACGCCGAGGCGGTGGTGCTGCGCCCCGGCGAGGTGTATCGGCAGGA
CACGCGGTATCGGGTGGCGGTGGCGGGATAA

Upstream 100 bases:

>100_bases
GCGGCTTCACCTCGACGCAATACATGTACGCGGTGTTCCGGCGCGAGCTCGACTGCACGCCGCGCGAATACCAGGAACGC
ACGCTGTCCGGAGGCCATGC

Downstream 100 bases:

>100_bases
ACAGCCGTGTGCGTGGCTGGCCCCTGCGTCGTCGACTGCAACGACGCCGACAAAAGAGGCCAACGGCCCTGACGTCTATC
CCACCGTCAGCGTCTTCGGC

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSAIPSTPAFGPAGQRVSSRPWGRLPGGDPVRLFTLRNAHGMRVAISDLGATLVSWQTPDRGGRLGEILLGFDAPAAYLD
SRAYLGALVGRCSNRIAGARFTLDGIDYPLDRNDGEQCLHGGLSGFHRALWEADMLDDALLMRLVSPEGDGGFPGNVEVQ
VRYALDDDGTLSIGYEARADAPTPLQLTSHPYFNLSGRPRADIDGHVLTIDADRYLEVDARMIPTRLASVAGTAFDFRQS
APLGARLGWPHAQLALAGGFDHCFALREAEGDGGVRAVARVYDPGSGRELTVLTDQPGLQLYTGNSLAGLHGPRSALCLE
AGAFPNQINSEDAEAVVLRPGEVYRQDTRYRVAVAG

Sequences:

>Translated_356_residues
MSAIPSTPAFGPAGQRVSSRPWGRLPGGDPVRLFTLRNAHGMRVAISDLGATLVSWQTPDRGGRLGEILLGFDAPAAYLD
SRAYLGALVGRCSNRIAGARFTLDGIDYPLDRNDGEQCLHGGLSGFHRALWEADMLDDALLMRLVSPEGDGGFPGNVEVQ
VRYALDDDGTLSIGYEARADAPTPLQLTSHPYFNLSGRPRADIDGHVLTIDADRYLEVDARMIPTRLASVAGTAFDFRQS
APLGARLGWPHAQLALAGGFDHCFALREAEGDGGVRAVARVYDPGSGRELTVLTDQPGLQLYTGNSLAGLHGPRSALCLE
AGAFPNQINSEDAEAVVLRPGEVYRQDTRYRVAVAG
>Mature_355_residues
SAIPSTPAFGPAGQRVSSRPWGRLPGGDPVRLFTLRNAHGMRVAISDLGATLVSWQTPDRGGRLGEILLGFDAPAAYLDS
RAYLGALVGRCSNRIAGARFTLDGIDYPLDRNDGEQCLHGGLSGFHRALWEADMLDDALLMRLVSPEGDGGFPGNVEVQV
RYALDDDGTLSIGYEARADAPTPLQLTSHPYFNLSGRPRADIDGHVLTIDADRYLEVDARMIPTRLASVAGTAFDFRQSA
PLGARLGWPHAQLALAGGFDHCFALREAEGDGGVRAVARVYDPGSGRELTVLTDQPGLQLYTGNSLAGLHGPRSALCLEA
GAFPNQINSEDAEAVVLRPGEVYRQDTRYRVAVAG

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=349, Percent_Identity=40.1146131805158, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1786971, Length=337, Percent_Identity=40.9495548961424, Blast_Score=215, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17557428, Length=329, Percent_Identity=29.7872340425532, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI115533334, Length=329, Percent_Identity=29.7872340425532, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=26.9005847953216, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6322004, Length=351, Percent_Identity=29.6296296296296, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324399, Length=346, Percent_Identity=26.878612716763, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24659048, Length=348, Percent_Identity=36.4942528735632, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24583720, Length=338, Percent_Identity=35.7988165680473, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24668278, Length=368, Percent_Identity=33.4239130434783, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24668282, Length=343, Percent_Identity=34.1107871720117, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24641876, Length=345, Percent_Identity=28.9855072463768, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 38049; Mature: 37918

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIPSTPAFGPAGQRVSSRPWGRLPGGDPVRLFTLRNAHGMRVAISDLGATLVSWQTPD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCC
RGGRLGEILLGFDAPAAYLDSRAYLGALVGRCSNRIAGARFTLDGIDYPLDRNDGEQCLH
CCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHH
GGLSGFHRALWEADMLDDALLMRLVSPEGDGGFPGNVEVQVRYALDDDGTLSIGYEARAD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCCCC
APTPLQLTSHPYFNLSGRPRADIDGHVLTIDADRYLEVDARMIPTRLASVAGTAFDFRQS
CCCCEEECCCCEECCCCCCCCCCCCEEEEEECCCEEEECHHHHHHHHHHHHCCHHHHHCC
APLGARLGWPHAQLALAGGFDHCFALREAEGDGGVRAVARVYDPGSGRELTVLTDQPGLQ
CCCCCCCCCCCCEEEEECCCHHEEEEEECCCCCCEEEEEEEECCCCCCEEEEEECCCCEE
LYTGNSLAGLHGPRSALCLEAGAFPNQINSEDAEAVVLRPGEVYRQDTRYRVAVAG
EEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHCCCCEEEEEEC
>Mature Secondary Structure 
SAIPSTPAFGPAGQRVSSRPWGRLPGGDPVRLFTLRNAHGMRVAISDLGATLVSWQTPD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCC
RGGRLGEILLGFDAPAAYLDSRAYLGALVGRCSNRIAGARFTLDGIDYPLDRNDGEQCLH
CCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHH
GGLSGFHRALWEADMLDDALLMRLVSPEGDGGFPGNVEVQVRYALDDDGTLSIGYEARAD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCCCC
APTPLQLTSHPYFNLSGRPRADIDGHVLTIDADRYLEVDARMIPTRLASVAGTAFDFRQS
CCCCEEECCCCEECCCCCCCCCCCCEEEEEECCCEEEECHHHHHHHHHHHHCCHHHHHCC
APLGARLGWPHAQLALAGGFDHCFALREAEGDGGVRAVARVYDPGSGRELTVLTDQPGLQ
CCCCCCCCCCCCEEEEECCCHHEEEEEECCCCCCEEEEEEEECCCCCCEEEEEECCCCEE
LYTGNSLAGLHGPRSALCLEAGAFPNQINSEDAEAVVLRPGEVYRQDTRYRVAVAG
EEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3012466; 3531172 [H]