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The map label for this gene is nanT [H]

Identifier: 238027548

GI number: 238027548

Start: 2149247

End: 2150473

Strand: Direct

Name: nanT [H]

Synonym: bglu_1g19660

Alternate gene names: 238027548

Gene position: 2149247-2150473 (Clockwise)

Preceding gene: 238027538

Following gene: 238027549

Centisome position: 55.02

GC content: 65.36

Gene sequence:

>1227_bases
ATGAGCTGGACCCGGGAACAGAGAAACGTGACGATCGCCGCCTATTTGGGCTGGACCCTCGACGCATTCGATTTCTTTCT
GATGGTATTCGTGTTGAAAGACATCGCGGCGGAATTCAATACCAAGATCTCGACGGTCACCTTCGCGATCAGCCTGACGC
TGGCCATGCGGCCGGTCGGTGCCCTGATCTTCGGCCGGCTCGCCGACCGCTTCGGCCGCCGCCCCACGCTGATGGTCAAC
ATCGCCCTCTACTCGCTGCTCGAACTCGCCTCGGGCTTCGCGCCGAACCTCACCGCGCTGTTCGTGATGCGCGCGCTGTT
CGGCATCGCGATGGGCGGCGAATGGGGCGTGGGCTCCGCGCTGACGATGGAAACGGTGCCGCCCAAATCGCGCGGCATCG
TCTCCGGGCTGCTGCAGGCCGGCTATCCGAGCGGTTATCTGCTCGCCTCGATCGTGTTCGGCCTGTTCTATCAGTACATC
GGCTGGCGCGGCATGTTCATGATCGGCGTGCTGCCCGCGCTGCTGGTGCTTTACGTGCGCTCGCACGTGCCTGAATCGCC
GGCCTGGAAGCAGATGGAGAAGCGGCCGCGCCCGAGCCTCGTGGCCACGCTGCGGCATAACTGGAAGCTGTCGATCTACG
CGGTGGTGCTGATGACCGCGTTCAACTTCTTCTCGCACGGCACGCAGGATCTGTATCCGACCTTCCTGCGCGAACAGCAT
CACTTCGATCCGCATACCGTGTCGTGGATCACGATCGTGCTGAACATCGGCGCGATCGTCGGCGGCCTCGCGTTCGGCTC
GCTTTCCGAGAAGATCGGCCGGCGCCGCGCCATCTTCATCGCCGCGCTGATCGCCCTGCCGGTGCTGCCGCTCTGGGCGT
TCTCGAGCGGCACCGTGGCGCTCGCGGCCGGCGCGTTCCTGATGCAGATCTCGGTGCAGGGCGCCTGGGGCGTTATCCCG
GTCCACTTGAACGAGATCTCGCCGGACGAGATTCGCGCCACCTTCCCCGGCTTCGTCTACCAGCTCGGCAATCTGATCGC
CTCGGGCAATGCGGTGATGCAGGCGCGACTGGCCTCCAGCAACGGCAACGGCAACGACTACAGCTACGCGCTCGCGCTGG
TGGCTGGCGTGGTGGCGGTGGTGATCGCCTCGCTGATCCTGTTCAGCCGCGAACGGCGCGGCATCGACATGACGCAGAGC
GCCGCGCGGGTCTCCTCGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGACGCGCAAACCATTCCGCGGCGTACACTCGATCCGCCGCGCGCCCCGCCGGGCGGCCCTCGCCGCCCGCGACGCCCCC
CCACCAAGGAGACCTCCGCC

Downstream 100 bases:

>100_bases
GCCGGCCACGCAGCGCATCATCGCGCGAAGCGCGCCAGGCCGTGCTTCGCGTGAAACGATGCTGCAACGCACATCGCCTC
TAGAGGAATCCGCCCACAAA

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: Sialic acid permease [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKISTVTFAISLTLAMRPVGALIFGRLADRFGRRPTLMVN
IALYSLLELASGFAPNLTALFVMRALFGIAMGGEWGVGSALTMETVPPKSRGIVSGLLQAGYPSGYLLASIVFGLFYQYI
GWRGMFMIGVLPALLVLYVRSHVPESPAWKQMEKRPRPSLVATLRHNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLREQH
HFDPHTVSWITIVLNIGAIVGGLAFGSLSEKIGRRRAIFIAALIALPVLPLWAFSSGTVALAAGAFLMQISVQGAWGVIP
VHLNEISPDEIRATFPGFVYQLGNLIASGNAVMQARLASSNGNGNDYSYALALVAGVVAVVIASLILFSRERRGIDMTQS
AARVSSAG

Sequences:

>Translated_408_residues
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKISTVTFAISLTLAMRPVGALIFGRLADRFGRRPTLMVN
IALYSLLELASGFAPNLTALFVMRALFGIAMGGEWGVGSALTMETVPPKSRGIVSGLLQAGYPSGYLLASIVFGLFYQYI
GWRGMFMIGVLPALLVLYVRSHVPESPAWKQMEKRPRPSLVATLRHNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLREQH
HFDPHTVSWITIVLNIGAIVGGLAFGSLSEKIGRRRAIFIAALIALPVLPLWAFSSGTVALAAGAFLMQISVQGAWGVIP
VHLNEISPDEIRATFPGFVYQLGNLIASGNAVMQARLASSNGNGNDYSYALALVAGVVAVVIASLILFSRERRGIDMTQS
AARVSSAG
>Mature_407_residues
SWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKISTVTFAISLTLAMRPVGALIFGRLADRFGRRPTLMVNI
ALYSLLELASGFAPNLTALFVMRALFGIAMGGEWGVGSALTMETVPPKSRGIVSGLLQAGYPSGYLLASIVFGLFYQYIG
WRGMFMIGVLPALLVLYVRSHVPESPAWKQMEKRPRPSLVATLRHNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLREQHH
FDPHTVSWITIVLNIGAIVGGLAFGSLSEKIGRRRAIFIAALIALPVLPLWAFSSGTVALAAGAFLMQISVQGAWGVIPV
HLNEISPDEIRATFPGFVYQLGNLIASGNAVMQARLASSNGNGNDYSYALALVAGVVAVVIASLILFSRERRGIDMTQSA
ARVSSAG

Specific function: May be a sugar-cation symporter involved in sialic acid uptake [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter family. Sialic acid transporter (TC 2.A.1.12.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=351, Percent_Identity=29.0598290598291, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI87082231, Length=400, Percent_Identity=29.5, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788292, Length=449, Percent_Identity=25.3897550111359, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790550, Length=434, Percent_Identity=24.4239631336406, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081723, Length=343, Percent_Identity=29.1545189504373, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786229, Length=384, Percent_Identity=23.1770833333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787880, Length=180, Percent_Identity=26.1111111111111, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788942, Length=436, Percent_Identity=23.6238532110092, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789941, Length=440, Percent_Identity=25.2272727272727, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082159, Length=139, Percent_Identity=33.8129496402878, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17542342, Length=132, Percent_Identity=35.6060606060606, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565976, Length=276, Percent_Identity=24.2753623188406, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=434, Percent_Identity=28.5714285714286, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6320595, Length=166, Percent_Identity=29.5180722891566, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004742 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44419; Mature: 44287

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKISTVTFAISLTLAMRPVG
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ALIFGRLADRFGRRPTLMVNIALYSLLELASGFAPNLTALFVMRALFGIAMGGEWGVGSA
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
LTMETVPPKSRGIVSGLLQAGYPSGYLLASIVFGLFYQYIGWRGMFMIGVLPALLVLYVR
EEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHVPESPAWKQMEKRPRPSLVATLRHNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLREQH
HCCCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
HFDPHTVSWITIVLNIGAIVGGLAFGSLSEKIGRRRAIFIAALIALPVLPLWAFSSGTVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGFVYQLGNLIASGNAVMQARLASS
HHHHHEEEEEEECCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCHHEEEEECCC
NGNGNDYSYALALVAGVVAVVIASLILFSRERRGIDMTQSAARVSSAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFNTKISTVTFAISLTLAMRPVG
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ALIFGRLADRFGRRPTLMVNIALYSLLELASGFAPNLTALFVMRALFGIAMGGEWGVGSA
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
LTMETVPPKSRGIVSGLLQAGYPSGYLLASIVFGLFYQYIGWRGMFMIGVLPALLVLYVR
EEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHVPESPAWKQMEKRPRPSLVATLRHNWKLSIYAVVLMTAFNFFSHGTQDLYPTFLREQH
HCCCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
HFDPHTVSWITIVLNIGAIVGGLAFGSLSEKIGRRRAIFIAALIALPVLPLWAFSSGTVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGFVYQLGNLIASGNAVMQARLASS
HHHHHEEEEEEECCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCHHEEEEECCC
NGNGNDYSYALALVAGVVAVVIASLILFSRERRGIDMTQSAARVSSAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA