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The map label for this gene is hutH [H]

Identifier: 238027406

GI number: 238027406

Start: 1980598

End: 1982208

Strand: Reverse

Name: hutH [H]

Synonym: bglu_1g18020

Alternate gene names: 238027406

Gene position: 1982208-1980598 (Counterclockwise)

Preceding gene: 238027407

Following gene: 238027405

Centisome position: 50.74

GC content: 74.61

Gene sequence:

>1611_bases
ATGGCCATCCTTCGTTCCGAGCGCCCGCTCGACTGGCGCGACATCGCCGCCGTCGCCGCCGGGGCGCCGCTGCACCTTTC
CGACGCGGCGCGTGCGAGCATCGTCGCCGCGCGCGAGCTGGTCGAGCAGATCGTCTCGCGCGCGATCCGCGCCTATGGCA
TGAACACCGGCGTGGGCGCGCTCTGCGACGTGGTGGTGTCGCCCGCCGACCAGCACGATCTCTCGCACCACATCCTGATG
AGCCACGCGGTGGGCGTGGGCGCGCCGCTCGGCCGCGAGGAGACGCGCGCGATCATGGCCGCCGCGATCAACAACTTCGC
GCACGGGCATTCGGGCGTGCGCGTGGAGGTGGTGGAGCGGCTCGCGGTGCTGCTCGAGGCGGACTGCCTGCCCGAGGTGC
CGGCGCTCGGCTCGGTCGGCTACCTGAGCCACATGGCGCATATCGCGCTGGTCTGCGTCGGCGCGGGCCACGTGCGGTGG
CGCGGCGAGCGGCTGACGGGCGCCGACGCGCTGGCCCGGCTCGGGCTCGCGCCGCTCTCGCTCGGCGCCAAGGAGGGCCT
GAGCCTCGTGAACGGCACGCCCTGCGTGACCGGCCTGGCCGCGCTCGCGCTGCAGCGCGCCGGGCGGCTGCTCGACTGGG
CCGACGCCGTGTCGGCGATGAGCTTCGAGAATCTCGGCGGCCAGATGGCCGCCTTCGATGCCGAGGCGCTCGCGTTTCGC
GTCTCGCCGGGGCTCGCCGAGGTGGGGGCGCGCATGCGCGCCGCGCTCGACGGCAGCGGGCTGCTCGCGGCCGCGCTCGG
CCGCCATACGCAGGACCCGCTTAGCATGCGCACCATCCCGCACGTGCACGGCGCCGCGCGCGACGTGCACGCGGCCACCG
CCGAGGTGGTCAACCGCGAACTGGCTTCCACCACCGACAACCCGATCGTGACGGGCACGCCCGACGCGCCGCGCGTGTTT
TCCCAGGCGCACGCGGTGGGCGCCTCGATCGCGCTGGCGATGGACAGCCTGGCGGTGGCCGTGGCGCAGGTCGCGGCGAT
GGCCGAGCGGCGCATCGACCGGCTCGTCAATCCGCTGGTGAGCGGGCTGCCGGCCTTTCTCGCGCAGCCGGGCGGCACGC
GCTCGGGCTTCATGATCGCGCAGTACACGGCGGCCTCGCTGGTCGCCCAGAACCGCCGCGAGGCGGCGCCCGCGAGCCTC
GACGGCGGCGTGACCTCGGGCCTGCAGGAGGACCACCTGTGCCATGCCACGCCGGCCGCGCTGAAGGCGCTGGTGGTGAT
CGAAAATAGCTGCCGGATACTTGGGATAGAATTGCTCGCCGCCGCGCAGGCCTATGATCTGCAGCCGGTCGAGGCGGCGC
GCGCGCCCTACACGGAGGCCCTGCATGCGCGGATTCGCGGCGAGATCGCGACCTACCGCGATGACCGGCCGCTCGCCGAC
GACATCGCGTTCGCGTTCCGGCTGATCGCCGACGGCGCGCCGCCGCCGCTGCCGGACCCCGTGACGGTGCGGCCGGTGGC
GGGCACGCTGGTGTCGGATGCGGCGCCGCCCTCGGCGGGCGGCCCGCTGGCGTCGGCCAACGACGTGCTGCCCGCGGCGA
TCGGCGGCTGA

Upstream 100 bases:

>100_bases
CACGAGGACCGCAATGCCAACTGATTCACCATCCGGACGAAGGTTGCGGATGCAACGGTAGTCCGTCCACCTCATCATCG
TCCGATCCGCAGGTACCGCC

Downstream 100 bases:

>100_bases
CCGGCGGCCTCCTGCGGTCGCGGCCGGCCGATCGCCCCTCACCGACGAAGTCGAGAACAACGATGATCAGGAATCCAGTG
GACGATGCGCAGCAGCCGGC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MAILRSERPLDWRDIAAVAAGAPLHLSDAARASIVAARELVEQIVSRAIRAYGMNTGVGALCDVVVSPADQHDLSHHILM
SHAVGVGAPLGREETRAIMAAAINNFAHGHSGVRVEVVERLAVLLEADCLPEVPALGSVGYLSHMAHIALVCVGAGHVRW
RGERLTGADALARLGLAPLSLGAKEGLSLVNGTPCVTGLAALALQRAGRLLDWADAVSAMSFENLGGQMAAFDAEALAFR
VSPGLAEVGARMRAALDGSGLLAAALGRHTQDPLSMRTIPHVHGAARDVHAATAEVVNRELASTTDNPIVTGTPDAPRVF
SQAHAVGASIALAMDSLAVAVAQVAAMAERRIDRLVNPLVSGLPAFLAQPGGTRSGFMIAQYTAASLVAQNRREAAPASL
DGGVTSGLQEDHLCHATPAALKALVVIENSCRILGIELLAAAQAYDLQPVEAARAPYTEALHARIRGEIATYRDDRPLAD
DIAFAFRLIADGAPPPLPDPVTVRPVAGTLVSDAAPPSAGGPLASANDVLPAAIGG

Sequences:

>Translated_536_residues
MAILRSERPLDWRDIAAVAAGAPLHLSDAARASIVAARELVEQIVSRAIRAYGMNTGVGALCDVVVSPADQHDLSHHILM
SHAVGVGAPLGREETRAIMAAAINNFAHGHSGVRVEVVERLAVLLEADCLPEVPALGSVGYLSHMAHIALVCVGAGHVRW
RGERLTGADALARLGLAPLSLGAKEGLSLVNGTPCVTGLAALALQRAGRLLDWADAVSAMSFENLGGQMAAFDAEALAFR
VSPGLAEVGARMRAALDGSGLLAAALGRHTQDPLSMRTIPHVHGAARDVHAATAEVVNRELASTTDNPIVTGTPDAPRVF
SQAHAVGASIALAMDSLAVAVAQVAAMAERRIDRLVNPLVSGLPAFLAQPGGTRSGFMIAQYTAASLVAQNRREAAPASL
DGGVTSGLQEDHLCHATPAALKALVVIENSCRILGIELLAAAQAYDLQPVEAARAPYTEALHARIRGEIATYRDDRPLAD
DIAFAFRLIADGAPPPLPDPVTVRPVAGTLVSDAAPPSAGGPLASANDVLPAAIGG
>Mature_535_residues
AILRSERPLDWRDIAAVAAGAPLHLSDAARASIVAARELVEQIVSRAIRAYGMNTGVGALCDVVVSPADQHDLSHHILMS
HAVGVGAPLGREETRAIMAAAINNFAHGHSGVRVEVVERLAVLLEADCLPEVPALGSVGYLSHMAHIALVCVGAGHVRWR
GERLTGADALARLGLAPLSLGAKEGLSLVNGTPCVTGLAALALQRAGRLLDWADAVSAMSFENLGGQMAAFDAEALAFRV
SPGLAEVGARMRAALDGSGLLAAALGRHTQDPLSMRTIPHVHGAARDVHAATAEVVNRELASTTDNPIVTGTPDAPRVFS
QAHAVGASIALAMDSLAVAVAQVAAMAERRIDRLVNPLVSGLPAFLAQPGGTRSGFMIAQYTAASLVAQNRREAAPASLD
GGVTSGLQEDHLCHATPAALKALVVIENSCRILGIELLAAAQAYDLQPVEAARAPYTEALHARIRGEIATYRDDRPLADD
IAFAFRLIADGAPPPLPDPVTVRPVAGTLVSDAAPPSAGGPLASANDVLPAAIGG

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=480, Percent_Identity=36.875, Blast_Score=271, Evalue=9e-73,
Organism=Caenorhabditis elegans, GI17567831, Length=478, Percent_Identity=35.7740585774059, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 55200; Mature: 55069

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILRSERPLDWRDIAAVAAGAPLHLSDAARASIVAARELVEQIVSRAIRAYGMNTGVGA
CCCCCCCCCCCHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LCDVVVSPADQHDLSHHILMSHAVGVGAPLGREETRAIMAAAINNFAHGHSGVRVEVVER
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LAVLLEADCLPEVPALGSVGYLSHMAHIALVCVGAGHVRWRGERLTGADALARLGLAPLS
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHCCCHHC
LGAKEGLSLVNGTPCVTGLAALALQRAGRLLDWADAVSAMSFENLGGQMAAFDAEALAFR
CCHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECHHHEEEE
VSPGLAEVGARMRAALDGSGLLAAALGRHTQDPLSMRTIPHVHGAARDVHAATAEVVNRE
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHCCCCCHHCCHHHHHHHHHHHHHHH
LASTTDNPIVTGTPDAPRVFSQAHAVGASIALAMDSLAVAVAQVAAMAERRIDRLVNPLV
HHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLPAFLAQPGGTRSGFMIAQYTAASLVAQNRREAAPASLDGGVTSGLQEDHLCHATPAA
HCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCHHH
LKALVVIENSCRILGIELLAAAQAYDLQPVEAARAPYTEALHARIRGEIATYRDDRPLAD
HHEEEEEECCCCEEHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCHHCCCCCCCCHH
DIAFAFRLIADGAPPPLPDPVTVRPVAGTLVSDAAPPSAGGPLASANDVLPAAIGG
HHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AILRSERPLDWRDIAAVAAGAPLHLSDAARASIVAARELVEQIVSRAIRAYGMNTGVGA
CCCCCCCCCCHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LCDVVVSPADQHDLSHHILMSHAVGVGAPLGREETRAIMAAAINNFAHGHSGVRVEVVER
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LAVLLEADCLPEVPALGSVGYLSHMAHIALVCVGAGHVRWRGERLTGADALARLGLAPLS
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHCCCHHC
LGAKEGLSLVNGTPCVTGLAALALQRAGRLLDWADAVSAMSFENLGGQMAAFDAEALAFR
CCHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECHHHEEEE
VSPGLAEVGARMRAALDGSGLLAAALGRHTQDPLSMRTIPHVHGAARDVHAATAEVVNRE
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHCCCCCHHCCHHHHHHHHHHHHHHH
LASTTDNPIVTGTPDAPRVFSQAHAVGASIALAMDSLAVAVAQVAAMAERRIDRLVNPLV
HHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLPAFLAQPGGTRSGFMIAQYTAASLVAQNRREAAPASLDGGVTSGLQEDHLCHATPAA
HCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCHHH
LKALVVIENSCRILGIELLAAAQAYDLQPVEAARAPYTEALHARIRGEIATYRDDRPLAD
HHEEEEEECCCCEEHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCHHCCCCCCCCHH
DIAFAFRLIADGAPPPLPDPVTVRPVAGTLVSDAAPPSAGGPLASANDVLPAAIGG
HHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA